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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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J Bacteriol. 2000;182(6):1754-6.
AcrD of Escherichia coli is an aminoglycoside efflux pump.
Rosenberg EY, Ma D, Nikaido H.
(
10692383
)
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Related gene (MG1655 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
acrD
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Related strains
|
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Strains Search
|
Search strains by gene name:
acrD
Search strains by all related name:
acrD b2470 ECK2465 JW2454 yffA
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General information (Go to Linear View: )
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Gene Name
|
acrD
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Alternative name
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b2470,ECK2465,JW2454,yffA
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Location, Length
|
2,586,251 - 2,589,364
(
+
)
;
55.66
min
;
3114
(bp) ,
1037
(aa)
|
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Product
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aminoglycoside/multidrug efflux system
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Note
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ECK2465:JW2454:b2470
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Function
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PID
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1799893
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SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
ACRD_ECOLI
(
P24177
;
P76971; P77178; Q46715
)
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- Protein name
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RecName: Full=Probable aminoglycoside efflux pump; AltName: Full=Acriflavine resistance protein D;
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- Synonyms
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- Gene name
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Name=acrD; Synonyms=yffA; OrderedLocusNames=b2470, JW2454;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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PDB
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PSI-BLAST
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SWISS-PROT
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BLAST
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PSI-BLAST
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nr
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BLAST
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aminoglycoside/multidrug efflux system [Escherichia coli str. K-12 substr. MG1655]
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Pfam 27.0
(database updated :
2013-03
)
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Pfam
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| Sequences |
Amino acid
FASTA format
|
0001 MANFFIDRPI FAWVLAILLC LTGTLAIFSL PVEQYPDLAP PNVRVTANYP GASAQTLENT VTQVIEQNMT
0071 GLDNLMYMSS QSSGTGQASV TLSFKAGTDP DEAVQQVQNQ LQSAMRKLPQ AVQNQGVTVR KTGDTNILTI
0141 AFVSTDGSMD KQDIADYVAS NIQDPLSRVN GVGDIDAYGS QYSMRIWLDP AKLNSFQMTA KDVTDAIESQ
0211 NAQIAVGQLG GTPSVDKQAL NATINAQSLL QTPEQFRDIT LRVNQDGSEV RLGDVATVEM GAEKYDYLSR
0281 FNGKPASGLG VKLASGANEM ATAELVLNRL DELAQYFPHG LEYKVAYETT SFVKASIEDV VKTLLEAIAL
0351 VFLVMYLFLQ NFRATLIPTI AVPVVLMGTF SVLYAFGYSV NTLTMFAMVL AIGLLVDDAI VVVENVERIM
0421 SEEGLTPREA TRKSMGQIQG ALVGIAMVLS AVFVPMAFFG GTTGAIYRQF SITIVAAMVL SVLVAMILTP
0491 ALCATLLKPL KKGEHHGQKG FFAWFNQMFN RNAERYEKGV AKILHRSLRW IVIYVLLLGG MVFLFLRLPT
0561 SFLPLEDRGM FTTSVQLPSG STQQQTLKVV EQIEKYYFTH EKDNIMSVFA TVGSGPGGNG QNVARMFIRL
0631 KDWSERDSKT GTSFAIIERA TKAFNQIKEA RVIASSPPAI SGLGSSAGFD MELQDHAGAG HDALMAARNQ
0701 LLALAAENPE LTRVRHNGLD DSPQLQIDID QRKAQALGVA IDDINDTLQT AWGSSYVNDF MDRGRVKKVY
0771 VQAAAPYRML PDDINLWYVR NKDGGMVPFS AFATSRWETG SPRLERYNGY SAVEIVGEAA PGVSTGTAMD
0841 IMESLVKQLP NGFGLEWTAM SYQERLSGAQ APALYAISLL VVFLCLAALY ESWSVPFSVM LVVPLGVIGA
0911 LLATWMRGLE NDVYFQVGLL TVIGLSAKNA ILIVEFANEM NQKGHDLFEA TLHACRQRLR PILMTSLAFI
0981 FGVLPMATST GAGSGGQHAV GTGVMGGMIS ATILAIYFVP LFFVLVRRRF PLKPRPE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CATTAACTCC TTTTTTTCTC CACGATTGGC
-070 TCGTACCTTG CCGCTACAGT GAAGCAAGTC AAGCCTACAA CGATACGCAG AAACACGAGG TCCTCTTTTA
0001 atggcgaatt tctttattga tcgccccatt tttgcctggg tgctggcaat cctgttgtgt ctgacaggta
0071 ccctggcgat tttttcattg cccgttgaac aataccccga tctcgcgcca ccgaatgtgc gagtgaccgc
0141 taactatccc ggcgcatcgg cccagacgct ggaaaacacc gtgacccagg ttatcgagca aaatatgacc
0211 ggcctcgata atctcatgta tatgtcatct cagagcagtg gcaccggtca ggcatctgtc actttaagtt
0281 ttaaagcagg caccgatccg gacgaagccg tgcagcaagt acaaaaccag ctgcaatcag ccatgcgaaa
0351 gttaccgcag gcggtgcaaa atcagggcgt gacggtgcgt aaaaccggcg ataccaacat tctgaccatt
0421 gccttcgtct ctaccgatgg ttcgatggat aaacaggata ttgctgatta tgttgccagt aatattcagg
0491 acccgttaag ccgcgtgaat ggcgtcgggg atatcgatgc ctatggttcg caatattcca tgcgtatctg
0561 gctggacccg gcgaaactca acagtttcca gatgacggct aaagatgtca ctgatgccat tgagtcacag
0631 aacgcgcaga ttgcggttgg gcaacttggt ggtacacctt ccgtcgataa gcaggcgctc aacgccacca
0701 ttaacgccca gtcactgctg caaacaccag aacagttccg cgatatcacc ttgcgggtca atcaggacgg
0771 ctcagaggta aggctgggcg atgtcgccac cgtcgaaatg ggggcggaga aatacgatta tcttagccgc
0841 ttcaatggta agccagcctc cgggctgggg gtaaaactgg cctccggcgc taacgaaatg gcgacagcgg
0911 agctggtgct caatcgtctc gacgagctgg cgcagtattt cccgcatgga ctggaataca aggtggcgta
0981 tgaaaccacc tcgtttgtta aagcctccat tgaagacgtg gtgaaaacgc tgctggaagc tatcgctctg
1051 gttttcctcg ttatgtatct gttcctgcaa aacttccgcg ccacgctgat acccactatc gccgtgccgg
1121 tggtgttgat gggaaccttc tccgtacttt acgccttcgg ttacagcgtc aacaccttaa ccatgttcgc
1191 gatggtgctg gcgatcggtc tgctggtgga tgacgccatc gtggtggtgg aaaacgtcga acgtattatg
1261 agtgaggaag gactcactcc tcgcgaagcc acacgtaaat cgatggggca gatccagggg gcactggtcg
1331 ggattgcgat ggttctttcg gcggtatttg taccaatggc cttcttcggc ggcaccaccg gtgccatcta
1401 tcgccagttc tctattacca ttgttgcggc gatggtgctg tcagtactgg tagcgatgat cctcactccg
1471 gctctgtgtg ccacactact taagccactg aaaaaaggtg agcatcatgg gcaaaaaggc ttttttgcct
1541 ggtttaacca gatgtttaac cgcaacgccg aacgctacga aaaaggggtg gcgaaaattc tccaccgtag
1611 cctgcgctgg attgtgattt atgtcctgct gcttggcggc atggtgttcc tgttcctgcg tttgccgacg
1681 tcgttcttac cgctggaaga ccgtggcatg tttactacct cggtacagtt gcccagcggt tcaacgcaac
1751 aacagaccct gaaagtcgtt gagcaaatcg agaaatacta cttcacccat gaaaaagaca acatcatgtc
1821 ggtgtttgcc accgttggtt ctggccctgg gggtaacggg caaaacgtgg cgcgaatgtt tatccgcctg
1891 aaagactgga gcgaacgcga cagtaagacc ggcacctcgt ttgccattat cgagcgtgca acgaaggcgt
1961 ttaaccaaat taaagaagct cgcgttatcg ccagcagccc gccagcaatt agcggtcttg gtagttctgc
2031 aggttttgat atggagttgc aggaccacgc tggagcgggt cacgatgcgc tgatggcagc acgtaatcag
2101 ttgctggcgc tggcggcgga aaacccggag ctaacccgtg tgcgccataa cggcctcgac gacagtccgc
2171 agttgcagat tgatatcgac cagcgtaaag ctcaggcgct gggcgttgct atcgacgata ttaacgacac
2241 actgcaaacc gcctggggtt cgagctatgt gaatgacttt atggatcgcg gtcgcgtgaa gaaagtctat
2311 gtgcaggcag ctgcgccgta tcgcatgctg ccagatgaca tcaatctctg gtatgtccga aataaagatg
2381 gcggcatggt gcccttctct gctttcgcga cctcacgctg ggaaacaggc tcgccgcgtc tggaacgcta
2451 taacggttat tctgcggttg agattgttgg ggaagccgca ccgggggtca gtaccggtac ggcgatggat
2521 attatggaat cgttagtgaa gcagctgcca aacggctttg gtctggagtg gacggcgatg tcgtatcagg
2591 agcggctttc cggcgcgcag gctccggcgc tgtacgccat ttccttgctg gtggtattcc tgtgtctggc
2661 tgcgttgtat gaaagctggt cggtgccgtt ctcggtaatg ctggtcgtgc cgctgggggt aatcggcgcg
2731 ctgctggcaa cctggatgcg cgggctggaa aacgacgttt acttccaggt gggcctgtta acggtcattg
2801 gtttatcggc gaaaaacgcc atcctgatcg tcgagtttgc taacgagatg aaccaaaaag gccacgacct
2871 gtttgaagcg acgctccacg cctgccgtca gcgtttacgc ccgattctga tgacctcgct ggcatttatc
2941 ttcggcgtat tgccaatggc aaccagcacg ggtgccggtt ccggtggtca gcatgcggtg ggtactggcg
3011 taatgggcgg gatgatttcg gccactattc tggctattta cttcgtgccg ctgttctttg tgctggtgcg
3081 ccgccgcttc ccgctgaagc cgcgcccgga ataaGCAATA AAAAAGGCGA CATGCCAATG TGTCGCCTTT
3151 TTCAACTTTC CGATTAAGAA CCTGCTCAGC GGGTTCTTGC TGTTTGTACT TTGTCTCAGG AATT
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