MG1655
W3110
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Gene Report : lpxA
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  lpxA
Related strains
     Strains Search Search strains by gene name:  lpxA   Search strains by all related name:  lpxA b0181 ECK0180 JW0176

General information  (Go to Linear View:)
 Gene Name lpxA  
 Alternative name b0181,ECK0180,JW0176  
 Location, Length 202,560 - 203,348 (  +  ) ;   4.36 min ; 789 (bp) ,   262 (aa) Go to Linear View
 Product UDP-N-acetylglucosamine acetyltransferase  
 Note ECK0180:JW0176:b0181  
 Function  
 PID 85674370  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) LPXA_ECOLI ( P0A722 ; P10440; P78243 )
    -  Protein name RecName: Full=Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Short=UDP-N-acetylglucosamine acyltransferase; EC=2.3.1.129;  
    -  Synonyms  
    -  Gene name Name=lpxA; OrderedLocusNames=b0181, JW0176;  

 Linear View
View Location
   190.0  –  215.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Short=UDP-N-acetylglucosamine acyltransferase  
         PSI-BLAST RecName: Full=Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Short=UDP-N-acetylglucosamine acyltransferase
    nr
         BLAST UDP-N-acetylglucosamine acetyltransferase [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc lpxA 

MMBR References
J Bacteriol. 1987;169(12):5727-34.
Nucleotide sequence of the Escherichia coli gene for lipid A disaccharide synthase.
Crowell DN, Reznikoff WS, Raetz CRH. ( 2824445 )

Sequences
Amino acid
FASTA format
0001 MIDKSAFVHP TAIVEEGASI GANAHIGPFC IVGPHVEIGE GTVLKSHVVV NGHTKIGRDN EIYQFASIGE 
0071 VNQDLKYAGE PTRVEIGDRN RIRESVTIHR GTVQGGGLTK VGSDNLLMIN AHIAHDCTVG NRCILANNAT 
0141 LAGHVSVDDF AIIGGMTAVH QFCIIGAHVM VGGCSGVAQD VPPYVIAQGN HATPFGVNIE GLKRRGFSRE 
0211 AITAIRNAYK LIYRSGKTLD EVKPEIAELA ETYPEVKAFT DFFARSTRGL IR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GCGCCGCGGC CTGACCCGTT TTAAAGGGGT 
-070 TGCTCTGGTC GATGGTAAAG TAGTTTGCGA AGCAACGATG ATGTGTGCTC GTAGCCGGGA GGCCTGATAC 
0001 gtgattgata aatccgcctt tgtgcatcca accgccattg tggaagaggg cgcgtcaatt ggcgcgaacg 
0071 cacacattgg tcctttttgt atcgttggac cccatgtcga aattggtgag ggtaccgtac tgaaatctca 
0141 cgttgtcgtg aatggtcata ctaaaattgg ccgcgataat gagatttatc agttcgcctc catcggcgaa 
0211 gttaaccagg atctgaaata tgctggcgaa ccgacccgtg tggaaatcgg cgatcgtaac cgcattcgcg 
0281 aaagcgtcac cattcatcgt ggcacagtcc agggcggtgg attgacgaag gtgggcagcg acaacttact 
0351 gatgatcaac gcgcacattg cgcacgattg tacggtaggt aaccgctgta ttctcgccaa caacgcaacg 
0421 ctggcgggtc acgtatcggt tgacgacttc gcgatcatcg gcggcatgac cgcagtccat cagttctgca 
0491 tcattggtgc gcacgtgatg gttggcggct gctccggtgt ggcgcaggac gtccctcctt atgtcattgc 
0561 gcagggtaac cacgcaacgc cgttcggtgt caatatcgaa gggctgaagc gccgcggatt cagccgtgag 
0631 gcgattaccg ctatccgcaa tgcgtataag ctgatttatc gtagcggtaa aacgctcgat gaagtgaaac 
0701 cggaaattgc tgaactggcg gaaacatatc cggaagtgaa agcctttacc gatttctttg cacgctcaac 
0771 gcgcggtctg attcgttaaT GACTGAACAG CGTCCATTAA CGATTGCCCT GGTCGCCGGA GAAACCTCCG 
0841 GCGATATCCT GGGGGCCGGT TTAATCCGCG CTCTGAAAGA ACATGTGCC