MG1655
W3110
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Gene Report : cdsA
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
J Bacteriol. 1999;181(9):2733-8.
The Escherichia coli homologue of yeast RER2, a key enzyme of dolichol synthesis, is essential for carrier lipid formation in bacterial cell wall synthesis.
Kato J, Fujisaki S, Nakajima K, Nishimura Y, Sato M, Nakano A. ( 10217761 )
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  cdsA
Related strains
     Strains Search Search strains by gene name:  cdsA   Search strains by all related name:  cdsA b0175 ECK0174 JW5810

General information  (Go to Linear View:)
 Gene Name cdsA  
 Alternative name b0175,ECK0174,JW5810  
 Location, Length 195,677 - 196,534 (  +  ) ;   4.21 min ; 858 (bp) ,   285 (aa) Go to Linear View
 Product CDP-diglyceride synthase  
 Note ECK0174:JW5810:b0175  
 Function  
 PID 85674368  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) CDSA_ECOLI ( P0ABG1 ; P06466 )
    -  Protein name RecName: Full=Phosphatidate cytidylyltransferase; EC=2.7.7.41; AltName: Full=CDP-diglyceride pyrophosphorylase; AltName: Full=CDP-diglyceride synthetase; AltName: Full=CDP-diacylglycerol synthase; Short=CDS; AltName: Full=CTP:phosphatidate cytidylyltransferase; AltName: Full=CDP-DG synthetase; AltName: Full=CDP-DAG synthase;  
    -  Synonyms  
    -  Gene name Name=cdsA; Synonyms=cds; OrderedLocusNames=b0175, JW5810;  

 Linear View
View Location
   185.0  –  210.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
        BLAST  
        PSI-BLAST
    nr
         BLAST CDP-diglyceride synthase [Escherichia coli str. K-12 substr. W3110]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc cdsA 

Sequences
Amino acid
FASTA format
0001 MLKYRLISAF VLIPVVIAAL FLLPPVGFAI VTLVVCMLAA WEWGQLSGFT TRSQRVWLAV LCGLLLALML 
0071 FLLPEYHRNI HQPLVEISLW ASLGWWIVAL LLVLFYPGSA AIWRNSKTLR LIFGVLTIVP FFWGMLALRA 
0141 WHYDENHYSG AIWLLYVMIL VWGADSGAYM FGKLFGKHKL APKVSPGKTW QGFIGGLATA AVISWGYGMW 
0211 ANLDVAPVTL LICSIVAALA SVLGDLTESM FKREAGIKDS GHLIPGHGGI LDRIDSLTAA VPVFACLLLL 
0281 VFRTL

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TGAACAAGAC TTTGAAGGGG CGTTAAATGC 
-070 CTTTGCTAAT CGAGAGCGTC GTTTCGGCGG CACCGAGCCC GGTGATGAAA CAGCCTGATG GGGGTCGCTT 
0001 ttgctgaagt atcgcctgat atctgctttt gtgttaatac ccgtcgtcat cgcggcgttg tttctgttgc 
0071 cgccggtggg gttcgccatt gtaacgctgg tggtctgcat gctggcagcg tgggaatggg gacagcttag 
0141 cggttttacc actcgttcgc agcgagtatg gttggcggtg ttatgcgggt tattgttggc gctgatgctt 
0211 tttctgttgc cggaatatca ccgaaatatt catcaaccgc tggttgaaat ctcactttgg gcttcgctgg 
0281 gttggtggat tgtcgcgcta ttgctggtgc tgttttaccc aggttccgca gcaatctggc gtaactctaa 
0351 aacattgcgc cttatttttg gcgtgctaac cattgttccc ttcttctggg gcatgctggc gttacgggcc 
0421 tggcactatg acgagaatca ttacagtggc gcaatatggc tgctctatgt catgatcctg gtatggggcg 
0491 ctgactccgg cgcatatatg tttggcaaat tgtttggtaa acataagctg gcaccgaagg tttctccggg 
0561 taaaacctgg caaggcttta tcggtggact cgctactgca gcggtaatct catggggtta tggcatgtgg 
0631 gcgaatctcg acgtcgctcc cgtcacctta ctcatttgct ctattgtcgc agcgttagcc tcagtgctcg 
0701 gcgatctgac cgagagtatg tttaagcgtg aagcaggaat taaggacagc ggtcatttaa ttccaggaca 
0771 cggtggtatt ttagatcgta ttgatagcct gacggctgcg gtaccggtct ttgcttgctt gttgttactg 
0841 gtattcagga cgctttaaCG GAAGGTAATA TGCTGAGTTT TCTCTGGGAT TTGGCTTCGT TCATCGTTGC 
0911 ACTGGGTGTA CTTATCACCG TGCATGAATT TGGTCATTTC TGGGTTGC