MG1655
W3110
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Gene Report : nhaR
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  nhaR
Related strains
     Strains Search Search strains by gene name:  nhaR   Search strains by all related name:  nhaR antO b0020 ECK0021 JW0019 yaaB

General information  (Go to Linear View:)
 Gene Name nhaR  
 Alternative name antO,b0020,ECK0021,JW0019,yaaB  
 Location, Length 18,715 - 19,620 (  +  ) ;   0.40 min ; 906 (bp) ,   301 (aa) Go to Linear View
 Product DNA-binding transcriptional activator  
 Note ECK0021:JW0019:b0020  
 Function  
 PID 85674285  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) NHAR_ECOLI ( P0A9G2 ; P10087; P75619; Q2MCH4; Q47409; Q83SR2 )
    -  Protein name RecName: Full=Transcriptional activator protein nhaR; AltName: Full=Na(+)/H(+) antiporter regulatory protein;  
    -  Synonyms  
    -  Gene name Name=nhaR; Synonyms=antO; OrderedLocusNames=b0020, JW0019;  

 Linear View
View Location
   10.0  –  35.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
        BLAST  
        PSI-BLAST
    nr
         BLAST DNA-binding transcriptional activator [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc nhaR 

MMBR References
EMBO J. 1994;13:1981-1989
A single amino acid substitution (Glu134Ala) in NhaR1 increases the inducibility by Na+ of the product of nhaA, a Na+/H+ antiporter gene in Escherichia coli.
Carmel, O., N. Dover, O. Rahav-Manor, P. Dibrov, D. Kirsch, R. Karpel, S. Schuldiner, and E. Padan.

Sequences
Amino acid
FASTA format
0001 MSMSHINYNH LYYFWHVYKE GSVVGAAEAL YLTPQTITGQ IRALEERLQG KLFKRKGRGL EPSELGELVY 
0071 RYADKMFTLS QEMLDIVNYR KESNLLFDVG VADALSKRLV SSVLNAAVVE GEPIHLRCFE STHEMLLEQL 
0141 SQHKLDMIIS DCPIDSTQQE GLFSVRIGEC GVSFWCTNPP PEKPFPACLE ERRLLIPGRR SMLGRKLLNW 
0211 FNSQGLNVEI LGEFDDAALM KAFGAMHNAI FVAPTLYAYD FYADKTVVEI GRVENVMEEY HAIFAERMIQ 
0281 HPAVQRICNT DYSALFSPAV R

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GATACAGCTG GTTACGCGTT CGTTTGCGTC 
-070 CATCAGTTTG ACAGGACGGT TTACCGGGGA GCCATAAACG GCTCCCTTTT CATTGTTATC AGGGAGAGAA 
0001 atgagcatgt ctcatatcaa ttacaaccac ttgtattact tctggcatgt ctataaagaa ggttccgtgg 
0071 ttggcgcagc ggaggcgctt tatttaactc cacaaaccat taccggacag attcgagcgc tggaagagcg 
0141 cctgcaaggc aaattattta aacgcaaggg acgtggtctc gaacccagcg agctgggaga actggtctat 
0211 cgctatgccg ataaaatgtt caccttaagc caggaaatgc tggatattgt gaactatcgc aaagaatcca 
0281 atttattgtt tgacgttggc gtggctgatg cactttccaa acgcctggtc agtagcgtac ttaacgccgc 
0351 agtggtagaa ggcgagccca ttcatcttcg ctgcttcgaa tccacccacg aaatgctgct ggagcaatta 
0421 agtcagcata aactggatat gatcatttct gactgtccga tagactctac gcagcaggaa ggcctgttct 
0491 ccgtgagaat tggcgaatgt ggcgtgagtt tctggtgtac aaatccacca ccagaaaaac cgttcccggc 
0561 ttgtctggaa gaacggcgac ttttgattcc tgggcgacgt tcaatgttag ggcgcaaatt gcttaactgg 
0631 tttaactccc agggattaaa cgtagaaatc ctcggcgagt ttgatgatgc cgctttgatg aaagcttttg 
0701 gtgcgatgca caatgcaatc ttcgttgccc caacgcttta tgcatatgac ttttatgccg ataaaactgt 
0771 cgtagaaatt ggtcgcgtcg agaatgtgat ggaagagtac catgctattt ttgctgagcg gatgattcag 
0841 cacccggcgg tacagcgaat ctgcaatacg gattattctg cgctttttag tccagcggtg cgttaaTCGG 
0911 CAGCTCCCCC AAAGTTAAGG TGGGGGAGAT AGATTAGTTG TACATTACCA CGATTTTGAC TCGGCTCATT 
0981 ATTTGCCCGC TTGAGACATT GTTTCC