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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Microbiology. 1998;144 (Pt 12):3297-308.
A factor produced by Escherichia coli K-12 inhibits the growth of E. coli mutants defective in the cytochrome bd quinol oxidase complex: enterochelin rediscovered.
Cook GM, Loder C, Soballe B, Stafford GP, Membrillo-Hernandez J, Poole RK.
(
9884221
)
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Deletion
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OCR44,45-2 (LD 12-1_P/O)
(D)
,
OCR45
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
entA
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Related strains
|
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Strains Search
|
Search strains by gene name:
entA
Search strains by all related name:
entA b0596 ECK0589 JW0588
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General information (Go to Linear View: )
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Gene Name
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entA
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Alternative name
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b0596,ECK0589,JW0588
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Location, Length
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627,774 - 628,520
(
+
)
;
13.53
min
;
747
(bp) ,
248
(aa)
|
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Product
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2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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Operon Name
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entCEBAH
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Note
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2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase, enterochelin biosynthesis; GO_process: GO:0009239 - enterobactin biosynthetic process
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Function
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enzyme; Biosynthesis of cofactors, carriers: Enterochelin
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Gene Ontology
|
GO:0003824
;
catalytic activity ( entA )
GO:0005488
;
binding ( entA )
GO:0005506
;
iron ion binding ( entA )
GO:0006810
;
transport ( entA )
GO:0006811
;
ion transport ( entA )
GO:0006826
;
iron ion transport ( entA )
GO:0008152
;
metabolic process ( entA )
GO:0008667
;
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity ( entA )
GO:0009239
;
enterobactin biosynthetic process ( entA )
GO:0016491
;
oxidoreductase activity ( entA )
|
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PID
|
1786812
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EC number
(KEGG Pathway)
|
1.3.1.28
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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entA
(
EG10259
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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ENTA_ECOLI
(
P15047
;
P77100
)
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- Protein name
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2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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- Synonyms
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EC 1.3.1.28
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- Gene name
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Name=entA; OrderedLocusNames=b0596;
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MMBR References
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J Bacteriol. 1983;156(3):1171-7.
Regulation of enterobactin iron transport in Escherichia coli: characterization of ent::Mu d(Apr lac) operon fusions.
Fleming TP, Nahlik MS, McIntosh MA.
(
6227609
)
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Photochem Photobiol. 1996;64(3):537-41.
Role of enterobactin and intracellular iron in cell lethality during near-UV irradiation in Escherichia coli.
Hoerter J, Pierce A, Troupe C, Epperson J, Eisenstark A.
(
8806229
)
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Gene. 1980;11(3-4):347-57.
Bacteriophage Mu-mediated gene transposition and in vitro cloning of the enterochelin gene cluster of Escherichia coli.
Laird AJ, Ribbons DW, Woodrow GC, Young IG.
(
6260579
)
|
Gene. 1980;11(3-4):359-66.
Tn5 mutagenesis of the enterochelin gene cluster of Escherichia coli.
Laird AJ, Young IG.
(
6260580
)
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J Bacteriol. 1989;171(2):791-8.
Nucleotide sequence of a cluster of Escherichia coli enterobactin biosynthesis genes: identification of entA and purification of its product 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase.
Liu J, Duncan K, Walsh CT.
(
2521622
)
|
J Bacteriol. 1989;171(2):784-90.
Nucleotide sequence and transcriptional organization of the Escherichia coli enterobactin biosynthesis cistrons entB and entA.
Nahlik MS, Brickman TJ, Ozenberger BA, McIntosh MA.
(
2521621
)
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J Bacteriol. 1987;169(9):4163-70.
Cluster of genes controlling synthesis and activation of 2,3-dihydroxybenzoic acid in production of enterobactin in Escherichia coli.
Nahlik MS, Fleming TP, McIntosh MA.
(
3040680
)
|
FEMS Microbiol Lett. 1984;24:77-80.
Molecular cloning of the Escherichia coli K-12 entACGBE genes.
Pickett, C. L., L. Hayes, and C. F. Earhart.
|
FEMS Microbiol Lett. 1989;50(1-2):15-9.
Nucleotide sequence of the Escherichia coli entE gene.
Staab JF, Elkins MF, Earhart CF.
(
2525505
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MDFSGKNVWV TGAGKGIGYA TALAFVEAGA KVTGFDQAFT QEQYPFATEV MDVADAAQVA QVCQRLLAET
0071 ERLDALVNAA GILRMGATDQ LSKEDWQQTF AVNVGGAFNL FQQTMNQFRR QRGGAIVTVA SDAAHTPRIG
0141 MSAYGASKAA LKSLALSVGL ELAGSGVRCN VVSPGSTDTD MQRTLWVSDD AEEQRIRGFG EQFKLGIPLG
0211 KIARPQEIAN TILFLASDLA SHITLQDIVV DGGSTLGA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGCGCTGGCG CAAAGTGCAT GGTGATATCG
-070 ACTTTGTCAT GCTGGCGAAA AACCCGACCA TCGACGCCTG GTGGAAGCTA CTCTCCCGCG AGGTGAAATA
0001 atggatttca gcggtaaaaa tgtctgggta accggcgcag gtaaaggtat cggctacgcc acggcgctgg
0071 cgtttgttga ggcgggagcg aaagttacag gttttgatca agcgttcact caggagcaat atccctttgc
0141 gaccgaagtg atggatgttg ccgacgctgc gcaggtcgcg caagtgtgtc agcgactgtt agctgaaacg
0211 gagcgactgg acgcgctggt caatgcggcg ggaattttac gcatgggcgc gaccgatcag ctcagtaaag
0281 aggactggca gcagactttt gcggttaacg tcggcggtgc gtttaacctg ttccagcaaa ccatgaacca
0351 gtttcgccgt cagcggggcg gggcgattgt cactgtggcg tccgacgccg cgcacacgcc gcgtattggc
0421 atgagtgctt atggcgcatc gaaagcggcg ctgaaaagcc tggcgttgag cgtcgggctg gaactggcgg
0491 gtagcggcgt gcgctgtaat gtggtttcgc ctggctccac cgacaccgat atgcaacgca cgctgtgggt
0561 gagcgatgac gccgaagaac agcgtattcg cggctttggc gagcagttta aactcggcat tccgctgggg
0631 aaaatcgccc gtccacaaga gatcgccaac acgattttgt tcctcgcctc tgacctcgcc agccatatta
0701 ccctacagga tattgtggtc gatggcggct caacgctggg ggcataaGCA TGATCTGGAA ACGCCATTTA
0771 ACGCTCGACG AACTGAACGC CACCAGCGAT AACACAATGG TGGCGCATCT GGGAATTGTG TATACCCGTC
0841 TGGGCGA
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