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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
lamB
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Related strains
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Strains Search
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Search strains by gene name:
lamB
Search strains by all related name:
lamB b4036 ECK4028 JW3996 malB malL
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General information (Go to Linear View: )
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Gene Name
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lamB
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Alternative name
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b4036,ECK4028,JW3996,malB,malL
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Location, Length
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4,251,561 - 4,252,901
(
+
)
;
91.50
min
;
1341
(bp) ,
446
(aa)
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Product
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maltose outer membrane porin
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Note
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ECK4028:JW3996:b4036; maltoporin
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Function
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PID
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85676788
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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LAMB_ECOLI
(
P02943
;
Q2M6R8
)
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- Protein name
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RecName: Full=Maltoporin; AltName: Full=Maltose-inducible porin; AltName: Full=Lambda receptor protein; Flags: Precursor;
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- Synonyms
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- Gene name
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Name=lamB; Synonyms=malB; OrderedLocusNames=b4036, JW3996;
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- Comments
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FUNCTION:Involved in the transport of maltose and maltodextrins, indispensable for translocation of dextrins containing more than three glucosyl moieties. A hydrophobic path ("greasy slide") of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda.
SUBUNIT:Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
INTERACTION:P10408:secA; NbExp=2; IntAct=EBI-371309, EBI-543213;
SUBCELLULAR LOCATION:Cell outer membrane; Multi-pass membrane protein.
INDUCTION:By maltose.
SIMILARITY:Belongs to the porin lamB (TC 1.B.3) family.
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MMBR References
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J Bacteriol. 1993;175:1475-1483
Derepression of LamB protein facilitates outer membrane permeation of carbohydrates into Escherichia coli under conditions of nutrient stress.
Death, A., L. Notley, and T. Ferenci.
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| Sequences |
Amino acid
FASTA format
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0001 MMITLRKLPL AVAVAAGVMS AQAMAVDFHG YARSGIGWTG SGGEQQCFQT TGAQSKYRLG NECETYAELK
0071 LGQEVWKEGD KSFYFDTNVA YSVAQQNDWE ATDPAFREAN VQGKNLIEWL PGSTIWAGKR FYQRHDVHMI
0141 DFYYWDISGP GAGLENIDVG FGKLSLAATR SSEAGGSSSF ASNNIYDYTN ETANDVFDVR LAQMEINPGG
0211 TLELGVDYGR ANLRDNYRLV DGASKDGWLF TAEHTQSVLK GFNKFVVQYA TDSMTSQGKG LSQGSGVAFD
0281 NEKFAYNINN NGHMLRILDH GAISMGDNWD MMYVGMYQDI NWDNDNGTKW WTVGIRPMYK WTPIMSTVME
0351 IGYDNVESQR TGDKNNQYKI TLAQQWQAGD SIWSRPAIRV FATYAKWDEK WGYDYTGNAD NNANFGKAVP
0421 ADFNGGSFGR GDSDEWTFGA QMEIWW
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 GTCGACTGCA TAAGGAGCCG GGCGTTTAAG
-070 CACCCCACAA AACACACAAA GCCTGTCACA GGTGATGTGA AAAAAGAAAA GCAATGACTC AGGAGATAGA
0001 atgatgatta ctctgcgcaa acttcctctg gcggttgccg tcgcagcggg cgtaatgtct gctcaggcaa
0071 tggctgttga tttccacggc tatgcacgtt ccggtattgg ttggacaggt agcggcggtg aacaacagtg
0141 tttccagact accggtgctc aaagtaaata ccgtcttggc aacgaatgtg aaacttatgc tgaattaaaa
0211 ttgggtcagg aagtgtggaa agagggcgat aagagcttct atttcgacac taacgtggcc tattccgtcg
0281 cacaacagaa tgactgggaa gctaccgatc cggccttccg tgaagcaaac gtgcagggta aaaacctgat
0351 cgaatggctg ccaggctcca ccatctgggc aggtaagcgc ttctaccaac gtcatgacgt tcatatgatc
0421 gacttctact actgggatat ttctggtcct ggtgccggtc tggaaaacat cgatgttggc ttcggtaaac
0491 tctctctggc agcaacccgc tcctctgaag ctggtggttc ttcctctttc gccagcaaca atatttatga
0561 ctataccaac gaaaccgcga acgacgtttt cgatgtgcgt ttagcgcaga tggaaatcaa cccgggcggc
0631 acattagaac tgggtgtcga ctacggtcgt gccaacttgc gtgataacta tcgtctggtt gatggcgcat
0701 cgaaagacgg ctggttattc actgctgaac atactcagag tgtcctgaag ggctttaaca agtttgttgt
0771 tcagtacgct actgactcga tgacctcgca gggtaaaggg ctgtcgcagg gttctggcgt tgcatttgat
0841 aacgaaaaat ttgcctacaa tatcaacaac aacggtcaca tgctgcgtat cctcgaccac ggtgcgatct
0911 ccatgggcga caactgggac atgatgtacg tgggtatgta ccaggatatc aactgggata acgacaacgg
0981 caccaagtgg tggaccgtcg gtattcgccc gatgtacaag tggacgccaa tcatgagcac cgtgatggaa
1051 atcggctacg acaacgtcga atcccagcgc accggcgaca agaacaatca gtacaaaatt accctcgcac
1121 aacaatggca ggctggcgac agcatctggt cacgcccggc tattcgtgtc ttcgcaacct acgccaagtg
1191 ggatgagaaa tggggttacg actacaccgg taacgctgat aacaacgcga acttcggcaa agccgttcct
1261 gctgatttca acggcggcag cttcggtcgt ggcgacagcg acgagtggac cttcggtgcc cagatggaaa
1331 tctggtggta aTAGCAAAAC CTGGGCCGGA TAAGGCGTTT ACGCCGCATT CGGCAACCAA CGCCTGATGC
1401 GACGCTTGCG CGTCTTATCA GGCCTACAAC GGCTGTCAAA T
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