MG1655
W3110
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Gene Report : lpxC
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)  
Related gene (MG1655 PEC)
     Gene Search Search MG1655 PEC by gene name:  lpxC
Related strains
     Strains Search Search strains by gene name:  lpxC   Search strains by all related name:  lpxC asmB b0096 ECK0097 envA JW0094

General information  (Go to Linear View:)
 Gene Name lpxC  
 Alternative name asmB,b0096,ECK0097,envA,JW0094  
 Location, Length 106,557 - 107,474 (  +  ) ;   2.29 min ; 918 (bp) ,   305 (aa) Go to Linear View
 Product UDP-3-O-acyl N-acetylglucosamine deacetylase  
 Note ECK0097:JW0094:b0096  
 Function  
 PID 21321977  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) LPXC_ECOLI ( P0A725 ; P07652 )
    -  Protein name RecName: Full=UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; EC=3.5.1.-; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase; AltName: Full=Protein envA;  
    -  Synonyms  
    -  Gene name Name=lpxC; Synonyms=asmB, envA; OrderedLocusNames=b0096, JW0094;  

 Linear View
View Location
   106.557  –  131.557 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP  
    PDB
        PSI-BLAST  
    SWISS-PROT
         BLAST RecName: Full=UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; AltName: Full=UDP-3-O-acyl-GlcNAc deacetylase; AltName: Full=Protein envA  
        PSI-BLAST
    nr
         BLAST UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [Escherichia coli O157:H7 EDL933]  
Pfam 27.0   (database updated : 2013-03 )
    Pfam

Other Cross-Reference
    EcoCyc lpxC 

MMBR References
J Biol Chem. 1995;270:30384-30391
The envA permeability/cell division gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase.
Young, K., L. L. Silver, D. Bramhill, P. Cameron, S. S. Eveland, C. R. Raetz, S. A. Hyland, and M. S. Anderson.

Sequences
Amino acid
FASTA format
0001 MIKQRTLKRI VQATGVGLHT GKKVTLTLRP APANTGVIYR RTDLNPPVDF PADAKSVRDT MLCTCLVNEH 
0071 DVRISTVEHL NAALAGLGID NIVIEVNAPE IPIMDGSAAP FVYLLLDAGI DELNCAKKFV RIKETVRVED 
0141 GDKWAEFKPY NGFSLDFTID FNHPAIDSSN QRYAMNFSAD AFMRQISRAR TFGFMRDIEY LQSRGLCLGG 
0211 SFDCAIVVDD YRVLNEDGLR FEDEFVRHKM LDAIGDLFMC GHNIIGAFTA YKSGHALNNK LLQAVLAKQE 
0281 AWEYVTFQDD AELPLAFKAP SAVLA

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GAATTGACTG GAATTTGGGT TTCGAGGCTC 
-070 TTTGTGCTAA ACTGGCCCGC CGAATGTATA GTACACTTCG GTTGGATAGG TAATTTGGCG AGATAATACG 
0001 atgatcaaac aaaggacact taaacgtatc gttcaggcga cgggtgtcgg tttacatacc ggcaagaaag 
0071 tcaccctgac gttacgccct gcgccggcca acaccggggt catctatcgt cgcaccgact tgaatccacc 
0141 ggtagatttc ccggccgatg ccaaatctgt gcgtgatacc atgctctgta cgtgtctggt caacgagcat 
0211 gatgtacgga tttcaaccgt agagcacctc aatgctgctc tcgcgggctt gggcatcgat aacattgtta 
0281 tcgaagttaa cgcgccggaa atcccgatca tggacggcag cgccgctccg tttgtatacc tgctgcttga 
0351 cgccggtatc gacgagttga actgcgccaa aaaatttgtt cgcatcaaag agactgttcg tgtcgaagat 
0421 ggcgataagt gggctgaatt taagccgtac aatggttttt cgctggattt caccatcgat tttaaccatc 
0491 cggctattga ttccagcaac cagcgctatg cgatgaactt ctccgctgat gcgtttatgc gccagatcag 
0561 ccgtgcgcgt acgttcggtt tcatgcgtga tatcgaatat ctgcagtccc gtggtttgtg cctgggcggc 
0631 agcttcgatt gtgccatcgt tgttgacgat tatcgcgtac tgaacgaaga cggcctgcgt tttgaagacg 
0701 aatttgtgcg tcacaaaatg ctcgatgcga tcggtgactt gttcatgtgt ggtcacaata ttattggtgc 
0771 atttaccgct tataaatccg gtcatgcact gaataacaaa ctgctgcagg ctgtcctggc gaaacaggaa 
0841 gcctgggaat atgtgacctt ccaggacgac gcagaactgc cgttggcctt caaagcgcct tcagctgtac 
0911 tggcataaCG ACATTTATAC TGTCGTATAA AATTCGACTG GCAAATCTGG CACTCTCTCC GGCCAGGTGA 
0981 ACCAGTCGTT TTTTTTTGAA TTTTATAAGA GCTATAAA