MG1655
W3110
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Gene Report : guaC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  guaC
Related strains
     Strains Search Search strains by gene name:  guaC   Search strains by all related name:  guaC b0104 ECK0104 JW0101

General information  (Go to Linear View:)
 Gene Name guaC  
 Alternative name b0104,ECK0104,JW0101  
 Location, Length 113,444 - 114,487 (  +  ) ;   2.44 min ; 1044 (bp) ,   347 (aa) Go to Linear View
 Product GMP reductase  
 Note ECK0104:JW0101:b0104  
 Function  
 PID 85674329  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) GUAC_ECOLI ( P60560 ; P15344; P78048 )
    -  Protein name RecName: Full=GMP reductase; EC=1.7.1.7; AltName: Full=Guanosine 5'-monophosphate oxidoreductase; Short=Guanosine monophosphate reductase;  
    -  Synonyms  
    -  Gene name Name=guaC; OrderedLocusNames=b0104, JW0101;  

 Linear View
View Location
   105.0  –  130.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
         PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=GMP reductase; AltName: Full=Guanosine 5'-monophosphate oxidoreductase; Short=Guanosine monophosphate reductase  
         PSI-BLAST RecName: Full=GMP reductase; AltName: Full=Guanosine 5'-monophosphate oxidoreductase; Short=Guanosine monophosphate reductase
    nr
         BLAST GMP reductase [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc guaC 

MMBR References
J Bacteriol. 1988;170(1):463-7.
Genetic and molecular characterization of the guaC-nadC-aroP region of Escherichia coli K-12.
Roberts RE, Lienhard CI, Gaines CG, Smith JM, Guest JR. ( 3275629 )

Sequences
Amino acid
FASTA format 
0001 MRIEEDLKLG FKDVLIRPKR STLKSRSDVE LERQFTFKHS GQSWSGVPII AANMDTVGTF SMASALASFD 
0071 ILTAVHKHYS VEEWQAFINN SSADVLKHVM VSTGTSDADF EKTKQILDLN PALNFVCIDV ANGYSEHFVQ 
0141 FVAKAREAWP TKTICAGNVV TGEMCEELIL SGADIVKVGI GPGSVCTTRV KTGVGYPQLS AVIECADAAH 
0211 GLGGMIVSDG GCTTPGDVAK AFGGGADFVM LGGMLAGHEE SGGRIVEENG EKFMLFYGMS SESAMKRHVG 
0281 GVAEYRAAEG KTVKLPLRGP VENTARDILG GLRSACTYVG ASRLKELTKR TTFIRVQEQE NRIFNNL
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             AGACAATTTC GCAGTCTTGC GCCGCATTGA 
-070 TTAGTGCGTA TGATAGCGTC ACTGGAGTTG CGCTCTTACC CTTATAGCCA TTAACCCCAG GAATCCGCAC 
0001 atgcgtattg aagaagatct gaagttaggt tttaaagacg ttctcatccg ccctaaacgc tccactctta 
0071 aaagccgttc cgatgttgaa ctggaacgtc aattcacctt caaacattca ggtcagagct ggtccggcgt 
0141 gccgattatc gccgcaaata tggacaccgt aggcacattt tctatggcct ctgcgctggc ttcttttgat 
0211 attttgactg ctgtgcataa acactattct gtcgaagagt ggcaagcgtt tatcaacaat tcttccgctg 
0281 atgtgctgaa acatgtgatg gtttctaccg gtacgtctga tgcggatttc gaaaaaacta aacagattct 
0351 cgacctgaac ccggcattaa acttcgtttg tattgacgtg gcgaatggtt attccgaaca cttcgtgcag 
0421 ttcgttgcga aagcgcgtga agcgtggccg accaaaacca tttgtgctgg taacgtagtg actggtgaaa 
0491 tgtgtgagga gcttatcctc tcaggtgccg atatcgttaa agttggcatt ggcccaggtt ctgtttgtac 
0561 aactcgcgtc aaaacaggcg tcggttatcc gcaactttct gcggtaatcg aatgtgccga tgctgcgcac 
0631 ggtctgggcg gaatgatcgt cagcgatggt ggctgcacca cgccgggcga tgtggcgaaa gcctttggcg 
0701 gcggtgccga tttcgtcatg cttggcggca tgctggcggg ccacgaagag agcggcggtc gcatcgttga 
0771 ggagaacggc gagaaattta tgctgttcta cggcatgagc tccgagtctg cgatgaaacg tcacgttggc 
0841 ggcgttgcgg aatatcgcgc agcagaaggt aaaaccgtta agctgccgct gcgaggcccg gttgaaaata 
0911 ccgcgcgaga tattttgggc ggcctgcgtt cagcttgtac atacgttggg gcttcacgcc tgaaagagct 
0981 gaccaagcgc accacgttta ttcgtgtgca ggaacaagaa aaccgcatct tcaacaacct gtaaTCTCCC 
1051 AACGCTGGCG TGGAGCAACA CGCCAGCGTT ATCCCATCCC ACTCATCGCA TCGCCTAAAT GGAAAATTGG 
1121 CAGATACATT GCCACCACCA GCGT