MG1655
W3110
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Gene Report : modB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Proc Natl Acad Sci U S A. 1990;87(1):360-3.
Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.
Lejeune P, Danchin A. ( 2404280 )
     Deletion 15 (LD)  ,  DE(pgl-grxA)502  ,  DE(galETK-chlA)  ,  15+dps (LD)  ,  OCR48,49-4 (D)  ,  OCR48,50-8 (LD 15D::Cm) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  modB
Related strains
     Strains Search Search strains by gene name:  modB   Search strains by all related name:  modB b0764 chlJ ECK0753 JW0747

General information  (Go to Linear View:)
 Gene Name modB  
 Alternative name b0764,chlJ,ECK0753,JW0747  
 Location, Length 795,085 - 795,774 (  +  ) ;   17.14 min ; 690 (bp) ,   229 (aa) Go to Linear View
 Product molybdate transporter subunit  
 Operon Name modABC  
 Note molybdate transport permease protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane  
 Function transport; Transport of small molecules: Anions  
 Gene Ontology GO:0005215 ; transporter activity ( modB )
GO:0005515 ; protein binding ( modB )
GO:0005886 ; plasma membrane ( modB )
GO:0006810 ; transport ( modB )
GO:0015098 ; molybdate ion transmembrane transporter activity ( modB )
GO:0015689 ; molybdate ion transport ( modB )
GO:0016020 ; membrane ( modB )
GO:0016021 ; integral to membrane ( modB )
GO:0030151 ; molybdenum ion binding ( modB )
 PID 1786980  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) MODB_ECOLI ( P09834 ; P77537 )
    -  Protein name Molybdenum transport system permease protein modB.  
    -  Synonyms  
    -  Gene name Name=modB; Synonyms=chlJ; OrderedLocusNames=b0764, z0934, ECs0792;  

 Linear View (Whole Mode)
View Location
   785.0  –  810.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP modB (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The 2-Methylisocitrate Lyase (Prpb) From Escherichia Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Molybdenum transport system permease protein modB  
         PSI-BLAST Sulfate transport system permease protein cysW
    nr     (database updated : 2007.02.20 )
         BLAST COG4149: ABC-type molybdate transport system, permease component [Escherichia coli B171]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION    BPD_TRANSP_INN_MEMBR     

Other Cross-Reference
    COG COG4149P 
    EcoCyc modB 

MMBR References
J Bacteriol. 1987;169(5):1911-6.
Cloning and nucleotide sequence of the chlD locus.
Johann S, Hinton SM. ( 3553151 )
J Bacteriol. 1996;178:4310-4312
Molybdenum cofactor biosynthesis in Escherichia coli mod and mog mutants.
Joshi, M. S., J. L. Johnson, and K. V. Rajagopalan.
J Bacteriol. 1995;177:4851-4856
Genetic analysis of the modABCD (molybdate transport) operon of Escherichia coli.
Maupin-Furlow, J. A., J. K. Rosentel, J. H. Lee, U. Deppenmeier, R. P. Gunsalus, and K. T. Shanmugam.
Nucleic Acids Symp Ser. 1995;-34:91-2.
Characterization and transcriptional regulation of the modABCD genes for molybdenum transport in Escherichia coli.
Miyake H, Yabu H, Satoh T, Yamamoto I. ( 8841567 )
J Bacteriol. 1995;177:1023-1029
Regulation of the molybdate transport operon, modABCD, of Escherichia coli in response to molybdate availability.
Rech, S., U. Deppenmeier, and R. P. Gunsalus.
Mol Microbiol. 1992;6(22):3452-4.
Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium.
Shanmugam KT, Stewart V, Gunsalus RP, Boxer DH, Cole JA, Chippaux M, DeMoss JA, Giordano G, Lin EC, Rajagopalan KV. ( 1484496 )
Microbiol Res. 1995;150(4):347-61.
Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.
Walkenhorst HM, Hemschemeier SK, Eichenlaub R. ( 8564363 )

Sequences
Amino acid
FASTA format
0001 MILTDPEWQA VLLSLKVSSL AVLFSLPFGI FFAWLLVRCT FPGKALLDSV LHLPLVLPPV VVGYLLLVSM 
0071 GRRGFIGERL YDWFGITFAF SWRGAVLAAA VMSFPLMVRA IRLALEGVDV KLEQAARTLG AGRWRVFFTI 
0141 TLPLTLPGII VGTVLAFARS LGEFGATITF VSNIPGETRT IPSAMYTLIQ TPGGESGAAR LCIISIALAM 
0211 ISLLISEWLA RISRERAGR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             TGGAAGGGCA TAACAATGCG ACAGTGAAAG 
-070 CATTTTATGA TTATCTGAAG GGACCGCAGG CAGCGGAAAT CTTTAAACGT TACGGATTTA CAATCAAGTA 
0001 atgatactga ccgatccaga atggcaggca gttttattaa gcctgaaagt ttcttccctg gctgtgctgt 
0071 ttagcctgcc gtttgggatc ttttttgcct ggttactggt gcgttgcacg tttccgggca aagctctgct 
0141 cgacagcgta ctgcatctac cgctggtgtt accgcccgtg gtcgtcggtt acttattatt agtttcgatg 
0211 ggacggcgcg gatttatcgg tgaacgtctg tatgactggt ttggtattac cttcgccttt agctggcgcg 
0281 gcgcggttct cgctgccgcc gtcatgtcgt ttccgctgat ggtgcgggca attcgtctgg cgctggaagg 
0351 ggttgatgtc aaactggaac aggccgcaag aacactgggg gccgggcgct ggcgcgtttt ctttactatc 
0421 acgttaccgc tgaccttacc gggaattatt gttggtacgg tactggcttt tgctcgttct ctcggtgagt 
0491 ttggtgcaac catcaccttt gtgtcgaaca ttcctggtga aacgcgaacc attccttctg ccatgtatac 
0561 cctgatccag acccccggcg gggaaagtgg agcggcgaga ctgtgcatta tttctattgc gctggcgatg 
0631 atctccctgt tgatttcaga atggctggcc agaatcagcc gtgaacgggc ggggcgctaa TCATGCTGGA 
0701 ACTGAATTTT TCCCAGACGT TGGGCAACCA TTGCCTGACT ATTAATGAAA CGCTGCCCGC CAATGGCATC 
0771 ACTGCTATCT TTGGCGTCTC