MG1655
W3110
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Gene Report : lpxD
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  lpxD
Related strains
     Strains Search Search strains by gene name:  lpxD   Search strains by all related name:  lpxD b0179 ECK0178 firA JW0174 omsA ssc

General information  (Go to Linear View:)
 Gene Name lpxD  
 Alternative name b0179,ECK0178,firA,JW0174,omsA,ssc  
 Location, Length 200,971 - 201,996 (  +  ) ;   4.33 min ; 1026 (bp) ,   341 (aa) Go to Linear View
 Product UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase  
 Note ECK0178:JW0174:b0179  
 Function  
 PID 4902920  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) LPXD_ECOLI ( P21645 )
    -  Protein name RecName: Full=UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; EC=2.3.1.-; AltName: Full=Protein firA; AltName: Full=Rifampicin resistance protein;  
    -  Synonyms  
    -  Gene name Name=lpxD; Synonyms=firA, omsA; OrderedLocusNames=b0179, JW0174;  

 Linear View
View Location
   190.0  –  215.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; AltName: Full=Protein firA; AltName: Full=Rifampicin resistance protein  
         PSI-BLAST RecName: Full=UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; AltName: Full=Protein firA; AltName: Full=Rifampicin resistance protein
    nr
         BLAST UDP-3-O-  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc lpxD 

MMBR References
J Bacteriol. 1988;170(3):1268-74.
First committed step of lipid A biosynthesis in Escherichia coli: sequence of the lpxA gene.
Coleman J, Raetz CRH. ( 3277952 )

Sequences
Amino acid
FASTA format
0001 MPSIRLADLA QQLDAELHGD GDIVITGVAS MQSAQTGHIT FMVNPKYREH LGLCQASAVV MTQDDLPFAK 
0071 SAALVVKNPY LTYARMAQIL DTTPQPAQNI APSAVIDATA KLGNNVSIGA NAVIESGVEL GDNVIIGAGC 
0141 FVGKNSKIGA GSRLWANVTI YHEIQIGQNC LIQSGTVVGA DGFGYANDRG NWVKIPQIGR VIIGDRVEIG 
0211 ACTTIDRGAL DDTIIGNGVI IDNQCQIAHN VVIGDNTAVA GGVIMAGSLK IGRYCMIGGA SVINGHMEIC 
0281 DKVTVTGMGM VMRPITEPGV YSSGIPLQPN KVWRKTAALV MNIDDMSKRL KSLERKVNQQ D

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             CCAGGATATC GATCTGGTTG TTGATGCAAA 
-070 CGCCGTTGCT TACAACAGCA GCGATGTAAA AGACATCACT GCCGACGTAC TGAAACAGGT TAAATAAGTA 
0001 atgccttcaa ttcgactggc tgatttagcg cagcagttgg atgcagaact acacggtgat ggcgatatcg 
0071 tcatcaccgg cgttgcgtcc atgcaatctg cacaaacagg tcacattacg ttcatggtta acccaaaata 
0141 ccgtgagcat ttaggcttgt gccaggcgtc cgcggttgtc atgacccagg acgatcttcc tttcgcgaaa 
0211 agtgccgcac tggtagtgaa gaatccctac ctgacttacg cgcgcatggc gcaaatttta gataccacgc 
0281 cgcagcccgc gcagaacatt gcacccagtg cggtgatcga cgcgacggcg aagctgggta acaacgtatc 
0351 gattggcgct aacgcggtga ttgagtccgg cgttgaactg ggcgataacg tgattatcgg tgccggttgc 
0421 ttcgtaggta aaaacagcaa aatcggtgca ggttcgcgtc tctgggcgaa cgtaaccatt taccatgaga 
0491 tccagatcgg tcagaattgc ctgatccagt ccggaacagt ggtaggcgca gacggctttg gttatgccaa 
0561 cgatcgtggt aactgggtga agatcccaca gattggtcgc gtaattattg gcgatcgcgt ggagatcggt 
0631 gcctgcacaa ccatcgatcg cggcgcgctg gatgacacta ttattggcaa tggcgtgatc attgataacc 
0701 agtgccagat tgcacataac gtcgtgattg gcgacaatac ggcggttgcc ggtggcgtca ttatggcggg 
0771 cagcctgaaa attggtcgtt actgcatgat cggcggagcc agcgtaatca acgggcatat ggaaatatgc 
0841 gacaaagtga cggttacggg catgggtatg gtgatgcgtc ccatcactga accaggcgtc tattcctcag 
0911 gcattccgct gcaacccaac aaagtctggc gcaaaaccgc tgcactggtg atgaacattg atgacatgag 
0981 caagcgtctg aaatcgcttg agcgcaaggt taatcaacaa gactaaCGTT CCATCTTTTG TTCGCCAAAC 
1051 TTTACGGCCT GTCTCATTCT TACGATTGCG GCAGGCCGTG TTATTATTGT CGTTTCTTAT ATTTTGACAG 
1121 GAAGAG