MG1655
W3110
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Gene Report : rluA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  rluA
Related strains
     Strains Search Search strains by gene name:  rluA   Search strains by all related name:  rluA b0058 ECK0059 JW0057 yabO

General information  (Go to Linear View:)
 Gene Name rluA  
 Alternative name b0058,ECK0059,JW0057,yabO  
 Location, Length 59,687 - 60,346 (  -  ) ;   1.28 min ; 660 (bp) ,   219 (aa) Go to Linear View
 Product pseudouridine synthase for 23S rRNA (position 746) and tRNAphe(position 32)  
 Note ECK0059:JW0057:b0058  
 Function  
 PID 85674306  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) RLUA_ECOLI ( P0AA37 ; P39219; Q2MCG7; Q83MG7 )
    -  Protein name RecName: Full=Ribosomal large subunit pseudouridine synthase A; EC=5.4.99.-; AltName: Full=rRNA-uridine isomerase A; AltName: Full=rRNA pseudouridylate synthase A;  
    -  Synonyms  
    -  Gene name Name=rluA; Synonyms=yabO; OrderedLocusNames=b0058, JW0057;  

 Linear View
View Location
   50.0  –  75.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Ribosomal large subunit pseudouridine synthase A; AltName: Full=rRNA-uridine isomerase A; AltName: Full=rRNA pseudouridylate synthase A  
        PSI-BLAST
    nr
         BLAST pseudouridine synthase for 23S rRNA  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc rluA 

MMBR References
RNA 1995;1:437-448
A dual-specificity pseudouridine synthase: an Escherichia coli synthase purified and cloned on the basis of its specificity for Psi 746 in 23S RNA is also specific for Psi 32 tRNAPhe.
Wrzesinski, J., K. Nurse, A. Bakin, B. G. Lane, and J. Ofengand.

Sequences
Amino acid
FASTA format
0001 MGMENYNPPQ EPWLVILYQD DHIMVVNKPS GLLSVPGRLE EHKDSVMTRI QRDYPQAESV HRLDMATSGV 
0071 IVVALTKAAE RELKRQFRER EPKKQYVARV WGHPSPAEGL VDLPLICDWP NRPKQKVCYE TGKPAQTEYE 
0141 VVEYAADNTA RVVLKPITGR SHQLRVHMLA LGHPILGDRF YASPEARAMA PRLLLHAEML TITHPAYGNS 
0211 MTFKAPADF

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             agagcaaccg tcagcaggta atggaaagcc 
-070 tggatcaggc aggttggcgt ctggatgccc tgcgtttgat cgttgtaacg catcagtaac ggagccgaaa 
0001 atggggatgg aaaactacaa tccaccgcag gaaccctggt tggttatcct gtatcaggat gaccatatta 
0071 tggtggtcaa caagccgagc ggtttgttgt cagtgccggg tcgtctggaa gagcacaaag acagcgtgat 
0141 gacgcgcatt cagcgtgatt atccgcaggc agaatcggtg catcgtctgg atatggctac cagcggcgtg 
0211 attgtagtgg cgctgaccaa agccgcggag cgggagttaa aacgccagtt ccgcgagcgc gagccgaaaa 
0281 agcagtatgt ggcccgcgtc tgggggcatc catcccccgc agaaggtctg gtggatctgc cgctgatttg 
0351 cgactggcca aaccgcccga aacagaaagt ctgttacgaa acgggtaaac ctgcgcagac ggaatatgaa 
0421 gtggtggagt atgcggcgga taacacggca agagtggtgt taaaaccgat taccgggcgt tcgcatcaat 
0491 tgcgtgtgca tatgctggcg ctgggtcatc cgattctcgg cgatcgtttt tatgcatcac cagaagcgag 
0561 agcgatggca ccacgtttgt tgctacatgc agagatgttg acgattaccc atccggcgta tggcaatagt 
0631 atgacgttta aagcgccagc ggatttttaa cctttcctgt acgtttatac cctcatccta agggctgcct 
0701 cttgtacata aatccccgag tccggggatt ttttgtttct gccaaactgc tttcagttgt