MG1655
W3110
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Gene Report : pyrH
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  pyrH
Related strains
     Strains Search Search strains by gene name:  pyrH   Search strains by all related name:  pyrH b0171 ECK0170 JW0166 smbA umk

General information  (Go to Linear View:)
 Gene Name pyrH  
 Alternative name b0171,ECK0170,JW0166,smbA,umk  
 Location, Length 191,855 - 192,580 (  +  ) ;   4.13 min ; 726 (bp) ,   241 (aa) Go to Linear View
 Product uridylate kinase  
 Note ECK0170:JW0166:b0171  
 Function  
 PID 21239026  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) PYRH_ECOLI ( P0A7E9 ; P29464 )
    -  Protein name RecName: Full=Uridylate kinase; Short=UK; EC=2.7.4.22; AltName: Full=Uridine monophosphate kinase; Short=UMP kinase; Short=UMPK;  
    -  Synonyms  
    -  Gene name Name=pyrH; Synonyms=smbA; OrderedLocusNames=b0171, JW0166;  

 Linear View
View Location
   180.0  –  205.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
        BLAST  
        PSI-BLAST
    nr
         BLAST uridylate kinase [Escherichia coli O157:H7 EDL933]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc pyrH 

MMBR References
Mol Gen Genet. 1994;243(1):9-16.
Multicopy suppressors, mssA and mssB, of an smbA mutation of Escherichia coli.
Yamanaka K, Ogura T, Koonin EV, Niki H, Hiraga S. ( 8190075 )

Sequences
Amino acid
FASTA format
0001 MATNAKPVYK RILLKLSGEA LQGTEGFGID ASILDRMAQE IKELVELGIQ VGVVIGGGNL FRGAGLAKAG 
0071 MNRVVGDHMG MLATVMNGLA MRDALHRAYV NARLMSAIPL NGVCDSYSWA EAISLLRNNR VVILSAGTGN 
0141 PFFTTDSAAC LRGIEIEADV VLKATKVDGV FTADPAKDPT ATMYEQLTYS EVLEKELKVM DLAAFTLARD 
0211 HKLPIRVFNM NKPGALRRVV MGEKEGTLIT E

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TTGTAAATTC AGCTAACCCT TGTGGGGCTG 
-070 CGCTGAAAAG CGACGTACAA TGTCGCTAGT ATTAATTCAT TTCAATCGTT GACAGTCTCA GGAAAGAAAC 
0001 atggctacca atgcaaaacc cgtctataaa cgcattctgc ttaagttgag tggcgaagct ctgcagggca 
0071 ctgaaggctt cggtattgat gcaagcatac tggatcgtat ggctcaggaa atcaaagaac tggttgaact 
0141 gggtattcag gttggtgtgg tgattggtgg gggtaacctg ttccgtggcg ctggtctggc gaaagcgggt 
0211 atgaaccgcg ttgtgggcga ccacatgggg atgctggcga ccgtaatgaa cggcctggca atgcgtgatg 
0281 cactgcaccg cgcctatgtg aacgctcgtc tgatgtccgc tattccattg aatggcgtgt gcgacagcta 
0351 cagctgggca gaagctatca gcctgttgcg caacaaccgt gtggtgatcc tctccgccgg tacaggtaac 
0421 ccgttcttta ccaccgactc agcagcttgc ctgcgtggta tcgaaattga agccgatgtg gtgctgaaag 
0491 caaccaaagt tgacggcgtg tttaccgctg atccggcgaa agatccaacc gcaaccatgt acgagcaact 
0561 gacttacagc gaagtgctgg aaaaagagct gaaagtcatg gacctggcgg ccttcacgct ggctcgtgac 
0631 cataaattac cgattcgtgt tttcaatatg aacaaaccgg gtgcgctgcg ccgtgtggta atgggtgaaa 
0701 aagaagggac tttaatcacg gaataaTTCC CGTGATGGAT AAATAAGGGT AAGATTCCGC GTAAGTATCG 
0771 CGGGGGCGTA AGTCTGGTTA TAAGGCGTTA TTGTTGCAGG CAGTTTGGTC ACGGCC