MG1655
W3110
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Gene Report : purM
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  purM
Related strains
     Strains Search Search strains by gene name:  purM   Search strains by all related name:  purM b2499 ECK2495 JW2484 purG purI

General information  (Go to Linear View:)
 Gene Name purM  
 Alternative name b2499,ECK2495,JW2484,purG,purI  
 Location, Length 2,619,853 - 2,620,890 (  +  ) ;   56.39 min ; 1038 (bp) ,   345 (aa) Go to Linear View
 Product phosphoribosylaminoimidazole synthetase  
 Note ECK2495:JW2484:b2499  
 Function  
 PID 1805559  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) PUR5_ECOLI ( P08178 )
    -  Protein name RecName: Full=Phosphoribosylformylglycinamidine cyclo-ligase; EC=6.3.3.1; AltName: Full=AIRS; AltName: Full=Phosphoribosyl-aminoimidazole synthetase; AltName: Full=AIR synthase;  
    -  Synonyms  
    -  Gene name Name=purM; Synonyms=purG; OrderedLocusNames=b2499, JW2484;  

 Linear View
View Location
   2610.0  –  2635.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
         PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Phosphoribosylformylglycinamidine cyclo-ligase; AltName: Full=AIRS; AltName: Full=Phosphoribosyl-aminoimidazole synthetase; AltName: Full=AIR synthase  
        PSI-BLAST
    nr
         BLAST Chain A, X-Ray Crystal Structure Of Aminoimidazole Ribonucleotide Synthetase  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc purM 

MMBR References
J Biol Chem. 1987;262:10565-10569
Identification and nucleotide sequence of a gene encoding 5'-phosphoribosylglycinamide transformylase in Escherichia coli K12.
Smith, J. M., and H. A. Daum, III.

Sequences
Amino acid
FASTA format 
0001 MTDKTSLSYK DAGVDIDAGN ALVGRIKGVV KKTRRPEVMG GLGGFGALCA LPQKYREPVL VSGTDGVGTK 
0071 LRLAMDLKRH DTIGIDLVAM CVNDLVVQGA EPLFFLDYYA TGKLDVDTAS AVISGIAEGC LQSGCSLVGG 
0141 ETAEMPGMYH GEDYDVAGFC VGVVEKSEII DGSKVSDGDV LIALGSSGPH SNGYSLVRKI LEVSGCDPQT 
0211 TELDGKPLAD HLLAPTRIYV KSVLELIEKV DVHAIAHLTG GGFWENIPRV LPDNTQAVID ESSWQWPEVF 
0281 NWLQTAGNVE HHEMYRTFNC GVGMIIALPA PEVDKALALL NANGENAWKI GIIKASDSEQ RVVIE
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             AAAAGGTTGT GTAAAGCAGT CTCGCAAACG 
-070 TTTGCTTTCC CTGTTAGAAT TGCGCCGAAT TTTATTTTTC TACCGCAAGT AACGCGTGGG GACCCAAGCA 
0001 gtgaccgata aaacctctct tagctacaaa gatgccggtg ttgatattga cgcgggtaat gctctggttg 
0071 gaagaatcaa aggcgtagtg aagaaaacgc gtcgtccgga agtgatgggc ggtctgggcg gcttcggtgc 
0141 gctgtgtgca ttgccgcaaa aatatcgtga acccgtgctg gtttctggca ctgacggcgt aggtaccaag 
0211 ctgcgtctgg caatggactt aaaacgtcac gacaccattg gtattgatct ggtcgccatg tgcgttaatg 
0281 acctggtggt gcaaggtgca gagccgctgt ttttcctcga ctattacgca accggaaaac tggatgttga 
0351 taccgcttca gcggtgatca gcggcattgc ggaaggttgt ctgcaatcag gctgttcact ggtgggtggc 
0421 gaaacggcag aaatgccggg gatgtatcac ggtgaggatt acgatgtcgc gggtttctgc gttggcgtgg 
0491 tagaaaaatc agaaatcatc gacggctcta aagtcagcga cggcgatgtg ctgattgcac tcggttccag 
0561 cggtccacac tcgaacggct attcgctggt gcgcaaaatt cttgaagtca gcggttgtga tccgcaaacc 
0631 accgaacttg atggtaagcc attagccgat catctgctgg caccgacccg catttacgtg aagtcagtgc 
0701 tggagttgat tgaaaaggtc gatgtgcatg ccattgcgca cctgaccggc ggcggcttct gggaaaacat 
0771 tccgcgcgta ttgccagata atactcaggc agtgattgat gaatcttcct ggcagtggcc ggaagtgttc 
0841 aactggctgc aaacggcagg taacgttgag caccatgaaa tgtatcgcac cttcaactgc ggcgtcggga 
0911 tgattattgc cctgcctgct ccggaagtgg acaaagccct cgccctgctc aatgccaacg gtgaaaacgc 
0981 gtggaaaatc ggtatcatca aagcctctga ttccgaacaa cgcgtggtta tcgaataaTG AATATTGTGG 
1051 TGCTTATTTC CGGCAACGGA AGTAATTTAC AGGCAATTAT TGACGCCTGT AAAACCAACA AAATTAAAGG 
1121 CACCGTACGG GCAGTTTT