MG1655
W3110
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Gene Report : secF
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  secF
Related strains
     Strains Search Search strains by gene name:  secF   Search strains by all related name:  secF b0409 ECK0403 JW0399

General information  (Go to Linear View:)
 Gene Name secF  
 Alternative name b0409,ECK0403,JW0399  
 Location, Length 428,729 - 429,700 (  +  ) ;   9.23 min ; 972 (bp) ,   323 (aa) Go to Linear View
 Product SecYEG protein translocase auxillary subunit  
 Note ECK0403:JW0399:b0409  
 Function  
 PID 85674549  
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) SECF_ECOLI ( P0AG93 ; P19674; P77113; Q2MC17 )
    -  Protein name RecName: Full=Protein-export membrane protein secF;  
    -  Synonyms  
    -  Gene name Name=secF; OrderedLocusNames=b0409, JW0399;  
    -  Comments
  • FUNCTION:Involved in protein export.
  • SUBUNIT:Part of the prokaryotic protein translocation apparatus which comprise secA, secB, secD, secE, secF, secG and secY.
  • SUBCELLULAR LOCATION:Cell inner membrane; Multi-pass membrane protein.
  • SIMILARITY:Belongs to the secD/secF family. SecF subfamily.  

  •  Linear View
    View Location
       420.0  –  445.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP  
        PDB
            PSI-BLAST  
        SWISS-PROT
            BLAST  
            PSI-BLAST
        nr
             BLAST preprotein translocase subunit SecF [Escherichia coli UTI89]  
    Pfam 27.0   (database updated : 2013-03 )
        Pfam

    Other Cross-Reference
        EcoCyc secF 

    MMBR References
    J Bacteriol. 1995;177:4969-4973
    Multicopy suppression of cold-sensitive sec mutations in Escherichia coli.
    Danese, P. N., C. K. Murphy, and T. J. Silhavy.

    Sequences
    Amino acid
    FASTA format
    0001 MAQEYTVEQL NHGRKVYDFM RWDYWAFGIS GLLLIAAIVI MGVRGFNWGL DFTGGTVIEI TLEKPAEIDV 
    0071 MRDALQKAGF EEPMLQNFGS SHDIMVRMPP AEGETGGQVL GSQVLKVINE STNQNAAVKR IEFVGPSVGA 
    0141 DLAQTGAMAL MAALLSILVY VGFRFEWRLA AGVVIALAHD VIITLGILSL FHIEIDLTIV ASLMSVIGYS 
    0211 LNDSIVVSDR IRENFRKIRR GTPYEIFNVS LTQTLHRTLI TSGTTLMVIL MLYLFGGPVL EGFSLTMLIG 
    0281 VSIGTASSIY VASALALKLG MKREHMLQQK VEKEGADQPS ILP
    
    
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp
    -100                                             GCGACGTCGA TGTTTACCGC GATTGTCGGT 
    -070 ACGCGTGCCA TCGTAAACCT GCTATATGGC GGCAAGCGCG TCAAGAAGCT GTCAATCTGA GGAGTGCGAT 
    0001 gtggcacagg aatatactgt tgaacaacta aaccacggcc gtaaagtcta tgactttatg cgctgggact 
    0071 actgggcttt cggcatctct ggtctgctgt taatcgctgc tatcgttatt atgggcgtgc gcggctttaa 
    0141 ctgggggctg gatttcaccg gtggtacggt tattgaaatt acgctcgaaa aaccggctga aattgacgta 
    0211 atgcgtgatg cattgcaaaa agccggtttt gaagagccga tgctgcaaaa ctttggtagc agccatgaca 
    0281 tcatggtccg tatgccgcct gctgaaggcg aaaccggcgg tcaggtgttg ggcagccagg ttctgaaggt 
    0351 gattaacgaa tccaccaatc agaatgcagc agtgaagcgt attgagttcg tcggtccgag cgtgggggca 
    0421 gaccttgcgc aaaccggtgc gatggcgttg atggcagcgc tgctgtctat cctcgtgtac gtaggtttcc 
    0491 gctttgagtg gcgactggcg gcaggggtgg ttattgcgct ggcgcacgac gttatcatta cgctgggtat 
    0561 tttgtcgtta ttccatatcg agattgacct gaccattgtg gcatcgttga tgtcggttat cggttactcg 
    0631 cttaacgaca gtatcgtggt atcggaccgt attcgtgaaa acttccgcaa gatccgtcgc ggtacgcctt 
    0701 acgaaatctt taacgtgtcc ttgacccaga cgctgcaccg taccttgatc acatccggta ctaccttgat 
    0771 ggttatcctg atgctgtacc tcttcggtgg tccggtactg gaaggcttct cgctgaccat gcttatcggt 
    0841 gtttccatcg gtactgcatc ttccatctat gtggcatctg cgttggctct gaaactgggt atgaagcgcg 
    0911 aacacatgtt gcagcagaaa gtggaaaaag aaggggcgga tcagccgtca attctgccgt aaTCAAGTTC 
    0981 CCGTTGATGT TGAAAATCCC GGTCAGAAGA TCGGGATTTT TTTTGATGTA TGGAGATTGC GAAAATCCCC 
    1051 GCATCTTGGG AAACTGCGCG TA