MG1655
W3110
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Gene Report : hemL
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
Gene. 1992;121(1):127-32.
Cloning and characterization of genes involved in the biosynthesis of delta-aminolevulinic acid in Escherichia coli.
Ikemi M, Murakami K, Hashimoto M, Murooka Y. ( 1427085 )
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  hemL
Related strains
     Strains Search Search strains by gene name:  hemL   Search strains by all related name:  hemL b0154 ECK0153 gsa? JW0150 popC

General information  (Go to Linear View:)
 Gene Name hemL  
 Alternative name b0154,ECK0153,gsa?,JW0150,popC  
 Location, Length 173,602 - 174,882 (  -  ) ;   3.74 min ; 1281 (bp) ,   426 (aa) Go to Linear View
 Product glutamate-1-semialdehyde aminotransferase  
 Note ECK0153:JW0150:b0154; aminomutase  
 Function  
 PID 85674360  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) GSA_ECOLI ( P23893 ; P78277 )
    -  Protein name RecName: Full=Glutamate-1-semialdehyde 2,1-aminomutase; Short=GSA; EC=5.4.3.8; AltName: Full=Glutamate-1-semialdehyde aminotransferase; Short=GSA-AT;  
    -  Synonyms  
    -  Gene name Name=hemL; Synonyms=gsa, popC; OrderedLocusNames=b0154, JW0150;  

 Linear View
View Location
   165.0  –  190.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Glutamate-1-semialdehyde 2,1-aminomutase; Short=GSA; AltName: Full=Glutamate-1-semialdehyde aminotransferase; Short=GSA-AT  
         PSI-BLAST RecName: Full=Glutamate-1-semialdehyde 2,1-aminomutase; Short=GSA; AltName: Full=Glutamate-1-semialdehyde aminotransferase; Short=GSA-AT
    nr
         BLAST glutamate-1-semialdehyde aminotransferase  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc hemL 

Sequences
Amino acid
FASTA format
0001 MSKSENLYSA ARELIPGGVN SPVRAFTGVG GTPLFIEKAD GAYLYDVDGK AYIDYVGSWG PMVLGHNHPA 
0071 IRNAVIEAAE RGLSFGAPTE MEVKMAQLVT ELVPTMDMVR MVNSGTEATM SAIRLARGFT GRDKIIKFEG 
0141 CYHGHADCLL VKAGSGALTL GQPNSPGVPA DFAKYTLTCT YNDLASVRAA FEQYPQEIAC IIVEPVAGNM 
0211 NCVPPLPEFL PGLRALCDEF GALLIIDEVM TGFRVALAGA QDYYGVVPDL TCLGKIIGGG MPVGAFGGRR 
0281 DVMDALAPTG PVYQAGTLSG NPIAMAAGFA CLNEVAQPGV HETLDELTTR LAEGLLEAAE EAGIPLVVNH 
0351 VGGMFGIFFT DAESVTCYQD VMACDVERFK RFFHMMLDEG VYLAPSAFEA GFMSVAHSME DINNTIDAAR 
0421 RVFAKL

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tgcaccagta caagcagcct gatgtttgac 
-070 gagtatttaa cttgttatga ataacataga atagcagcca ttcacttttt ctacgaatca ggaaccctcc 
0001 atgagtaagt ctgaaaatct ttacagcgca gcgcgcgagc tgatccctgg cggtgtgaac tcccctgttc 
0071 gcgcctttac tggcgtgggc ggcactccac tgtttatcga aaaagcggac ggcgcttatc tgtacgatgt 
0141 tgatggcaaa gcctatatcg attatgtcgg ttcctggggg ccgatggtgc tgggccataa ccatccggca 
0211 atccgcaatg ccgtgattga agccgccgag cgtggtttaa gctttggtgc accaaccgaa atggaagtga 
0281 aaatggcgca actggtgacc gaactggtcc cgaccatgga tatggtgcgc atggtgaact ccggcactga 
0351 agcgaccatg agcgccatcc gcctggcccg tggttttacc ggtcgcgaca aaattattaa atttgaaggg 
0421 tgttaccatg gtcacgctga ctgcctgctg gtgaaagccg gttctggcgc actcacgtta ggccagccaa 
0491 actcgccggg cgttccggca gatttcgcca aatatacctt aacctgtact tataatgatc tggcttctgt 
0561 acgcgccgca tttgagcaat acccgcaaga gattgcctgt attatcgtcg agccggtggc aggcaatatg 
0631 aactgtgttc cgccgctgcc agagttcctg ccaggtctgc gcgcgctgtg cgacgaattt ggcgcgttgc 
0701 tgatcatcga tgaagtgatg accggtttcc gcgtagcgct agctggcgca caggattatt acggcgtagt 
0771 gccagattta acctgcctcg gcaaaatcat cggcggtgga atgccggtag gcgcattcgg tggtcgtcgt 
0841 gatgtaatgg atgcgctggc cccgacgggt ccggtctatc aggcgggtac gctttccggt aacccgattg 
0911 cgatggcagc gggtttcgcc tgtctgaatg aagtcgcgca gccgggcgtt cacgaaacgc tggatgagct 
0981 gacaacacgt ctggcagaag gtctgctgga agcggcagaa gaagccggaa ttccgctggt cgttaaccac 
1051 gttggcggca tgttcggtat tttctttacc gacgccgagt ccgtgacgtg ctatcaggat gtgatggcct 
1121 gtgacgtgga acgctttaag cgtttcttcc atatgatgct ggacgaaggt gtttacctgg caccgtcagc 
1191 gtttgaagcg ggctttatgt ccgtggcgca cagcatggaa gatatcaata acaccatcga tgctgcacgt 
1261 cgggtgtttg cgaagttgtg atccagcatg gtttgtcgga tgcggcgtga acgccttatc cgacctacga 
1331 ttcggggccg tttgtaggcc cgataagacg cgccagcgtc gcatcgggca t