MG1655
W3110
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Gene Report : fepD
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  fepD
Related strains
     Strains Search Search strains by gene name:  fepD   Search strains by all related name:  fepD b0590 ECK0583 JW0582

General information  (Go to Linear View:)
 Gene Name fepD  
 Alternative name b0590,ECK0583,JW0582  
 Location, Length 620,408 - 621,412 (  -  ) ;   13.35 min ; 1005 (bp) ,   334 (aa) Go to Linear View
 Product iron-enterobactin transporter subunit  
 Note ECK0583:JW0582:b0590; membrane component of ABC superfamily  
 Function  
 PID 85674711  
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) FEPD_ECOLI ( P23876 ; P77097; Q2MBL1 )
    -  Protein name RecName: Full=Ferric enterobactin transport system permease protein fepD;  
    -  Synonyms  
    -  Gene name Name=fepD; OrderedLocusNames=b0590, JW0582;  
    -  Comments
  • FUNCTION:Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane.
  • SUBCELLULAR LOCATION:Cell inner membrane; Multi-pass membrane protein.
  • INDUCTION:Controlled in part by the amount of available iron.
  • SIMILARITY:Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.  

  •  Linear View
    View Location
       610.0  –  635.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP  
        PDB
             PSI-BLAST  
        SWISS-PROT
            BLAST  
            PSI-BLAST
        nr
             BLAST iron-enterobactin transporter subunit [Escherichia coli str. K-12 substr. MG1655]  
    Pfam 27.0   (database updated : 2013-03 )
        Pfam

    Other Cross-Reference
        EcoCyc fepD 

    MMBR References
    Mol Microbiol. 1991;5(6):1415-28.
    Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
    Shea CM, McIntosh MA. ( 1838574 )

    Sequences
    Amino acid
    FASTA format
    0001 MSGSVAVTRA IAVPGLLLLL IIATALSLLI GAKSLPASVV LEAFSGTCQS ADCTIVLDAR LPRTLAGLLA 
    0071 GGALGLAGAL MQTLTRNPLA DPGLLGVNAG ASFAIVLGAA LFGYSSAQEQ LAMAFAGALV ASLIVAFTGS 
    0141 QGGGQLSPVR LTLAGVALAA VLEGLTSGIA LLNPDVYDQL RFWQAGSLDI RNLHTLKVVL IPVLIAGATA 
    0211 LLLSRALNSL SLGSDTATAL GSRVARTQLI GLLAITVLCG SATAIVGPIA FIGLMMPHMA RWLVGADHRW 
    0281 SLPVTLLATP ALLLFADIIG RVIVPGELRV SVVSAFIGAP VLIFLVRRKT RGGA
    
    
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp
    -100                                             tgccatcaaa tattttaaat acctattctt 
    -070 aggctgcaca tgctaacata tccaaataag atcgataacg ataattaatt tcattatcat ggaagttcgt 
    0001 atgtctggtt ctgttgccgt gacacgcgcc attgccgtgc ccggattgct gttattactg attatcgcga 
    0071 cggcattaag cctgctcatt ggggcaaaat cactccccgc ttccgtagtg ctggaggcct tctccggcac 
    0141 ctgccagagc gccgactgca ccatcgtgct cgacgcgcgg ctgccgcgta cccttgccgg tttactggca 
    0211 ggcggcgcgc ttggccttgc cggggcgtta atgcaaaccc tcacccgaaa cccacttgcc gaccccggct 
    0281 tgcttggcgt gaacgccgga gccagctttg ccattgtgct gggtgcggcg ctgtttggtt actcttccgc 
    0351 gcaggaacaa ctggcgatgg ccttcgccgg ggcgctggtg gcctcattga ttgttgcctt taccggcagt 
    0421 cagggcggcg ggcagttaag tccggtgcgt ttaaccctgg cgggcgtggc gctggcggcg gtgctggaag 
    0491 gactgaccag cggcatcgcc ctgcttaatc ctgacgtcta cgatcagttg cgtttctggc aagccggttc 
    0561 gctggatatt cgcaatctac ataccttaaa agtggtgctg atcccggtgc tgatcgccgg agcaactgcg 
    0631 ctattactga gtcgcgcgct gaacagtttg agcctcggca gcgacaccgc gacggcgctg ggcagtcgcg 
    0701 tggcgcgcac acagttgatt ggtctgctgg cgattaccgt gctttgtggt agtgcgacgg caatagttgg 
    0771 cccgattgcc tttattggcc tgatgatgcc gcatatggcg cgttggctgg tgggtgccga tcatcgctgg 
    0841 tcgctgcccg tcacgctact tgctacccct gccctgctgc tgtttgccga tatcatcggg cgggtgattg 
    0911 tgcccggcga actgcgcgtt tctgtggtca gtgcgtttat tggtgcaccg gtgctgatct tcctcgtgcg 
    0981 acgtaaaacg cgaggtggtg catgatttac gtctctcgcc gattactcat cacctgtttg ctgctggttt 
    1051 ccgcctgtgt ggttgcaggt atctggggat tacgcagcgg tgccgtcacg ctgga