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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Related gene (MG1655 PEC)
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|
Gene Search
|
Search MG1655 PEC by gene name:
caiC
|
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Related strains
|
|
Strains Search
|
Search strains by gene name:
caiC
Search strains by all related name:
caiC b0037 ECK0038 JW0036 yaaM
|
General information (Go to Linear View: )
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|
Gene Name
|
caiC
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|
Alternative name
|
b0037,ECK0038,JW0036,yaaM
|
|
Location, Length
|
36,271 - 37,839
(
-
)
;
0.78
min
;
1569
(bp) ,
522
(aa)
|
|
Product
|
predicted crotonobetaine CoA ligase:carnitine CoA ligase
|
|
Note
|
ECK0038:JW0036:b0037
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Function
|
|
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PID
|
21321919
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|
SWISS-PROT
(
Show simple
)
|
Entry name(Acc.no)
|
CAIC_ECOLI
(
P31552
;
Q6IU50
)
|
|
- Protein name
|
RecName: Full=Probable crotonobetaine/carnitine-CoA ligase; EC=6.2.1.-;
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- Synonyms
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- Gene name
|
Name=caiC; Synonyms=yaaM; OrderedLocusNames=b0037, JW0036;
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|
- Comments
|
FUNCTION:Could catalyze the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the caiB reaction cycle.
PATHWAY:Amine and polyamine metabolism; carnitine metabolism.
SIMILARITY:Belongs to the ATP-dependent AMP-binding enzyme family.
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Homology Analysis
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BLAST
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Bacteria
|
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GTOP
|
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PDB
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|
PSI-BLAST
|
|
|
SWISS-PROT
|
|
BLAST
|
|
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PSI-BLAST
|
|
|
nr
|
|
BLAST
|
predicted crotonobetaine CoA ligase:carnitine CoA ligase [Escherichia coli str. K-12 substr. W3110]
|
|
Pfam 27.0
(database updated :
2013-03
)
|
|
Pfam
|
|
| Sequences |
Amino acid
FASTA format
|
0001 MDRGAMDIIG GQHLRQMWDD LADVYGHKTA LICESSGGVV NRYSYLELNQ EINRTANLFY TLGIRKGDKV
0071 ALHLDNCPEF IFCWFGLAKI GAIMVPINAR LLCEESAWIL QNSQACLLVT SAQFYPMYQQ IQQEDATQLR
0141 HICLTDVALP ADDGVSSFTQ LKNQQPATLC YAPPLSTDDT AEILFTSGTT SRPKGVVITH YNLRFAGYYS
0211 AWQCALRDDD VYLTVMPAFH IDCQCTAAMA AFSAGATFVL VEKYSARAFW GQVQKYRATV TECIPMMIRT
0281 LMVQPPSAND QQHRLREVMF YLNLSEQEKD AFCERFGVRL LTSYGMTETI VGIIGDRPGD KRRWPSIGRV
0351 GFCYEAEIRD DHNRPLPAGE IGEICIKGIP GKTIFKEYFL NPQATAKVLE ADGWLHTGDT GYRDEEDFFY
0421 FVDRRCNMIK RGGENVSCVE LENIIAAHPK IQDIVVVGIK DSIRDEAIKA FVVLNEGETL SEEEFFRFCE
0491 QNMAKFKVPS YLEIRKDLPR NCSGKIIRKN LK
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 caggagttgg tcagcaaagg tctggccaaa
-070 gttgaggact aaacgcgtgg cgtcagtcgg cttgcctgac tagcgcccgc ccaataacaa acgaacaaaa
0001 atggatagag gtgcaatgga tatcattggc ggacaacatc tacgtcaaat gtgggacgat cttgcggacg
0071 tttacggtca taaaacggcg ctgatttgtg aatccagcgg cggagtcgtt aaccggtata gttatcttga
0141 gttaaatcag gagattaacc gcacggcaaa cctgttttat acgctgggga ttcgcaaagg cgacaaggtt
0211 gcactacatc tcgacaactg cccggaattt atcttttgct ggttcgggct ggcaaaaatt ggcgcgatta
0281 tggtgccgat taacgcccgc ctgttgtgcg aggaaagcgc gtggatcctg caaaatagcc aggcgtgcct
0351 gctggtgacc agtgcgcaat tctatcctat gtatcaacag attcagcagg aagatgccac tcaattgcgg
0421 cacatttgcc tgacagatgt ggcacttccc gctgatgatg gcgtgagttc gtttactcaa ctgaaaaatc
0491 aacaacctgc caccttgtgc tatgcaccgc cgctatcgac tgacgatacg gcggaaattc tcttcacctc
0561 cggcaccacc tcccgaccga aaggtgtggt gattacccat tacaacctgc gcttcgctgg atattactcc
0631 gcctggcagt gtgcactgcg tgacgatgac gtctacctga cggtaatgcc tgcgtttcat atcgattgcc
0701 agtgtactgc ggcgatggcg gcgttttctg ccggggccac ctttgtgctg gtcgagaaat acagcgcccg
0771 cgccttctgg ggacaggtac agaagtaccg cgccaccgtt accgaatgta ttccgatgat gatccgtacg
0841 ttgatggtac agccgccttc agcgaacgat cagcaacacc gcctgcggga agtgatgttt tatctcaact
0911 tgtcggagca ggaaaaagat gcgttttgtg aacgcttcgg cgttcgcttg ctgacgtctt atgggatgac
0981 ggaaaccatt gtgggcatta tcggcgatcg tcctggcgat aaacgacgct ggccgtcgat tggtcgggtg
1051 gggttttgct acgaagcgga gatccgcgac gatcacaatc gcccgctccc ggctggtgag atcggtgaaa
1121 tctgcattaa aggcatacct gggaaaacca tcttcaaaga gtactttctc aacccacaag ccactgcgaa
1191 agtgctggaa gccgatggct ggctgcatac cggcgatacc ggataccgcg acgaagagga ctttttttat
1261 ttcgtcgatc gccgctgcaa tatgattaaa cgtggcggcg agaatgtctc ctgcgtggag ctggaaaata
1331 ttatcgccgc gcacccgaaa attcaggaca tcgtggttgt gggtattaaa gattcgattc gcgatgaagc
1401 catcaaagca tttgtggtgc tgaatgaagg tgaaacattg agcgaagagg aatttttccg cttctgcgaa
1471 caaaatatgg cgaaatttaa agtgccctct tatctggaga tcagaaaaga tctgccacgt aattgctcgg
1541 ggaaaataat tagaaagaat ctgaaataaa tgaaacagca gggaactacc ctgccagcta ataatcacac
1611 tctaaaacaa tatgcatttt ttgcagggat gttgtcgtcc ctgaaaaagc aaaaatgga
|
