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PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Proc Natl Acad Sci U S A. 1990;87(1):360-3.
Mutations in the bglY gene increase the frequency of spontaneous deletions in Escherichia coli K-12.
Lejeune P, Danchin A.
(
2404280
)
|
|
|
Deletion
|
15
(LD)
,
DE(pgl-grxA)502
,
DE(galETK-chlA)
,
15+dps
(LD)
,
OCR48,49-4
(D)
,
OCR48,50-8 (LD 15D::Cm)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
modE
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
modE
Search strains by all related name:
modE b0761 chlD ECK0750 JW0744 modR
|
General information (Go to Linear View: )
|
|
Gene Name
|
modE
|
|
Alternative name
|
b0761,chlD,ECK0750,JW0744,modR
|
|
Location, Length
|
793,079 - 793,867
(
-
)
;
17.09
min
;
789
(bp) ,
262
(aa)
|
|
Product
|
DNA-binding transcriptional repressor for the molybdenum transport operon modABC
|
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Operon Name
|
modEF
|
|
Note
|
molybdate uptake regulatory protein; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006777 - Mo-molybdopterin cofactor biosynthetic process; GO_process: GO:0006350 - transcription
|
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Function
|
regulator; Transport of small molecules: Anions
|
|
Gene Ontology
|
GO:0003677
;
DNA binding ( modE )
GO:0003700
;
transcription factor activity ( modE )
GO:0005215
;
transporter activity ( modE )
GO:0005524
;
ATP binding ( modE )
GO:0005737
;
cytoplasm ( modE )
GO:0006350
;
transcription ( modE )
GO:0006355
;
regulation of transcription, DNA-dependent ( modE )
GO:0006810
;
transport ( modE )
GO:0015098
;
molybdate ion transmembrane transporter activity ( modE )
GO:0015412
;
molybdate transmembrane-transporting ATPase activity ( modE )
GO:0015689
;
molybdate ion transport ( modE )
GO:0016820
;
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ( modE )
GO:0030151
;
molybdenum ion binding ( modE )
GO:0043190
;
ATP-binding cassette (ABC) transporter complex ( modE )
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PID
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1786976
|
EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
MODE_ECOLI
(
P46930
)
|
|
- Protein name
|
Transcriptional regulator modE.
|
|
- Synonyms
|
|
|
- Gene name
|
OrderedLocusNames=b0761, z0931, ECs0789, SF0543, S0551;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
modE
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Regulator From Escherichia Coli
|
|
SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
|
Transcriptional regulator modE
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PSI-BLAST
|
Methionine import ATP-binding protein metN
|
|
nr
(database updated :
2007.02.20
)
|
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BLAST
|
molybdate uptake regulatory protein [Shigella sonnei Ss046]
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|
Pfam 28.0
(database updated :
2015-05
)
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Pfam
|
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
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MMBR References
|
J Bacteriol. 1996;178:735-744
Repression of the Escherichia coli modABCD (molybdate transport) operon by ModE.
Grunden, A. M., R. M. Ray, J. K. Rosentel, F. G. Healy, and K. T. Shanmugam.
|
FEMS Microbiol Lett. 1996;145(1):117-23.
The Escherichia coli modE gene: effect of modE mutations on molybdate dependent modA expression.
McNicholas PM, Chiang RC, Gunsalus RP.
(
8931336
)
|
Microbiol Res. 1995;150(4):347-61.
Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.
Walkenhorst HM, Hemschemeier SK, Eichenlaub R.
(
8564363
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MQAEILLTLK LQQKLFADPR RISLLKHIAL SGSISQGAKD AGISYKSAWD AINEMNQLSE HILVERATGG
0071 KGGGGAVLTR YGQRLIQLYD LLAQIQQKAF DVLSDDDALP LNSLLAAISR FSLQTSARNQ WFGTITARDH
0141 DDVQQHVDVL LADGKTRLKV AITAQSGARL GLDEGKEVLI LLKAPWVGIT QDEAVAQNAD NQLPGIISHI
0211 ERGAEQCEVL MALPDGQTLC ATVPVNEATS LQQGQNVTAY FNADSVIIAT LC
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 attctaaccg ctaagcacag aaaagcactc
-070 cccttttgtg cggtcagctt tgcgtggcgt tcgttttccg tcacaataag acttttgcca ggacattgtt
0001 atgcaggccg aaatccttct cacccttaag ctccaacaaa aattattcgc cgacccgcgc cgcatttcgc
0071 tactaaaaca cattgcgctt tccggttcca ttagccaggg agcgaaagat gccggtatta gctataaaag
0141 cgcctgggat gccattaacg agatgaatca gttaagtgag catattctgg tcgagcgcgc aacaggcggt
0211 aaaggtggcg gcggcgcagt actgacccgc tatggtcagc gactgattca gctctatgac ttactggcgc
0281 aaatccagca aaaagccttt gatgtgttaa gtgacgatga cgccctgccg ctgaacagcc tgctggccgc
0351 gatctcacgt ttttcactgc aaaccagcgc ccgtaaccag tggttcggta ccatcaccgc ccgcgatcat
0421 gatgacgttc aacagcatgt tgatgtctta ctggctgacg gaaaaacacg cctgaaagtc gcaattaccg
0491 cacaaagcgg cgcgcgtctg gggctggatg aaggcaaaga agtgttgata ttgctaaaag cgccgtgggt
0561 aggtattact caggacgagg cggtcgcgca aaacgctgac aaccaattac cgggtattat tagtcatatt
0631 gagcgcggcg cagagcagtg cgaagtatta atggcgctac ccgacgggca aacactgtgc gccacagtgc
0701 cggtaaatga agcgacttct cttcagcaag gacagaatgt cacggcctac tttaatgccg acagcgtgat
0771 tatcgccacg ctgtgctaag cgtgttgaca atttgttatg aaacacgtat ccctgtcagt aatcgctgca
0841 caaagtggga tataaaatgt catcgttgca aattttgcaa ggcacgttt
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