MG1655
W3110
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Gene Report : fepC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion OCR44,45-2 (LD 12-1_P/O) (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fepC
Related strains
     Strains Search Search strains by gene name:  fepC   Search strains by all related name:  fepC b0588 ECK0581 JW0580

General information  (Go to Linear View:)
 Gene Name fepC  
 Alternative name b0588,ECK0581,JW0580  
 Location, Length 618,607 - 619,422 (  -  ) ;   13.33 min ; 816 (bp) ,   271 (aa) Go to Linear View
 Product iron-enterobactin transporter subunit  
 Operon Name fepDGC  
 Note ATP-binding component of ferric enterobactin transport; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006826 - iron ion transport  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0000166 ; nucleotide binding ( fepC )
GO:0005506 ; iron ion binding ( fepC )
GO:0005524 ; ATP binding ( fepC )
GO:0005886 ; plasma membrane ( fepC )
GO:0006810 ; transport ( fepC )
GO:0006811 ; ion transport ( fepC )
GO:0006826 ; iron ion transport ( fepC )
GO:0016020 ; membrane ( fepC )
GO:0016887 ; ATPase activity ( fepC )
GO:0017111 ; nucleoside-triphosphatase activity ( fepC )
 PID 1786803  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) FEPC_ECOLI ( P23878 ; P75724; P77096 )
    -  Protein name Ferric enterobactin transport ATP-binding protein fepC.  
    -  Synonyms  
    -  Gene name Name=fepC; OrderedLocusNames=b0588;  

 Linear View (Whole Mode)
View Location
   610.0  –  635.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fepC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Atp-Binding Cassette Of Multisugar Transporter From Pyrococcus Horikoshii Ot3 Complexed With Atp  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ferric enterobactin transport ATP-binding protein fepC  
         PSI-BLAST Phosphate import ATP-binding protein pstB
    nr     (database updated : 2007.02.20 )
         BLAST ferric enterobactin transport ATP-binding protein [Escherichia coli]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    ABC_TRANSPORTER     

Other Cross-Reference
    COG COG1120PH 
    EcoCyc fepC 

MMBR References
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA. ( 2956250 )
J Bacteriol. 1989;171(2):775-83.
Nucleotide sequence of Escherichia coli isochorismate synthetase gene entC and evolutionary relationship of isochorismate synthetase and other chorismate-utilizing enzymes.
Ozenberger BA, Brickman TJ, McIntosh MA. ( 2536681 )
J Bacteriol. 1986;166(3):930-6.
Escherichia coli K-12 envelope proteins specifically required for ferrienterobactin uptake.
Pierce JR, Earhart CF. ( 3011753 )
Mol Microbiol. 1991;5(6):1415-28.
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA. ( 1838574 )

Sequences
Amino acid
FASTA format
0001 MTESVARLRG EQLTLGYGKY TVAENLTVEI PDGHFTAIIG PNGCGKSTLL RTLSRLMTPA HGHVWLDGEH 
0071 IQHYASKEVA RRIGLLAQNA TTPGDITVQE LVARGRYPHQ PLFTRWRKED EEAVTKAMQA TGITHLADQS 
0141 VDTLSGGQRQ RAWIAMVLAQ ETAIMLLDEP TTWLDISHQI DLLELLSELN REKGYTLAAV LHDLNQACRY 
0211 ASHLIALREG KIVAQGAPKE IVTAELIERI YGLRCMIIDD PVAGTPLVVP LGRTAPSTAN S

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             aacaactgtt tatgccgtat caacttccgg 
-070 ttggcgtcgt taccgtcagc ctcggcggta tttaccttat cgtcttgtta attcaggagt ctcgcaaaaa 
0001 atgaccgaat cagtagcccg tttgcgcggc gaacagttaa ccctgggata tggcaaatat accgttgcgg 
0071 aaaatctgac tgtagaaata cctgatggtc acttcacggc aattatcggg ccaaatggct gcggtaaatc 
0141 cacgttactg cgtaccttaa gccgcctgat gacgcctgct catgggcatg tctggctgga tggcgagcac 
0211 attcaacatt acgccagtaa agaggttgca cgccggattg gtctgttggc gcaaaatgct accacgccgg 
0281 gcgatatcac cgtgcaggag ctggtggcgc gtggacgtta tccgcatcaa ccgctgttta cccgctggcg 
0351 caaagaggat gaagaagcgg taacgaaagc aatgcaggcc acgggaataa ctcatctggc agatcaaagc 
0421 gtggataccc tttctggcgg acaacgccag cgagcgtgga tcgcgatggt gctggcccag gaaacggcaa 
0491 ttatgctgct cgacgaaccc acgacctggc tggatatcag tcatcagatt gatttgctgg agttgttaag 
0561 cgaactgaac cgcgaaaaag gctataccct ggcggcggtg ctgcacgatc ttaatcaggc ctgtcgttac 
0631 gccagccatt tgattgcatt gcgggaaggg aaaattgttg ctcagggagc gccgaaggag attgtcactg 
0701 ctgaactgat tgagcgcatt tatggtctgc gctgcatgat cattgacgat ccagttgccg gaacgccgct 
0771 tgtggtgccg ctcggacgaa cggcaccttc aaccgcaaat agttaaacta agtggtctgc catcatggca 
0841 tcctgttttc tggatgccat cgcatagcgc aacagcacgc caccacaagc caccatcccg ccgatcaacg 
0911 cggaaa