MG1655
W3110
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Gene Report : ileS
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
J Biol Chem. 1985;260(9):5610-5.
Identification of prolipoprotein signal peptidase and genomic organization of the lsp gene in Escherichia coli.
Tokunaga M, Loranger JM, Chang SY, Regue M, Chang S, Wu HC. ( 2580835 )
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  ileS
Related strains
     Strains Search Search strains by gene name:  ileS   Search strains by all related name:  ileS b0026 ECK0027 ilvS JW0024

General information  (Go to Linear View:)
 Gene Name ileS  
 Alternative name b0026,ECK0027,ilvS,JW0024  
 Location, Length 22,391 - 25,207 (  +  ) ;   0.48 min ; 2817 (bp) ,   938 (aa) Go to Linear View
 Product isoleucyl-tRNA synthetase  
 Note ECK0027:JW0024:b0026  
 Function  
 PID 85674290  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) SYI_ECOLI ( P00956 ; P78038; Q59429 )
    -  Protein name RecName: Full=Isoleucyl-tRNA synthetase; EC=6.1.1.5; AltName: Full=Isoleucine--tRNA ligase; Short=IleRS;  
    -  Synonyms  
    -  Gene name Name=ileS; Synonyms=ilvS; OrderedLocusNames=b0026, JW0024;  

 Linear View
View Location
   10.0  –  35.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Isoleucyl-tRNA synthetase; AltName: Full=Isoleucine--tRNA ligase; Short=IleRS  
         PSI-BLAST RecName: Full=Isoleucyl-tRNA synthetase; AltName: Full=Isoleucine--tRNA ligase; Short=IleRS
    nr
         BLAST isoleucyl-tRNA synthetase [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc ileS 

Sequences
Amino acid
FASTA format
0001 MSDYKSTLNL PETGFPMRGD LAKREPGMLA RWTDDDLYGI IRAAKKGKKT FILHDGPPYA NGSIHIGHSV 
0071 NKILKDIIVK SKGLSGYDSP YVPGWDCHGL PIELKVEQEY GKPGEKFTAA EFRAKCREYA ATQVDGQRKD 
0141 FIRLGVLGDW SHPYLTMDFK TEANIIRALG KIIGNGHLHK GAKPVHWCVD CRSALAEAEV EYYDKTSPSI 
0211 DVAFQAVDQD ALKAKFAVSN VNGPISLVIW TTTPWTLPAN RAISIAPDFD YALVQIDGQA VILAKDLVES 
0281 VMQRIGVTDY TILGTVKGAE LELLRFTHPF MGFDVPAILG DHVTLDAGTG AVHTAPGHGP DDYVIGQKYG 
0351 LETANPVGPD GTYLPGTYPT LDGVNVFKAN DIVVALLQEK GALLHVEKMQ HSYPCCWRHK TPIIFRATPQ 
0421 WFVSMDQKGL RAQSLKEIKG VQWIPDWGQA RIESMVANRP DWCISRQRTW GVPMSLFVHK DTEELHPRTL 
0491 ELMEEVAKRV EVDGIQAWWD LDAKEILGDE ADQYVKVPDT LDVWFDSGST HSSVVDVRPE FAGHAADMYL 
0561 EGSDQHRGWF MSSLMISTAM KGKAPYRQVL THGFTVDGQG RKMSKSIGNT VSPQDVMNKL GADILRLWVA 
0631 STDYTGEMAV SDEILKRAAD SYRRIRNTAR FLLANLNGFD PAKDMVKPEE MVVLDRWAVG CAKAAQEDIL 
0701 KAYEAYDFHE VVQRLMRFCS VEMGSFYLDI IKDRQYTAKA DSVARRSCQT ALYHIAEALV RWMAPILSFT 
0771 ADEVWGYLPG EREKYVFTGE WYEGLFGLAD SEAMNDAFWD ELLKVRGEVN KVIEQARADK KVGGSLEAAV 
0841 TLYAEPELSA KLTALGDELR FVLLTSGATV ADYNDAPADA QQSEVLKGLK VALSKAEGEK CPRCWHYTQD 
0911 VGKVAEHAEI CGRCVSNVAG DGEKRKFA

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GATTGCGCGT GATGAATTAA CCGCCCGCGA 
-070 ATTTTTTGGG CTAACAAAAC CGGCTTAAGC CTGTTATGTA ATCAAACCGA AATACGGAAC CGAGAATCTG 
0001 atgagtgact ataaatcaac cctgaatttg ccggaaacag ggttcccgat gcgtggcgat ctcgccaagc 
0071 gcgaacccgg aatgctggcg cgttggactg atgatgatct gtacggcatc atccgtgcgg ctaaaaaagg 
0141 caaaaaaacc ttcattctgc atgatggccc tccttatgcg aatggcagca ttcatattgg tcactcggtt 
0211 aacaagattc tgaaagacat tatcgtgaag tccaaagggc tttccggtta tgactcgccg tatgtgcctg 
0281 gctgggactg ccacggtctg ccgatcgagc tgaaagtcga gcaagaatac ggtaagccgg gtgagaaatt 
0351 caccgccgcc gagttccgcg ccaagtgccg cgaatacgcg gcgacccagg ttgacggtca acgcaaagac 
0421 tttatccgtc tgggcgtgct gggcgactgg tcgcacccgt acctgaccat ggacttcaaa actgaagcca 
0491 acatcatccg cgcgctgggc aaaatcatcg gcaacggtca cctgcacaaa ggcgcgaagc cagttcactg 
0561 gtgcgttgac tgccgttctg cgctggcgga agcggaagtt gagtattacg acaaaacttc tccgtccatc 
0631 gacgttgctt tccaggcagt cgatcaggat gcactgaaag caaaatttgc cgtaagcaac gttaacggcc 
0701 caatctcgct ggtaatctgg accaccacgc cgtggactct gcctgccaac cgcgcaatct ctattgcacc 
0771 agatttcgac tatgcgctgg tgcagatcga cggtcaggcc gtgattctgg cgaaagatct ggttgaaagc 
0841 gtaatgcagc gtatcggcgt gaccgattac accattctcg gcacggtaaa aggtgcggag cttgagctgc 
0911 tgcgctttac ccatccgttt atgggcttcg acgttccggc aatcctcggc gatcacgtta ccctggatgc 
0981 cggtaccggt gccgttcaca ccgcgcctgg ccacggcccg gacgactatg tgatcggtca gaaatacggc 
1051 ctggaaaccg ctaacccggt tggcccggac ggcacttatc tgccgggcac ttatccgacg ctggatggcg 
1121 tgaacgtctt caaagcgaac gacatcgtcg ttgcgctgct gcaggaaaaa ggcgcgctgc tgcacgttga 
1191 gaaaatgcag cacagctatc cgtgctgctg gcgtcacaaa acgccgatca tcttccgcgc gacgccgcag 
1261 tggttcgtca gcatggatca gaaaggtctg cgtgcgcagt cactgaaaga gatcaaaggc gtgcagtgga 
1331 tcccggactg gggccaggcg cgtatcgagt cgatggttgc taaccgtcct gactggtgta tctcccgtca 
1401 gcgcacctgg ggtgtaccga tgtcactgtt cgtgcacaaa gacacggaag agctgcatcc gcgtaccctt 
1471 gaactgatgg aagaagtggc aaaacgcgtt gaagtcgatg gcatccaggc gtggtgggat ctcgatgcga 
1541 aagagatcct cggcgacgaa gctgatcagt acgtgaaagt gccggacaca ttggatgtat ggtttgactc 
1611 cggatctacc cactcttctg ttgttgacgt gcgtccggaa tttgccggtc acgcagcgga catgtatctg 
1681 gaaggttctg accaacaccg cggctggttc atgtcttccc taatgatctc caccgcgatg aagggtaaag 
1751 cgccgtatcg tcaggtactg acccacggct ttaccgtgga tggtcagggc cgcaagatgt ctaaatccat 
1821 cggcaatacc gtttcgccgc aggatgtgat gaacaaactg ggcgcggata ttctgcgtct gtgggtggca 
1891 tcaaccgact acaccggtga aatggccgtt tctgacgaga tcctgaaacg tgctgccgat agctatcgtc 
1961 gtatccgtaa caccgcgcgc ttcctgctgg caaacctgaa cggttttgat ccagcaaaag atatggtgaa 
2031 accggaagag atggtggtac tggatcgctg ggccgtaggt tgtgcgaaag cggcacagga agacatcctc 
2101 aaggcgtacg aagcatacga tttccacgaa gtggtacagc gtctgatgcg cttctgctcc gttgagatgg 
2171 gttccttcta cctcgacatc atcaaagacc gtcagtacac cgccaaagcg gacagtgtgg cgcgtcgtag 
2241 ctgccagact gcgctatatc acatcgcaga agcgctggtg cgctggatgg caccaatcct ctccttcacc 
2311 gctgatgaag tgtggggcta cctgccgggc gaacgtgaaa aatacgtctt caccggtgag tggtacgaag 
2381 gcctgtttgg cctggcagac agtgaagcga tgaacgatgc gttctgggac gagctgttga aagtgcgtgg 
2451 cgaagtgaac aaagtcattg agcaagcgcg tgccgacaag aaagtgggtg gctcgctgga agcggcagta 
2521 accttgtatg cagaaccgga actgtcggcg aaactgaccg cgctgggcga tgaattacga tttgtcctgt 
2591 tgacctccgg cgctaccgtt gcagactata acgacgcacc tgctgatgct cagcagagcg aagtactcaa 
2661 agggctgaaa gtcgcgttga gtaaagccga aggtgagaag tgcccacgct gctggcacta cacccaggat 
2731 gtcggcaagg tggcggaaca cgcagaaatc tgcggccgct gtgtcagcaa cgtcgccggt gacggtgaaa 
2801 aacgtaagtt tgcctgaTGA GTCAATCGAT CTGTTCAACA GGGCTACGCT GGCTGTGGCT GGTGGTAGTC 
2871 GTGCTGATTA TCGATCTGGG CAGCAAATAC CTGATCCTCC AGAACTT