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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
fkpB
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Related strains
|
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Strains Search
|
Search strains by gene name:
fkpB
Search strains by all related name:
fkpB b0028 ECK0029 JW0026 slpA yaaD
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General information (Go to Linear View: )
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Gene Name
|
fkpB
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Alternative name
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b0028,ECK0029,JW0026,slpA,yaaD
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Location, Length
|
25,826 - 26,275
(
+
)
;
0.56
min
;
450
(bp) ,
149
(aa)
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Product
|
FKBP-type peptidyl-prolyl cis-trans isomerase
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Note
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ECK0029:JW0026:b0028; rotamase
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Function
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PID
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21321910
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
|
FKBX_ECOLI
(
P0AEM0
;
P22563
)
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- Protein name
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RecName: Full=FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase; Short=PPIase; Short=Rotamase; EC=5.2.1.8;
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- Synonyms
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- Gene name
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Name=fkpB; Synonyms=slpA, yaaD; OrderedLocusNames=b0028, JW0026;
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- Comments
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FUNCTION:PPIases accelerate the folding of proteins. Substrate specificity carried out with 'Suc-Ala-Xaa-Pro-Phe-4-nitroanilide', where Xaa is the amino acid tested, was found to be Phe > Leu >> Ile > Lys = Ala > Trp > His >> Gln.
CATALYTIC ACTIVITY:Peptidylproline (omega=180) = peptidylproline (omega=0).
MASS SPECTROMETRY:Mass=15946; Method=Electrospray; Range=2-149; Source=PubMed:9188461;
SIMILARITY:Belongs to the FKBP-type PPIase family.
SIMILARITY:Contains 1 PPIase FKBP-type domain.
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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PDB
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PSI-BLAST
|
Chain A, Solution Structure Of E.Coli Slyd
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SWISS-PROT
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BLAST
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PSI-BLAST
|
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nr
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BLAST
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FKBX-type 16KD peptidyl-prolyl cis-trans isomerase
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Pfam 27.0
(database updated :
2013-03
)
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Pfam
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| Sequences |
Amino acid
FASTA format
|
0001 MSESVQSNSA VLVHFTLKLD DGTTAESTRN NGKPALFRLG DASLSEGLEQ HLLGLKVGDK TTFSLEPDAA
0071 FGVPSPDLIQ YFSRREFMDA GEPEIGAIML FTAMDGSEMP GVIREINGDS ITVDFNHPLA GQTVHFDIEV
0141 LEIDPALEA
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ACGCATCTTA TCCGGCCTAC AGATTGCTGC
-070 GAAATCGTAG GCCGGATAAG GCGTTTACGC CGCATCCGGC AAAAATCCTT AAATATAAGA GCAAACCTGC
0001 atgtctgaat ctgtacagag caatagcgcc gtcctggtgc acttcacgct aaaactcgac gatggcacca
0071 ccgccgagtc tacccgcaac aacggtaaac cggcgctgtt ccgcctgggt gatgcttctc tttctgaagg
0141 gctggagcaa cacctgttgg ggctgaaagt gggcgataaa accaccttct cgttggagcc agatgcggcg
0211 tttggcgtgc cgtcaccgga cctgattcag tacttctccc gccgtgaatt tatggatgca ggcgagccag
0281 aaattggcgc aatcatgctt tttaccgcaa tggatggcag tgagatgcct ggcgtgatcc gcgaaattaa
0351 cggcgactcc attaccgttg atttcaacca tccgctggcc gggcagaccg ttcattttga tattgaagtg
0421 ctggaaatcg atccggcact ggaggcgtaa CATGCAGATC CTGTTGGCCA ACCCGCGTGG TTTTTGTGCC
0491 GGGGTAGACC GCGCTATCAG CATTGTTGAA AACGCGCTGG CCATTTACGG CGCACCGATA
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