|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
1
(LD)
,
OCR20,24-1 (LD 1-1_CRS)
(D)
,
OCR20,24-2 (LD 1-1_P/O)
(D)
,
OCR23
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
iadA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
iadA
Search strains by all related name:
iadA b4328 ECK4319 f390a JW4291 yjiF
|
General information (Go to Linear View: )
|
|
Gene Name
|
iadA
|
|
Alternative name
|
b4328,ECK4319,f390a,JW4291,yjiF
|
|
Location, Length
|
4,556,377 - 4,557,549
(
-
)
;
98.20
min
;
1173
(bp) ,
390
(aa)
|
|
Product
|
isoaspartyl dipeptidase
|
|
Operon Name
|
yjiHG-iadA
|
|
Note
|
|
|
Function
|
enzyme; Degradation of proteins, peptides, glyco
|
|
Gene Ontology
|
GO:0005737
;
cytoplasm ( iadA )
GO:0008233
;
peptidase activity ( iadA )
GO:0008237
;
metallopeptidase activity ( iadA )
GO:0016787
;
hydrolase activity ( iadA )
GO:0016810
;
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ( iadA )
|
|
PID
|
1790784
|
EC number
(KEGG Pathway)
|
3.4.19.5
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
iadA
(
EG12567
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
IADA_ECOLI
(
P39377
)
|
|
- Protein name
|
Isoaspartyl dipeptidase
|
|
- Synonyms
|
EC 3.4.19.-
|
|
- Gene name
|
Name=iadA; OrderedLocusNames=b4328;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
iadA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Escherichia Coli Isoaspartyl Dipeptidase Mutant D285n Complexed With Beta- Aspartylhistidine
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Isoaspartyl dipeptidase
|
|
PSI-BLAST
|
Urease alpha subunit
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
isoaspartyl dipeptidase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
LEUCINE_ZIPPER
|
|
MMBR References
|
J Biol Chem. 1995;270:4076-4087
Purification and characterization of an isoaspartyl dipeptidase from Escherichia coli.
Gary, J. D., and S. Clarke.
|
| Sequences |
Amino acid
FASTA format
|
0001 MIDYTAAGFT LLQGAHLYAP EDRGICDVLV ANGKIIAVAS NIPSDIVPNC TVVDLSGQIL CPGFIDQHVH
0071 LIGGGGEAGP TTRTPEVALS RLTEAGVTSV VGLLGTDSIS RHPESLLAKT RALNEEGISA WMLTGAYHVP
0141 SRTITGSVEK DVAIIDRVIG VKCAISDHRS AAPDVYHLAN MAAESRVGGL LGGKPGVTVF HMGDSKKALQ
0211 PIYDLLENCD VPISKLLPTH VNRNVPLFEQ ALEFARKGGT IDITSSIDEP VAPAEGIARA VQAGIPLARV
0281 TLSSDGNGSQ PFFDDEGNLT HIGVAGFETL LETVQVLVKD YDFSISDALR PLTSSVAGFL NLTGKGEILP
0351 GNDADLLVMT PELRIEQVYA RGKLMVKDGK ACVKGTFETA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agtgaatgcc aaatattacc cgcatatcat
-070 tacggtctgc gtgattaacg cattgctgtc gatctgggtt atgcagctta ttgtttaaca aggagttacc
0001 atgattgatt ataccgcagc cggttttacc ctgctgcagg gagcgcattt gtatgcgccg gaagatcggg
0071 gaatttgcga tgtcctcgtc gctaacggca aaattatcgc cgttgccagc aatatccctt ctgacattgt
0141 accgaactgc acggttgtcg atctcagtgg gcagatcctc tgcccaggtt ttattgatca acacgtccat
0211 ttgattggcg gtggcggcga agcaggtccc acgacgcgca cgccggaagt ggcgctaagt cgcctgacgg
0281 aagcgggcgt cacgtcagtg gttggtctgc tgggcaccga ctctatctct cgccacccgg aatccctgct
0351 cgccaagacc cgtgcgctca atgaagaagg catcagcgcc tggatgctga ccggcgctta tcatgtccct
0421 tcccgcacca ttacgggttc cgtggaaaaa gacgtggcga ttatcgatcg tgtgattggc gtgaaatgcg
0491 ccatctctga tcaccgttct gccgcaccgg acgtttatca cctggccaat atggcggcag aatcccgcgt
0561 tggcggtttg ctcggcggta aacctggcgt caccgtgttc cacatgggcg acagtaaaaa ggcgttacag
0631 cctatttatg acctgctgga aaactgcgat gtgccgatca gcaagctgct gccgacccac gttaaccgca
0701 acgtaccgtt gtttgagcag gcgctggagt tcgcgcgcaa aggcggcacc atcgatatca ccagcagcat
0771 tgacgaaccg gtcgcccctg ccgaaggtat tgcccgcgcc gttcaggcgg gtattccgct ggcacgcgtc
0841 accctcagct ccgacggcaa cggtagccag ccgttcttcg atgacgaagg gaatttaacc catatcggtg
0911 ttgccggttt tgaaacgttg ctggaaaccg tgcaggtgct ggtcaaagac tatgatttca gtatcagcga
0981 tgccctgcgc ccgctcacca gtagcgtagc cggtttcctt aacctgaccg ggaaaggcga aattctgcca
1051 ggcaatgatg ctgacttgct ggtcatgacg ccagaactgc gcattgagca ggtatacgct cgcggcaaac
1121 tgatggtcaa agacggcaaa gcctgcgtga aaggaacgtt tgaaacggct taaacggttg tcagccgccc
1191 gaatggacgt agaatgcccg caagggcggc tgacagagta aaacgtaatg gatgactgtg gtgcgatttt
1261 gcataatatt gaa
|
