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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
thrC
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Related strains
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Strains Search
|
Search strains by gene name:
thrC
Search strains by all related name:
thrC b0004 ECK0004 JW0003
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General information (Go to Linear View: )
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Gene Name
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thrC
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Alternative name
|
b0004,ECK0004,JW0003
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Location, Length
|
3,734 - 5,020
(
+
)
;
0.08
min
;
1287
(bp) ,
428
(aa)
|
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Product
|
threonine synthase
|
|
Note
|
ECK0004:JW0003:b0004
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Function
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|
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PID
|
21321894
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
|
THRC_ECOLI
(
P00934
;
Q6LEK8
)
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- Protein name
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RecName: Full=Threonine synthase; EC=4.2.3.1;
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- Synonyms
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- Gene name
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Name=thrC; OrderedLocusNames=b0004, JW0003;
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- Comments
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CATALYTIC ACTIVITY:O-phospho-L-homoserine + H(2)O = L-threonine + phosphate.
COFACTOR:Pyridoxal phosphate.
PATHWAY:Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate:step 5/5.
INTERACTION:P0A6M8:fusA; NbExp=1; IntAct=EBI-1112675, EBI-370503;
SIMILARITY:Belongs to the serine/threonine dehydratase family.
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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PDB
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PSI-BLAST
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SWISS-PROT
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BLAST
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PSI-BLAST
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nr
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BLAST
|
threonine synthase [Escherichia coli str. K-12 substr. MG1655]
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|
Pfam 27.0
(database updated :
2013-03
)
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Pfam
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MMBR References
|
Mol Gen Genet. 1979;175(1):39-44.
Construction and expression of a hybrid plasmid containing the Escherichia coli thrA and thrB genes.
Cossart P, Katinka M, Yaniv M, Saint Girons I, Cohen GN.
(
390305
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MKLYNLKDHN EQVSFAQAVT QGLGKNQGLF FPHDLPEFSL TEIDEMLKLD FVTRSAKILS AFIGDEIPQE
0071 ILEERVRAAF AFPAPVANVE SDVGCLELFH GPTLAFKDFG GRFMAQMLTH IAGDKPVTIL TATSGDTGAA
0141 VAHAFYGLPN VKVVILYPRG KISPLQEKLF CTLGGNIETV AIDGDFDACQ ALVKQAFDDE ELKVALGLNS
0211 ANSINISRLL AQICYYFEAV AQLPQETRNQ LVVSVPSGNF GDLTAGLLAK SLGLPVKRFI AATNVNDTVP
0281 RFLHDGQWSP KATQATLSNA MDVSQPNNWP RVEELFRRKI WQLKELGYAA VDDETTQQTM RELKELGYTS
0351 EPHAAVAYRA LRDQLNPGEY GLFLGTAHPA KFKESVEAIL GETLDLPKEL AERADLPLLS HNLPADFAAL
0421 RKLMMNHQ
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGTTGCCGAC TGGTTGGGTA AGAACTACCT
-070 GCAAAATCAG GAAGGTTTTG TTCATATTTG CCGGCTGGAT ACGGCGGGCG CACGAGTACT GGAAAACTAA
0001 atgaaactct acaatctgaa agatcacaac gagcaggtca gctttgcgca agccgtaacc caggggttgg
0071 gcaaaaatca ggggctgttt tttccgcacg acctgccgga attcagcctg actgaaattg atgagatgct
0141 gaagctggat tttgtcaccc gcagtgcgaa gatcctctcg gcgtttattg gtgatgaaat cccacaggaa
0211 atcctggaag agcgcgtgcg cgcggcgttt gccttcccgg ctccggtcgc caatgttgaa agcgatgtcg
0281 gttgtctgga attgttccac gggccaacgc tggcatttaa agatttcggc ggtcgcttta tggcacaaat
0351 gctgacccat attgcgggtg ataagccagt gaccattctg accgcgacct ccggtgatac cggagcggca
0421 gtggctcatg ctttctacgg tttaccgaat gtgaaagtgg ttatcctcta tccacgaggc aaaatcagtc
0491 cactgcaaga aaaactgttc tgtacattgg gcggcaatat cgaaactgtt gccatcgacg gcgatttcga
0561 tgcctgtcag gcgctggtga agcaggcgtt tgatgatgaa gaactgaaag tggcgctagg gttaaactcg
0631 gctaactcga ttaacatcag ccgtttgctg gcgcagattt gctactactt tgaagctgtt gcgcagctgc
0701 cgcaggagac gcgcaaccag ctggttgtct cggtgccaag cggaaacttc ggcgatttga cggcgggtct
0771 gctggcgaag tcactcggtc tgccggtgaa acgttttatt gctgcgacca acgtgaacga taccgtgcca
0841 cgtttcctgc acgacggtca gtggtcaccc aaagcgactc aggcgacgtt atccaacgcg atggacgtga
0911 gtcagccgaa caactggccg cgtgtggaag agttgttccg ccgcaaaatc tggcaactga aagagctggg
0981 ttatgcagcc gtggatgatg aaaccacgca acagacaatg cgtgagttaa aagaactggg ctacacttcg
1051 gagccgcacg ctgccgtagc ttatcgtgcg ctgcgtgatc agttgaatcc aggcgaatat ggcttgttcc
1121 tcggcaccgc gcatccggcg aaatttaaag agagcgtgga agcgattctc ggtgaaacgt tggatctgcc
1191 aaaagagctg gcagaacgtg ctgatttacc cttgctttca cataatctgc ccgccgattt tgctgcgttg
1261 cgtaaattga tgatgaatca tcagtaaAAT CTATTCATTA TCTCAATCAG GCCGGGTTTG CTTTTATGCA
1331 GCCCGGCTTT TTTATGAAGA AATTATGGAG AAAAATGACA GGGAAAAAGG AGAAATT
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