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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR41
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
mdlB
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Related strains
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Strains Search
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Search strains by gene name:
mdlB
Search strains by all related name:
mdlB b0448 b0449 ECK0443 JW5061 mdl o590 o593
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General information (Go to Linear View: )
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Gene Name
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mdlB
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Alternative name
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b0448,b0449,ECK0443,JW5061,mdl,o590,o593
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Location, Length
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469,860 - 471,641
(
+
)
;
10.13
min
;
1782
(bp) ,
593
(aa)
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Product
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fused predicted multidrug transporter subunits of ABC superfamily: ATP-binding components
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Operon Name
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mdlAB
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Note
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GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
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Function
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Gene Ontology
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GO:0000166
;
nucleotide binding ( mdlB )
GO:0005524
;
ATP binding ( mdlB )
GO:0005886
;
plasma membrane ( mdlB )
GO:0006810
;
transport ( mdlB )
GO:0008559
;
xenobiotic-transporting ATPase activity ( mdlB )
GO:0016020
;
membrane ( mdlB )
GO:0016021
;
integral to membrane ( mdlB )
GO:0016787
;
hydrolase activity ( mdlB )
GO:0016887
;
ATPase activity ( mdlB )
GO:0017111
;
nucleoside-triphosphatase activity ( mdlB )
GO:0042626
;
ATPase activity, coupled to transmembrane movement of substances ( mdlB )
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PID
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1786654
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
1
more]
)
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Entry name(Acc.no)
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MDLB_ECOLI
(
P75706
;
P30751; P77117
)
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- Protein name
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Multidrug resistance-like ATP-binding protein mdlB.
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- Synonyms
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- Gene name
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OrderedLocusNames=b0449, c0566, z0559, ECs0503;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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mdlB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain A, Multidrug Abc Transporter Sav1866
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Multidrug resistance-like ATP-binding protein mdlB
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PSI-BLAST
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Lipid A export ATP-binding/permease protein msbA
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nr
(database updated :
2007.02.20
)
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BLAST
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multidrug resistance-like ATP-binding protein Mdl [Escherichia coli]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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| Sequences |
Amino acid
FASTA format
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0001 MRSFSQLWPT LKRLLAYGSP WRKPLGIAVL MMWVAAAAEV SGPLLISYFI DNMVAKNNLP LKVVAGLAAA
0071 YVGLQLFAAG LHYAQSLLFN RAAVGVVQQL RTDVMDAALR QPLSEFDTQP VGQVISRVTN DTEVIRDLYV
0141 TVVATVLRSA ALVGAMLVAM FSLDWRMALV AIMIFPVVLV VMVIYQRYST PIVRRVRAYL ADINDGFNEI
0211 INGMSVIQQF RQQARFGERM GEASRSHYMA RMQTLRLDGF LLRPLLSLFS SLILCGLLML FGFSASGTIE
0281 VGVLYAFISY LGRLNEPLIE LTTQQAMLQQ AVVAGERVFE LMDGPRQQYG NDDRPLQSGT IEVDNVSFAY
0351 RDDNLVLKNI NLSVPSRNFV ALVGHTGSGK STLASLLMGY YPLTEGEIRL DGRPLSSLSH SALRQGVAMV
0421 QQDPVVLADT FLANVTLGRD ISEERVWQAL ETVQLAELAR SMSDGIYTPL GEQGNNLSVG QKQLLALARV
0491 LVETPQILIL DEATASIDSG TEQAIQHALA AVREHTTLVV IAHRLSTIVD ADTILVLHRG QAVEQGTHQQ
0561 LLAAQGRYWQ MYQLQLAGEE LAASVREEES LSA
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GTGCTGGCAC AACAAAGCGG CTGGTATCGC
-070 GATATGTATC GCTATCAACA ACTGGAGGCG GCGCTCGACG ACGCTCCGGA AAATCGCGAG GAGGCCGTCG
0001 atgcgtagtt ttagccaact gtggccgact ctcaagcgcc tgttagcgta cggttcgccg tggcgtaaac
0071 cgctggggat tgcggtcctg atgatgtggg ttgcggcggc ggcagaagtc agtgggccgc tgcttatcag
0141 ctattttatc gacaatatgg tagcgaaaaa taacctgccg ttgaaagtgg ttgcagggct ggctgcggcg
0211 tatgttgggc tgcaactgtt tgccgccggg ctacattacg cgcagtcgct gctgtttaat cgggcggcag
0281 taggcgtagt gcaacagttg cgtaccgacg tgatggatgc tgcgttacgc cagccattaa gcgagtttga
0351 tacccaaccc gtcgggcagg tgatttcccg cgtcactaat gacactgaag tgatccgcga tctctacgtt
0421 accgtagtgg caactgtcct gcgcagtgcc gcgctggtgg gcgcgatgct ggtggcgatg ttcagcctcg
0491 actggcgaat ggcactggtg gcgataatga ttttcccggt ggtgctggtg gtaatggtga tataccagcg
0561 ttacagcacg ccgattgtcc gtcgtgtgcg cgcctatttg gcggatatca acgacggctt taacgaaatc
0631 atcaatggca tgagcgttat ccagcagttt cgtcagcagg cgcgatttgg cgaacgtatg ggggaggcca
0701 gtcgttcaca ctatatggcg aggatgcaaa ccctgcgcct cgacggtttt ctgctgcgtc cgctgctgag
0771 tctgttttca tcgctcattc tttgtggctt gttgatgctg tttggcttct ccgccagcgg caccattgaa
0841 gtgggcgtgc tgtatgcgtt tatcagctat cttgggcgac ttaacgaacc attaatcgaa ctgaccacgc
0911 aacaggcgat gctgcaacag gctgttgttg ctggtgagcg cgtgtttgaa ctgatggacg gaccgcgcca
0981 gcaatatggc aatgatgatc gcccgttaca gagtggcacc atcgaagtcg ataacgtgtc atttgcttat
1051 cgcgatgaca atctggtgct aaagaacatt aatctctctg tgccttcgcg caattttgtg gcgctggtcg
1121 ggcataccgg cagtggcaaa agcaccctcg ccagtttatt gatgggctat tacccgctaa cggaaggtga
1191 gattcgcctt gatggtcgtc cattaagttc gctaagtcac agcgcgctgc gccagggcgt ggcaatggtg
1261 cagcaagatc cggtggtgct ggcggatacc ttcctcgcca acgtgacgct ggggcgggat atctccgaag
1331 aacgcgtctg gcaggcgctg gaaaccgtgc aactggcgga gctggcgcgt agcatgagcg acggtattta
1401 cacgccgctg ggcgagcagg ggaataatct ctcagttggg caaaagcaac tgctggcact ggcgcgcgtg
1471 ctggtcgaga cgccgcaaat cctgatcctt gatgaggcaa ccgccagcat tgactccggt actgaacagg
1541 cgattcaaca tgctctggcg gcggtgcgtg aacataccac gctggtagtg attgctcacc gcttatcgac
1611 cattgttgat gccgacacca ttctggtgct tcatcgtggg caagccgtgg agcagggcac tcaccagcaa
1681 ctgctggcgg cccagggacg ctactggcag atgtatcaac tgcaacttgc gggcgaagag ctggcagcca
1751 gcgtgcgtga agaggaatca ttgagcgcct gaATAGCGCA ATATTTCATC GTTGGTGCAA AAATGTAACG
1821 CACTGTGCAC TGTCATAGTG CGTTTTCATT TTCAAACTTC TTAACTTCCT GCTCTCTTTC TC
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