MG1655
W3110
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Gene Report : rihC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  rihC
Related strains
     Strains Search Search strains by gene name:  rihC   Search strains by all related name:  rihC b0030 ECK0031 JW0028 yaaF

General information  (Go to Linear View:)
 Gene Name rihC  
 Alternative name b0030,ECK0031,JW0028,yaaF  
 Location, Length 27,293 - 28,207 (  +  ) ;   0.59 min ; 915 (bp) ,   304 (aa) Go to Linear View
 Product ribonucleoside hydrolase 3  
 Note ECK0031:JW0028:b0030  
 Function  
 PID 21321912  
SWISS-PROT  ( Show simple )
  botton Entry name(Acc.no) RIHC_ECOLI ( P22564 )
    -  Protein name RecName: Full=Non-specific ribonucleoside hydrolase rihC; EC=3.2.-.-; AltName: Full=Purine/pyrimidine ribonucleoside hydrolase;  
    -  Synonyms  
    -  Gene name Name=rihC; Synonyms=yaaF; OrderedLocusNames=b0030, JW0028;  
    -  Comments
  • FUNCTION:Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity with decreasing activity in the order uridine, xanthosine, inosine, adenosine, cytidine, guanosine.
  • ENZYME REGULATION:Subject to catabolite repression.
  • MISCELLANEOUS:Strictly specific for ribonucleosides.
  • SIMILARITY:Belongs to the IUNH family. RihC subfamily.  

    •  Linear View
    View Location
       15.0  –  40.0 (KBP)

    Homology Analysis
    BLAST
        Bacteria
             GTOP  
        PDB
             PSI-BLAST  
        SWISS-PROT
             BLAST RecName: Full=Non-specific ribonucleoside hydrolase rihC; AltName: Full=Purine/pyrimidine ribonucleoside hydrolase  
            PSI-BLAST
        nr
             BLAST ribonucleoside hydrolase 3 [Escherichia coli str. K-12 substr. MG1655]  
    Pfam 27.0   (database updated : 2013-03 )
        Pfam

    Other Cross-Reference
        EcoCyc rihC 

    Sequences
    Amino acid
    FASTA format 
    0001 MRLPIFLDTD PGIDDAVAIA AAIFAPELDL QLMTTVAGNV SVEKTTRNAL QLLHFWNAEI PLAQGAAVPL 
0071 VRAPRDAASV HGESGMAGYD FVEHNRKPLG IPAFLAIRDA LMRAPEPVTL VAIGPLTNIA LLLSQCPECK 
0141 PYIRRLVIMG GSAGRGNCTP NAEFNIAADP EAAACVFRSG IEIVMCGLDV TNQAILTPDY LSTLPQLNRT 
0211 GKMLHALFSH YRSGSMQSGL RMHDLCAIAW LVRPDLFTLK PCFVAVETQG EFTSGTTVVD IDGCLGKPAN 
0281 VQVALDLDVK GFQQWVAEVL ALAS
    Nucleotide
    FASTA format

    View sequence out neighbor 100bp 
    -100                                             AAGAGCTGCG TGTCGATATT CGTGAAGTCG 
-070 ATTAAGTCAT TAGCAGCCTA AGTTATGCGA AAATGCCGGT CTTGTTACCG GCATTTTTTA TGGAGAAAAC 
0001 atgcgtttac ctatcttcct cgatactgac cccggcattg acgatgccgt cgccattgcc gccgcgattt 
0071 ttgcacccga actcgacctg caactgatga ccaccgtcgc gggtaatgtc tcggttgaga aaactacccg 
0141 caatgccctg caactgctgc atttctggaa tgcggagatt ccgctcgccc aaggggccgc tgtgccactg 
0211 gtacgcgcac cgcgtgatgc ggcatctgtg cacggcgaat cgggaatggc tggctacgac tttgttgagc 
0281 acaaccgaaa gccgctcggg ataccggcgt ttctggcgat tcgggatgcc ctgatgcgtg caccagagcc 
0351 tgttaccctg gtggccatcg gcccgttaac caatattgcg ctgttacttt cacaatgccc ggaatgcaag 
0421 ccgtatattc gccgtctggt gatcatgggt ggttctgccg gacgcggcaa ctgtacgcca aacgccgagt 
0491 ttaatattgc tgccgatcca gaagctgctg cctgtgtctt ccgcagtggt attgaaatcg tcatgtgcgg 
0561 tttggatgtc accaatcagg caatattaac tcctgactat ctctctacac tgccgcagtt aaaccgtacc 
0631 gggaaaatgc ttcacgccct gtttagccac taccgtagcg gcagtatgca aagcggcttg cgaatgcacg 
0701 atctctgcgc catcgcctgg ctggtgcgcc cggacctgtt cactctcaaa ccctgttttg tggcagtgga 
0771 aactcagggc gaatttacct caggcacgac ggtggttgat atcgacggtt gcctgggcaa gccagccaat 
0841 gtacaggtgg cattggatct ggatgtgaaa ggcttccagc agtgggtggc tgaggtgctg gctctggcgt 
0911 cgtaaCCTGT CACATGTTAT TGGCATGCAG TCATTCATCG ACTCATGCCT TTCACTGATA TCCCTCCCTG 
0981 TTTATCATTA ATTTCTAATT ATCAGCGTTT TTGGC