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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
nagA
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Related strains
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Strains Search
|
Search strains by gene name:
nagA
Search strains by all related name:
nagA b0677 ECK0665 JW0663
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General information (Go to Linear View: )
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Gene Name
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nagA
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Alternative name
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b0677,ECK0665,JW0663
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Location, Length
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702,025 - 703,173
(
-
)
;
15.11
min
;
1149
(bp) ,
382
(aa)
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Product
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N-acetylglucosamine-6-phosphate deacetylase
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Note
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ECK0665:JW0663:b0677
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Function
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PID
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1651280
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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NAGA_ECOLI
(
P0AF18
;
P15300
)
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- Protein name
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RecName: Full=N-acetylglucosamine-6-phosphate deacetylase; EC=3.5.1.25; AltName: Full=GlcNAc 6-P deacetylase;
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- Synonyms
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- Gene name
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Name=nagA; OrderedLocusNames=b0677, JW0663;
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- Comments
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CATALYTIC ACTIVITY:N-acetyl-D-glucosamine 6-phosphate + H(2)O = D-glucosamine 6-phosphate + acetate.
PATHWAY:Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate:step 4/5.
INDUCTION:By N-acetylglucosamine. Induced by low extracellular levels of magnesium via the phoQ/phoP two-component regulatory system.
SIMILARITY:Belongs to the nagA family.
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MMBR References
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Biochem J. 1970;118(1):81-7.
An examination of the inhibitory effects of N-iodoacetylglucosamine on Escherichia coli and isolation of resistant mutants.
White RJ, Kent PW.
(
4919471
)
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| Sequences |
Amino acid
FASTA format
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0001 MYALTQGRIF TGHEFLDDHA VVIADGLIKS VCPVAELPPE IEQRSLNGAI LSPGFIDVQL NGCGGVQFND
0071 TAEAVSVETL EIMQKANEKS GCTNYLPTLI TTSDELMKQG VRVMREYLAK HPNQALGLHL EGPWLNLVKK
0141 GTHNPNFVRK PDAALVDFLC ENADVITKVT LAPEMVPAEV ISKLANAGIV VSAGHSNATL KEAKAGFRAG
0211 ITFATHLYNA MPYITGREPG LAGAILDEAD IYCGIIADGL HVDYANIRNA KRLKGDKLCL VTDATAPAGA
0281 NIEQFIFAGK TIYYRNGLCV DENGTLSGSS LTMIEGVRNL VEHCGIALDE VLRMATLYPA RAIGVEKRLG
0351 TLAAGKVANL TAFTPDFKIT KTIVNGNEVV TQ
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 atttcaatga attagaagca gaaaatatca
-070 aaggtctgta attgttatcc ctgccctggc tccttgctca gggcaatatt ttttaaaatc gggggtcaga
0001 atgtatgcat taacccaggg ccggatcttt accggccacg aatttcttga tgaccacgcg gttgttatcg
0071 ctgatggcct gattaaaagc gtctgtccgg tagcggaact gccgccagag atcgaacaac gttcactgaa
0141 cggggccatt ctctcccccg gttttatcga tgtgcagtta aacggctgcg gcggcgtaca gtttaacgac
0211 accgctgaag cggtcagcgt ggaaacgctg gaaatcatgc agaaagccaa tgagaaatca ggctgtacta
0281 actatctgcc gacgcttatc accaccagcg atgagctgat gaaacagggc gtgcgcgtta tgcgcgagta
0351 cctggcaaaa catccgaatc aggcgttagg tctgcatctg gaaggtccgt ggctgaatct ggtaaaaaaa
0421 ggcacccata atccgaattt tgtgcgtaag cctgatgccg cgctggtcga tttcctgtgt gaaaacgccg
0491 acgtcattac caaagtgacc ctggcaccgg aaatggttcc tgcggaagtc atcagcaaac tggcaaatgc
0561 cgggattgtg gtttctgccg gtcactccaa cgcgacgttg aaagaagcaa aagccggttt ccgcgcgggg
0631 attacctttg ccacccatct gtacaacgcg atgccgtata ttaccggtcg tgaacctggc ctggcgggcg
0701 cgatcctcga cgaagctgac atttattgcg gtattattgc tgatggcctg catgttgatt acgccaacat
0771 tcgcaacgct aaacgtctga aaggcgacaa actgtgtctg gttactgacg ccaccgcgcc agcaggtgcc
0841 aacattgaac agttcatttt tgcgggtaaa acaatatact accgtaacgg actttgtgtg gatgagaacg
0911 gtacgttaag cggttcatcc ttaaccatga ttgaaggcgt gcgtaatctg gtcgaacatt gcggtatcgc
0981 actggatgaa gtgctacgta tggcgacgct ctatccggcg cgtgcgattg gcgttgagaa acgtctcggc
1051 acactcgccg caggtaaagt agccaacctg actgcattca cacctgattt taaaatcacc aagaccatcg
1121 ttaacggtaa cgaggtcgta actcaataag agaaagtatg acaccaggcg gacaagctca gataggtaat
1191 gttgatctcg taaaacagct taacagcgcg gcggtttatc gcctgattga ccagtacgg
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