MG1655
W3110
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Gene Report : hisF
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  hisF
Related strains
     Strains Search Search strains by gene name:  hisF   Search strains by all related name:  hisF b2025 ECK2020 JW2007

General information  (Go to Linear View:)
 Gene Name hisF  
 Alternative name b2025,ECK2020,JW2007  
 Location, Length 2,097,981 - 2,098,757 (  +  ) ;   45.15 min ; 777 (bp) ,   258 (aa) Go to Linear View
 Product imidazole glycerol phosphate synthase, catalytic subunit with HisF  
 Note ECK2020:JW2007:b2025  
 Function  
 PID 1736704  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) HIS6_ECOLI ( P60664 ; P10373 )
    -  Protein name RecName: Full=Imidazole glycerol phosphate synthase subunit hisF; EC=4.1.3.-; AltName: Full=IGP synthase cyclase subunit; AltName: Full=IGP synthase subunit hisF; AltName: Full=ImGP synthase subunit hisF; Short=IGPS subunit hisF;  
    -  Synonyms  
    -  Gene name Name=hisF; OrderedLocusNames=b2025, JW2007;  

 Linear View
View Location
   2085.0  –  2110.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
         PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=Imidazole glycerol phosphate synthase subunit hisF; AltName: Full=IGP synthase cyclase subunit; AltName: Full=IGP synthase subunit hisF; AltName: Full=ImGP synthase subunit hisF; Short=IGPS subunit hisF  
         PSI-BLAST RecName: Full=Imidazole glycerol phosphate synthase subunit hisF; AltName: Full=IGP synthase cyclase subunit; AltName: Full=IGP synthase subunit hisF; AltName: Full=ImGP synthase subunit hisF; Short=IGPS subunit hisF
    nr
         BLAST imidazole glycerol phosphate synthase subunit HisF [Escherichia coli O157:H7 EDL933]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc hisF 

MMBR References
J Bacteriol. 1992;174(11):3830-1.
Location of the hisGDCBHAFI operon on the physical map of Escherichia coli.
Alifano P, Carlomagno MS, Bruni CB. ( 1592835 )

Sequences
Amino acid
FASTA format
0001 MLAKRIIPCL DVRDGQVVKG VQFRNHEIIG DIVPLAKRYA EEGADELVFY DITASSDGRV VDKSWVSRVA 
0071 EVIDIPFCVA GGIKSLEDAA KILSFGADKI SINSPALADP TLITRLADRF GVQCIVVGID TWYDAETGKY 
0141 HVNQYTGDES RTRVTQWETL DWVQEVQKRG AGEIVLNMMN QDGVRNGYDL EQLKKVREVC HVPLIASGGA 
0211 GTMEHFLEAF RDADVDGALA ASVFHKQIIN IGELKAYLAT QGVEIRIC

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ACATTGATGA TGTGGCGGCC CTGCGTGGCA 
-070 CTGGTGTGCG CGGCGTAATA GTTGGTCGGG CATTACTGGA AGGTAAATTC ACCGTGAAGG AGGCCATCGC 
0001 atgctggcaa aacgcataat cccatgtctc gacgttcgtg atggtcaggt ggtgaaaggc gtacagtttc 
0071 gcaaccatga aatcattggc gatatcgtgc cgctggcaaa acgctacgct gaagaaggcg ctgacgaact 
0141 ggtgttctac gatatcaccg cttccagcga tggccgtgtg gtagataaaa gctgggtatc tcgcgtggcg 
0211 gaagtgatcg acattccgtt ttgtgtggcg ggtgggatta agtctctgga agatgccgcg aaaattcttt 
0281 cctttggcgc ggataaaatt tccatcaact ctcctgcgct ggcagaccca acattaatta ctcgcctggc 
0351 cgatcgcttt ggcgtgcagt gtattgtggt cggtattgat acctggtacg acgccgaaac cggtaaatat 
0421 catgtgaatc aatataccgg cgatgaaagc cgcacccgcg tcactcaatg ggaaacgctc gactgggtac 
0491 aggaagtgca aaaacgcggt gccggagaaa tcgtcctcaa tatgatgaat caggacggcg tgcgtaacgg 
0561 ttacgacctc gaacaactga aaaaagtgcg tgaagtttgc cacgtcccgc tgattgcctc cggtggcgcg 
0631 ggcaccatgg aacacttcct cgaagccttc cgcgatgccg acgttgacgg cgcgctggca gcttccgtat 
0701 tccacaaaca aataatcaat attggtgaat taaaagcgta cctggcaaca cagggcgtgg agatcaggat 
0771 atgttaaCAG AACAACAACG TCGCGAACTG GACTGGGAAA AAACCGACGG ACTTATGCCG GTGATTGTGC 
0841 AACACGCGGT ATCCGGCGAA GTGCTAATGC TGGGCTA