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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
mrcB
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Related strains
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Strains Search
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Search strains by gene name:
mrcB
Search strains by all related name:
mrcB b0149 ECK0148 JW0145 pbpF ponB
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General information (Go to Linear View: )
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Gene Name
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mrcB
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Alternative name
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b0149,ECK0148,JW0145,pbpF,ponB
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Location, Length
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164,730 - 167,264
(
+
)
;
3.55
min
;
2535
(bp) ,
844
(aa)
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Product
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fused glycosyl transferase and transpeptidase
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Note
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ECK0148:JW0145:b0149
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Function
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PID
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85674355
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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PBPB_ECOLI
(
P02919
;
P75664
)
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- Protein name
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RecName: Full=Penicillin-binding protein 1B; Short=PBP-1b; Short=PBP1b; AltName: Full=Murein polymerase; Includes: RecName: Full=Penicillin-insensitive transglycosylase; EC=2.4.1.129; AltName: Full=Peptidoglycan glycosyltransferase; AltName: Full=Peptidoglycan TGase; Includes: RecName: Full=Penicillin-sensitive transpeptidase; EC=3.4.-.-; AltName: Full=DD-transpeptidase;
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- Synonyms
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- Gene name
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Name=mrcB; Synonyms=pbpF, ponB; OrderedLocusNames=b0149, JW0145;
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MMBR References
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Eur J Biochem. 1985;147:437-466
The nucleotide sequences of the ponA and ponB genes encoding penicillin-binding proteins 1A and 1B of Escherichia coli K-12.
Broome-Smith, J. K., A. Edelman, S. Yousif, and B. G. Spratt.
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| Sequences |
Amino acid
FASTA format
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0001 MAGNDREPIG RKGKPTRPVK QKVSRRRYED DDDYDDYDDY EDEEPMPRKG KGKGKGRKPR GKRGWLWLLL
0071 KLAIVFAVLI AIYGVYLDQK IRSRIDGKVW QLPAAVYGRM VNLEPDMTIS KNEMVKLLEA TQYRQVSKMT
0141 RPGEFTVQAN SIEMIRRPFD FPDSKEGQVR ARLTFDGDHL ATIVNMENNR QFGFFRLDPR LITMISSPNG
0211 EQRLFVPRSG FPDLLVDTLL ATEDRHFYEH DGISLYSIGR AVLANLTAGR TVQGASTLTQ QLVKNLFLSS
0281 ERSYWRKANE AYMALIMDAR YSKDRILELY MNEVYLGQSG DNEIRGFPLA SLYYFGRPVE ELSLDQQALL
0351 VGMVKGASIY NPWRNPKLAL ERRNLVLRLL QQQQIIDQEL YDMLSARPLG VQPRGGVISP QPAFMQLVRQ
0421 ELQAKLGDKV KDLSGVKIFT TFDSVAQDAA EKAAVEGIPA LKKQRKLSDL ETAIVVVDRF SGEVRAMVGG
0491 SEPQFAGYNR AMQARRSIGS LAKPATYLTA LSQPKIYRLN TWIADAPIAL RQPNGQVWSP QNDDRRYSES
0561 GRVMLVDALT RSMNVPTVNL GMALGLPAVT ETWIKLGVPK DQLHPVPAML LGALNLTPIE VAQAFQTIAS
0631 GGNRAPLSAL RSVIAEDGKV LYQSFPQAER AVPAQAAYLT LWTMQQVVQR GTGRQLGAKY PNLHLAGKTG
0701 TTNNNVDTWF AGIDGSTVTI TWVGRDNNQP TKLYGASGAM SIYQRYLANQ TPTPLNLVPP EDIADMGVDY
0771 DGNFVCSGGM RILPVWTSDP QSLCQQSEMQ QQPSGNPFDQ SSQPQQQPQQ QPAQQEQKDS DGVAGWIKDM
0841 FGSN
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 GGGACCGATC GAGCACAAAT TTTGAGAGAT
-070 ATCTTCTTCT GTCTTGTAAC AGAAGAACAG AAAATCGGGC TTTTGCGCCT GAATATTGCG GAGAAAAAGC
0001 atggccggga atgaccgcga gccaattgga cgcaaaggga aaccgacgcg tccggtcaaa caaaaggtaa
0071 gccgtcgtcg ttacgaagat gacgatgatt acgacgatta tgatgactat gaggatgaag aaccgatgcc
0141 gcgcaaaggt aagggcaaag gcaaagggcg taagcctcgt ggcaaacgcg gctggctatg gctactgcta
0211 aaactggcta tcgtttttgc cgtgctgatc gccatttacg gcgtttatct cgatcaaaaa attcgtagcc
0281 gtattgatgg caaggtctgg caactgcctg cggcagttta tggccgaatg gtcaatcttg agccagacat
0351 gaccatcagc aagaacgaga tggtgaagct gctggaggcg acccagtatc gtcaggtgtc gaaaatgacc
0421 cgtcctggcg aatttaccgt gcaggccaac agcattgaga tgattcgccg tccgtttgat ttcccggaca
0491 gtaaagaagg acaggtgcgc gcgcgtctga cctttgatgg cgatcatctg gcgacgatcg tcaatatgga
0561 gaacaaccgt cagttcggtt tcttccgtct tgatccgcgt ctgatcacca tgatctcttc gccaaacggt
0631 gagcagcgtc tgtttgtgcc gcgcagtggt ttcccggatt tgctggtgga tactttgctg gcgacagaag
0701 accgtcattt ttacgagcat gatggaatca gtctctactc aatcggacgt gcggtgctgg caaacctgac
0771 cgccggacgc acggtacagg gtgcgagtac gctgacgcaa cagctggtga aaaacctgtt cctctccagc
0841 gagcgttctt actggcgtaa agcgaacgaa gcttacatgg cgctgatcat ggacgcgcgt tacagcaaag
0911 accgtattct tgagctgtat atgaacgagg tgtatctcgg tcagagcggc gacaacgaaa tccgcggctt
0981 cccgctggca agcttgtatt actttggtcg cccggtagaa gagctaagcc tcgaccagca ggcgctgtta
1051 gtcggtatgg tgaaaggggc gtccatctac aacccgtggc gtaacccaaa actggcgctg gagcgacgta
1121 atctggtgct gcgtctgctg caacagcaac agattattga tcaagaactc tatgacatgt tgagtgcccg
1191 tccgctgggg gttcagccgc gcggtggggt gatctctcct cagccagcct ttatgcaact ggtgcgtcag
1261 gagctgcagg caaaactggg cgataaggta aaagatctct ccggcgtgaa gatcttcact acctttgact
1331 cggtggccca ggacgcggca gaaaaagccg ccgtggaagg cattccggca ctgaagaaac agcgtaagtt
1401 gagcgatctt gaaactgcga ttgtggtcgt cgaccgcttt agtggtgaag ttcgtgcgat ggtcggaggt
1471 tctgagccgc agtttgcggg ctacaaccgt gcgatgcagg cgcgtcgttc gattggttcc cttgcaaaac
1541 cagcgactta tctgacggcc ttaagccagc cgaaaatcta tcgtctgaat acgtggattg cggatgcgcc
1611 aattgcgctg cgtcagccga atggccaggt ctggtcaccg cagaatgatg accgtcgtta tagcgaaagc
1681 ggcagagtga tgctggtgga tgcgttgacc cgttcgatga acgtgccgac ggtaaatctg gggatggcgc
1751 tggggctgcc tgcggttacg gagacctgga ttaaactggg cgtaccgaaa gatcagttgc atccggttcc
1821 ggcaatgctg ctgggggcgt tgaacttaac gccaatcgaa gtggcgcagg cattccagac catcgccagc
1891 ggtggtaacc gtgcaccgct ttctgcgctg cgttcggtaa tcgcggaaga tggcaaagtg ctgtatcaga
1961 gcttcccgca ggcggaacgc gctgttccgg cgcaggcggc gtatctgaca ctatggacca tgcagcaggt
2031 ggtacaacgc ggtacgggtc gtcagcttgg ggcgaaatac ccgaacctgc atctggcagg gaaaacaggg
2101 actaccaaca ataacgtaga tacctggttt gcgggcattg acggcagcac ggtgaccatc acctgggtcg
2171 gccgtgataa caaccagccg accaaactgt atggtgccag cggggcaatg tcgatttatc agcgttatct
2241 ggctaaccag acgccaacgc cgctgaatct tgttccgcca gaagatattg cagatatggg cgtggactac
2311 gacggcaact ttgtttgcag cggtggcatg cgtatcttgc cggtctggac cagcgatccg caatcgctgt
2381 gccagcagag cgagatgcag cagcagccgt caggcaatcc gtttgatcag tcttctcagc cgcagcaaca
2451 gccgcaacag caacctgctc agcaagagca gaaagacagc gacggtgtag ccggttggat caaggatatg
2521 tttggtagta attaaCATCT AAGCGTGAAA TACCGGATGG CGAGTTGCCA TCCGGTAAAA TAACATCCCA
2591 TCTAAGATAT TAACCCTTTC TTTTCATCTG GTTGTTTATT AACCC
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