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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
mraY
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Related strains
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Strains Search
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Search strains by gene name:
mraY
Search strains by all related name:
mraY b0087 ECK0088 JW0085 murX
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General information (Go to Linear View: )
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Gene Name
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mraY
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Alternative name
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b0087,ECK0088,JW0085,murX
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Location, Length
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96,002 - 97,084
(
+
)
;
2.07
min
;
1083
(bp) ,
360
(aa)
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Product
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phospho-N-acetylmuramoyl-pentapeptide transferase
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Note
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ECK0088:JW0085:b0087
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Function
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PID
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21321968
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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MRAY_ECOLI
(
P0A6W3
;
P15876
)
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- Protein name
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RecName: Full=Phospho-N-acetylmuramoyl-pentapeptide-transferase; EC=2.7.8.13; AltName: Full=UDP-MurNAc-pentapeptide phosphotransferase;
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- Synonyms
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- Gene name
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Name=mraY; Synonyms=murX; OrderedLocusNames=b0087, JW0085;
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- Comments
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FUNCTION:First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.
CATALYTIC ACTIVITY:UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.
COFACTOR:Magnesium or manganese.
PATHWAY:Cell wall biogenesis; peptidoglycan biosynthesis.
SUBCELLULAR LOCATION:Cell inner membrane; Multi-pass membrane protein.
SIMILARITY:Belongs to the glycosyltransferase 4 family. MraY subfamily.
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MMBR References
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J Bacteriol. 1991;173(3):1021-6.
The Escherichia coli mraY gene encoding UDP-N-acetylmuramoyl-pentapeptide: undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide transferase.
Ikeda M, Wachi M, Jung HK, Ishino F, Matsuhashi M.
(
1846850
)
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| Sequences |
Amino acid
FASTA format
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0001 MLVWLAEHLV KYYSGFNVFS YLTFRAIVSL LTALFISLWM GPRMIAHLQK LSFGQVVRND GPESHFSKRG
0071 TPTMGGIMIL TAIVISVLLW AYPSNPYVWC VLVVLVGYGV IGFVDDYRKV VRKDTKGLIA RWKYFWMSVI
0141 ALGVAFALYL AGKDTPATQL VVPFFKDVMP QLGLFYILLA YFVIVGTGNA VNLTDGLDGL AIMPTVFVAG
0211 GFALVAWATG NMNFASYLHI PYLRHAGELV IVCTAIVGAG LGFLWFNTYP AQVFMGDVGS LALGGALGII
0281 AVLLRQEFLL VIMGGVFVVE TLSVILQVGS FKLRGQRIFR MAPIHHHYEL KGWPEPRVIV RFWIISLMLV
0351 LIGLATLKVR
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 AATTACTGAT TGCTGAGCAA CAGGTAATTA
-070 CGATTTTAGT TAAGGGTTCA CGTAGTGCCG CCATGGAAGA GGTAGTACGC GCTTTACAGG AGAATGGGAC
0001 atgttagttt ggctggccga acatttggtc aaatattatt ccggctttaa cgtcttttcc tatctgacgt
0071 ttcgcgccat cgtcagcctg ctgaccgcgc tgttcatctc attgtggatg ggcccgcgta tgattgctca
0141 tttgcaaaaa ctttcctttg gtcaggtggt gcgtaacgac ggtcctgaat cacacttcag caagcgcggt
0211 acgccgacca tgggcgggat tatgatcctg acggcgattg tgatctccgt actgctgtgg gcttacccgt
0281 ccaatccgta cgtctggtgc gtgttggtgg tgctggtagg ttacggtgtt attggctttg ttgatgatta
0351 tcgcaaagtg gtgcgtaaag acaccaaagg gttgatcgct cgttggaagt atttctggat gtcggtcatt
0421 gcgctgggtg tcgccttcgc cctgtacctt gccggcaaag acacgcccgc aacgcagctg gtggtcccat
0491 tctttaaaga tgtgatgccg cagctggggc tgttctacat tctgctggct tacttcgtca ttgtgggtac
0561 tggcaacgcg gtaaacctga ccgatggtct cgacggcctg gcaattatgc cgaccgtatt tgtcgccggt
0631 ggttttgcgc tggtggcgtg ggcgaccggc aatatgaact ttgccagcta cttgcatata ccgtatctgc
0701 gacacgccgg ggaactggtt attgtctgta ccgcgatagt cggggcagga ctgggcttcc tgtggtttaa
0771 cacctatccg gcgcaggtct ttatgggcga tgtaggttcg ctggcgttag gtggtgcgtt aggcattatc
0841 gccgtactgc tacgtcagga attcctgctg gtgattatgg ggggcgtgtt cgtggtagaa acgctttctg
0911 tcatcctgca ggtcggctcc tttaaactgc gcggacaacg tattttccgc atggcaccga ttcatcacca
0981 ctatgaactg aaaggctggc cggaaccgcg cgtcattgtg cgtttctgga ttatttcgct gatgctggtt
1051 ctgattggtc tggcaacgct gaaggtacgt taaTCATGGC TGATTATCAG GGTAAAAATG TCGTCATTAT
1121 CGGCCTGGGC CTCACCGGGC TTTCCTGCGT GGACTTTTTC CTCGCTCGCG GTGTGACGCC GCG
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