MG1655
W3110
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Gene Report : fecC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 1989;171(5):2626-33.
Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
     Deletion 1 (LD)  ,  OCR20,24-1 (LD 1-1_CRS) (D)  ,  OCR20,24-2 (LD 1-1_P/O) (D)  ,  OCR21 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fecC
Related strains
     Strains Search Search strains by gene name:  fecC   Search strains by all related name:  fecC b4289 ECK4279 f332 JW4249

General information  (Go to Linear View:)
 Gene Name fecC  
 Alternative name b4289,ECK4279,f332,JW4249  
 Location, Length 4,510,434 - 4,511,432 (  -  ) ;   97.21 min ; 999 (bp) ,   332 (aa) Go to Linear View
 Product KpLE2 phage-like element; iron-dicitrate transporter subunit  
 Operon Name fecABCDE  
 Note citrate-dependent iron(III) transport protein, cytosolic; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006826 - iron ion transport  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0005215 ; transporter activity ( fecC )
GO:0005506 ; iron ion binding ( fecC )
GO:0005886 ; plasma membrane ( fecC )
GO:0006810 ; transport ( fecC )
GO:0006811 ; ion transport ( fecC )
GO:0006826 ; iron ion transport ( fecC )
GO:0016020 ; membrane ( fecC )
GO:0016021 ; integral to membrane ( fecC )
 PID 1790741  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) FECC_ECOLI ( P15030 )
    -  Protein name Iron(III) dicitrate transport system permease protein fecC.  
    -  Synonyms  
    -  Gene name Name=fecC; OrderedLocusNames=b4289;  

 Linear View (Whole Mode)
View Location
   4500.0  –  4525.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fecC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, An Inward-Facing Conformation Of A Putative Metal-Chelate Type Abc Transporter.  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Iron  
         PSI-BLAST Putative ABC transporter permease protein MJ0087
    nr     (database updated : 2007.02.20 )
         BLAST KpLE2 phage-like element; iron-dicitrate transporter subunit [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CK2_PHOSPHO_SITE    MYRISTYL    PROKAR_LIPOPROTEIN    LEUCINE_ZIPPER     

Other Cross-Reference
    COG COG0609P 
    EcoCyc fecC 

MMBR References
J Bacteriol. 1989;171(5):2626-33.
Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
J Bacteriol. 1990;172(12):6749-58.
Novel two-component transmembrane transcription control: regulation of iron dicitrate transport in Escherichia coli K-12.
Van Hove B, Staudenmaier H, Braun V. ( 2254251 )
J Bacteriol. 1992;174(11):3838-9.
Localization of the entire fec region at 97.3 minutes on the Escherichia coli K-12 chromosome.
Veitinger S, Braun V. ( 1592838 )

Sequences
Amino acid
FASTA format
0001 MTAIKHPVLL WGLPVAALII IFWLSLFCYS AIPVSGADAT RALLPGHTPT LPEALVQNLR LPRSLVAVLI 
0071 GASLALAGTL LQTLTHNPMA SPSLLGINSG AALAMALTSA LSPTPIAGYS LSFIAACGGG VSWLLVMTAG 
0141 GGFRHTHDRN KLILAGIALS AFCMGLTRIT LLLAEDHAYG IFYWLAGGVS HARWQDVWQL LPVVVTAVPV 
0211 VLLLANQLNL LNLSDSTAHT LGVNLTRLRL VINMLVLLLV GACVSVAGPV AFIGLLVPHL ARFWAGFDQR 
0281 NVLPVSMLLG ATLMLLADVL ARALAFPGDL PAGAVLALIG SPCFVWLVRR RG

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             acagtaacac ctgggcgcgg atgcgcggta 
-070 tttttgctgc agagcgtatt gccgctgaca cggtaaaaat cttccaccat cagccgctta ccgttgtgaa 
0001 atgaccgcga taaaacaccc ggtgctgctg tgggggcttc ccgttgcagc acttattatt attttctggc 
0071 tgagtctgtt ttgctactcg gccattcctg tttccggagc agatgcaacc cgcgccctgc tgcctggaca 
0141 cacgccaacg ctaccagaag cgctggtgca aaaccttcgt ttgccacgaa gcctggtcgc cgttctgatc 
0211 ggcgcaagcc tggcgctcgc gggcacgctg ctgcaaaccc tgacccacaa cccaatggcc tctccttcac 
0281 tgctcggcat taacagcggc gcggcgctgg ctatggcgct taccagcgcg ctgagtccga cgccgattgc 
0351 aggctattct ctgtcattca tcgcggcatg cgggggcggc gtgagctggc tgctggtcat gaccgcagga 
0421 ggcggatttc gtcataccca tgacagaaac aaactgatcc tcgcgggtat cgcgctgtcg gccttttgta 
0491 tgggccttac ccgcatcacc ctgctgctgg ccgaagatca tgcttacggc atcttttact ggctggcagg 
0561 cggagtgtcc cacgcccgct ggcaggatgt ctggcagctc ttgccggtgg tggtcactgc agtccctgtc 
0631 gtgttgctgc tggcgaatca actgaacctg ctcaacctca gcgacagcac cgcccatacg ctgggagtga 
0701 acctgacgag gctacgtttg gtcatcaata tgttagtgct gcttctggtt ggtgcgtgcg tcagcgtagc 
0771 aggtccggtg gcgtttatcg gtctgctggt gccacatctg gcgcgcttct gggcaggctt cgatcagcgc 
0841 aacgtactgc cagtgagcat gctgctgggg gccacgctga tgctgctggc agatgtactc gcacgcgcgc 
0911 tggccttccc cggagatctg cccgcaggcg cagtgctggc gctgattggc agcccttgct ttgtctggct 
0981 tgtgaggagg cgaggatgaa aattgcgctg gttattttca tcacccttgc cctggcgggc tgtgcgctgt 
1051 tatcactcca tatgggagtg atccccgtgc cgtggcgcgc gctgctgac