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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Related gene (MG1655 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
fhuC
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Related strains
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Strains Search
|
Search strains by gene name:
fhuC
Search strains by all related name:
fhuC b0151 ECK0150 JW0147
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General information (Go to Linear View: )
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Gene Name
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fhuC
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Alternative name
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b0151,ECK0150,JW0147
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Location, Length
|
169,778 - 170,575
(
+
)
;
3.65
min
;
798
(bp) ,
265
(aa)
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Product
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iron-hydroxamate transporter subunit
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Note
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ATP-binding component of ABC superfamily; ECK0150:JW0147:b0151
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Function
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PID
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85674357
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
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FHUC_ECOLI
(
P07821
;
P77548
)
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- Protein name
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RecName: Full=Iron(3+)-hydroxamate import ATP-binding protein fhuC; EC=3.6.3.34; AltName: Full=Iron(III)-hydroxamate import ATP-binding protein fhuC; AltName: Full=Ferrichrome transport ATP-binding protein fhuC; AltName: Full=Ferric hydroxamate uptake protein C;
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- Synonyms
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- Gene name
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Name=fhuC; OrderedLocusNames=b0151, JW0147;
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- Comments
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FUNCTION:Part of the ABC transporter complex fhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY:ATP + H(2)O + iron chelate(Out) = ADP + phosphate + iron chelate(In).
SUBUNIT:The complex is composed of an ATP-binding protein (fhuC), two transmembrane proteins (fhuB) and a solute-binding protein (fhuD).
INTERACTION:P39298:yjfP; NbExp=1; IntAct=EBI-1114151, EBI-1114160;
SUBCELLULAR LOCATION:Cell inner membrane; Peripheral membrane protein.
SIMILARITY:Belongs to the ABC transporter superfamily. Iron (Fe3+)-hydroxamate importer (TC 3.A.1.14.7) family.
SIMILARITY:Contains 1 ABC transporter domain.
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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PDB
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PSI-BLAST
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SWISS-PROT
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BLAST
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PSI-BLAST
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nr
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BLAST
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iron-hydroxamate transporter subunit [Escherichia coli str. K-12 substr. MG1655]
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Pfam 27.0
(database updated :
2013-03
)
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Pfam
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MMBR References
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J Bacteriol. 1987;169(8):3844-9.
fhuC and fhuD genes for iron (III)-ferrichrome transport into Escherichia coli K-12.
Coulton JW, Mason P, Allatt DD.
(
3301821
)
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| Sequences |
Amino acid
FASTA format
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0001 MQEYTNHSDT TFALRNISFR VPGRTLLHPL SLTFPAGKVT GLIGHNGSGK STLLKMLGRH QPPSEGEILL
0071 DAQPLESWSS KAFARKVAYL PQQLPPAEGM TVRELVAIGR YPWHGALGRF GAADREKVEE AISLVGLKPL
0141 AHRLVDSLSG GERQRAWIAM LVAQDSRCLL LDEPTSALDI AHQVDVLSLV HRLSQERGLT VIAVLHDINM
0211 AARYCDYLVA LRGGEMIAQG TPAEIMRGET LEMIYGIPMG ILPHPAGAAP VSFVY
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TCTGGGGCGC AGAACGTCAG GTCGTTGCAA
-070 CCGCAACCTT CCGTTTCTAA TTTCTCTTTT GGGGCACGGA TTTCCGTGCC CATTTCACAA GTTGGCTGTT
0001 atgcaggaat acacgaatca ttccgatacc acttttgcac tgcgtaatat ctcctttcgt gtgcccgggc
0071 gcacgctttt gcatccgctg tcgttaacct ttcctgccgg gaaagtgacc ggtctgattg gtcacaacgg
0141 ttctggtaaa tccactctgc tcaaaatgct tggccgtcat cagccgccgt cggaagggga gattcttctt
0211 gatgcccaac cgctggaaag ctggagcagc aaagcgtttg cccgcaaagt ggcttatttg ccgcagcagc
0281 ttcctccggc agaagggatg accgtgcgtg aactggtggc gattggtcgt tacccgtggc atggcgcgct
0351 ggggcgcttt ggggcggcag atcgcgaaaa agtcgaggaa gctatctcgc tggttggctt aaaaccgctg
0421 gcgcatcggc tggtcgatag tctctctggc ggcgaacgtc agcgggcgtg gatcgccatg ctggtggcgc
0491 aggatagccg ttgtctgttg ctcgacgaac cgacctcggc gctggatatc gcccaccagg ttgatgtgct
0561 gtcgctggtg caccgtttaa gtcaggagcg tggcctgacg gtcattgccg tgttgcacga tatcaatatg
0631 gcggcacgct actgtgatta tctggtcgcc ctgcgcggcg gtgaaatgat tgctcaggga acgcctgcgg
0701 aaattatgcg cggcgaaacc ctcgaaatga tttatggcat cccgatgggt attttgccgc atccggcggg
0771 tgctgcacct gtgagttttg tttattgaTG AGCGGCTTAC CTCTTATTTC GCGCCGTCGA CTGTTAACGG
0841 CGATGGCGCT TTCTCCGTTG TTATGGCAGA TGAATACCGC CCACGCGGCG GCTATTGA
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