MG1655
W3110
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Gene Report : holA
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  holA
Related strains
     Strains Search Search strains by gene name:  holA   Search strains by all related name:  holA b0640 ECK0633 JW0635

General information  (Go to Linear View:)
 Gene Name holA  
 Alternative name b0640,ECK0633,JW0635  
 Location, Length 670,996 - 672,027 (  -  ) ;   14.44 min ; 1032 (bp) ,   343 (aa) Go to Linear View
 Product DNA polymerase III, delta subunit  
 Note ECK0633:JW0635:b0640  
 Function  
 PID 1651267  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) HOLA_ECOLI ( P28630 )
    -  Protein name RecName: Full=DNA polymerase III subunit delta; EC=2.7.7.7;  
    -  Synonyms  
    -  Gene name Name=holA; OrderedLocusNames=b0640, JW0635;  

 Linear View
View Location
   660.0  –  685.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=DNA polymerase III subunit delta  
        PSI-BLAST
    nr
         BLAST DNA polymerase III, delta subunit [Escherichia coli str. K-12 substr. MG1655]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc holA 

MMBR References
J Bacteriol. 1992;174:7013-7025
Molecular cloning, sequencing, and overexpression of the structural gene encoding the subunit of Escherichia coli DNA polymerase III holoenzyme.
Carter, J. R., M. A. Franden, R. Aebersold, and C. S. McHenry.

Sequences
Amino acid
FASTA format
0001 MIRLYPEQLR AQLNEGLRAA YLLLGNDPLL LQESQDAVRQ VAAAQGFEEH HTFSIDPNTD WNAIFSLCQA 
0071 MSLFASRQTL LLLLPENGPN AAINEQLLTL TGLLHDDLLL IVRGNKLSKA QENAAWFTAL ANRSVQVTCQ 
0141 TPEQAQLPRW VAARAKQLNL ELDDAANQVL CYCYEGNLLA LAQALERLSL LWPDGKLTLP RVEQAVNDAA 
0211 HFTPFHWVDA LLMGKSKRAL HILQQLRLEG SEPVILLRTL QRELLLLVNL KRQSAHTPLR ALFDKHRVWQ 
0281 NRRGMMGEAL NRLSQTQLRQ AVQLLTRTEL TLKQDYGQSV WAELEGLSLL LCHKPLADVF IDG

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             gcatccgtgc tgcggatatt cgttccgacg 
-070 aagaacagac gtcgaccaca acggatactc cggcaacgcc tgcacgcgtc tccaccacgc tgggtaactg 
0001 atgattcggt tgtacccgga acaactccgc gcgcagctca atgaagggct gcgcgcggcg tatcttttac 
0071 ttggtaacga tcctctgtta ttgcaggaaa gccaggacgc tgttcgtcag gtagctgcgg cacaaggatt 
0141 cgaagaacac cacacttttt ccattgatcc caacactgac tggaatgcga tcttttcgtt atgccaggct 
0211 atgagtctgt ttgccagtcg acaaacgcta ttgctgttgt taccagaaaa cggaccgaat gcggcgatca 
0281 atgagcaact tctcacactc accggacttc tgcatgacga cctgctgttg atcgtccgcg gtaataaatt 
0351 aagcaaagcg caagaaaatg ccgcctggtt tactgcgctt gcgaatcgca gcgtgcaggt gacctgtcag 
0421 acaccggagc aggctcagct tccccgctgg gttgctgcgc gcgcaaaaca gctcaactta gaactggatg 
0491 acgcggcaaa tcaggtgctc tgctactgtt atgaaggtaa cctgctggcg ctggctcagg cactggagcg 
0561 tttatcgctg ctctggccag acggcaaatt gacattaccg cgcgttgaac aggcggtgaa tgatgccgcg 
0631 catttcaccc cttttcattg ggttgatgct ttgttgatgg gaaaaagtaa gcgcgcattg catattcttc 
0701 agcaactgcg tctggaaggc agcgaaccgg ttattttgtt gcgcacatta caacgtgaac tgttgttact 
0771 ggttaacctg aaacgccagt ctgcccatac gccactgcgt gcgttgtttg ataagcatcg ggtatggcag 
0841 aaccgccggg gcatgatggg cgaggcgtta aatcgcttaa gtcagacgca gttacgtcag gccgtgcaac 
0911 tcctgacacg aacggaactc accctcaaac aagattacgg tcagtcagtg tgggcagagc tggaagggtt 
0981 atctcttctg ttgtgccata aacccctggc ggacgtattt atcgacggtt gatatgaaat ctttacaggc 
1051 tctgtttggc ggcacctttg atccggtgca ctatggtcat ctaaaacccg tggaaacgct ggcgaatttg 
1121 attggtctga cg