MG1655
W3110
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Gene Report : fecD
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 1989;171(5):2626-33.
Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
     Deletion 1 (LD)  ,  OCR20,24-1 (LD 1-1_CRS) (D)  ,  OCR20,24-2 (LD 1-1_P/O) (D)  ,  OCR21 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fecD
Related strains
     Strains Search Search strains by gene name:  fecD   Search strains by all related name:  fecD b4288 ECK4278 JW4248

General information  (Go to Linear View:)
 Gene Name fecD  
 Alternative name b4288,ECK4278,JW4248  
 Location, Length 4,509,481 - 4,510,437 (  -  ) ;   97.19 min ; 957 (bp) ,   318 (aa) Go to Linear View
 Product KpLE2 phage-like element; iron-dicitrate transporter subunit  
 Operon Name fecABCDE  
 Note citrate-dependent iron transport, membrane-bound protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0005215 ; transporter activity ( fecD )
GO:0005506 ; iron ion binding ( fecD )
GO:0005886 ; plasma membrane ( fecD )
GO:0006810 ; transport ( fecD )
GO:0006811 ; ion transport ( fecD )
GO:0006826 ; iron ion transport ( fecD )
GO:0016020 ; membrane ( fecD )
GO:0016021 ; integral to membrane ( fecD )
 PID 1790740  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) FECD_ECOLI ( P15029 )
    -  Protein name Iron(III) dicitrate transport system permease protein fecD.  
    -  Synonyms  
    -  Gene name Name=fecD; OrderedLocusNames=b4288;  

 Linear View (Whole Mode)
View Location
   4500.0  –  4525.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fecD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, An Inward-Facing Conformation Of A Putative Metal-Chelate Type Abc Transporter.  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Iron  
         PSI-BLAST Iron
    nr     (database updated : 2007.02.20 )
         BLAST KpLE2 phage-like element; iron-dicitrate transporter subunit [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CK2_PHOSPHO_SITE    MYRISTYL    PROKAR_LIPOPROTEIN     

Other Cross-Reference
    COG COG0609P 
    EcoCyc fecD 

MMBR References
J Bacteriol. 1988;170(6):2716-24.
Genetics of the iron dicitrate transport system of Escherichia coli.
Pressler U, Staudenmaier H, Zimmermann L, Braun V. ( 2836368 )
J Bacteriol. 1989;171(5):2626-33.
Nucleotide sequences of the fecBCDE genes and locations of the proteins suggest a periplasmic-binding-protein-dependent transport mechanism for iron(III) dicitrate in Escherichia coli.
Staudenmaier H, Van Hove B, Yaraghi Z, Braun V. ( 2651410 )
J Bacteriol. 1990;172(12):6749-58.
Novel two-component transmembrane transcription control: regulation of iron dicitrate transport in Escherichia coli K-12.
Van Hove B, Staudenmaier H, Braun V. ( 2254251 )
J Bacteriol. 1992;174(11):3838-9.
Localization of the entire fec region at 97.3 minutes on the Escherichia coli K-12 chromosome.
Veitinger S, Braun V. ( 1592838 )

Sequences
Amino acid
FASTA format
0001 MKIALVIFIT LALAGCALLS LHMGVIPVPW RALLTDWQAG HEHYYVLMEY RLPRLLLALF VGAALAVAGV 
0071 LIQGIVRNPL ASPDILGVNH AASLASVGAL LLMPSLPVMV LPLLAFAGGM AGLILLKMLA KTHQPMKLAL 
0141 TGVALSACWA SLTDYLMLSR PQDVNNALLW LTGSLWGRDW SFVKIAIPLM ILFLPLSLSF CRDLDLLALG 
0211 DARATTLGVS VPHTRFWALL LAVAMTSTGV AACGPISFIG LVVPHMMRSI TGGRHRRLLP VSALTGALLL 
0281 VVADLLARII HPPLELPVGV LTAIIGAPWF VWLLVRMR

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             tactcgcacg cgcgctggcc ttccccggag 
-070 atctgcccgc aggcgcagtg ctggcgctga ttggcagccc ttgctttgtc tggcttgtga ggaggcgagg 
0001 atgaaaattg cgctggttat tttcatcacc cttgccctgg cgggctgtgc gctgttatca ctccatatgg 
0071 gagtgatccc cgtgccgtgg cgcgcgctgc tgaccgactg gcaggccgga cacgagcatt attatgtatt 
0141 gatggagtac cgactgccgc gcttgctgct ggcactgttt gtcggtgcag ccctcgccgt ggcgggcgtg 
0211 ctgatacagg ggattgtgcg caaccctctg gcatcaccgg atattctcgg tgttaaccat gccgccagcc 
0281 tggcctctgt gggggctcta cttcttatgc cgtcactgcc cgtgatggtg ctgccgctgc tggcctttgc 
0351 gggcggcatg gcggggttga tattgctgaa gatgctggca aagacccacc agccgatgaa gctggcgctc 
0421 accggcgtgg cgctttctgc atgctgggcc agcctgacgg attatctgat gctctcgcgc ccgcaggatg 
0491 tgaacaacgc cctgctgtgg ctgaccggca gcttatgggg ccgtgactgg agctttgtga agattgccat 
0561 cccgctgatg attttatttc tgccgctgag cctgagtttt tgccgcgatc tcgacctcct tgcactcggc 
0631 gatgcgcgcg ccaccacgct cggtgtgtcg gtgccccata cccgattctg ggctttgtta ctagctgtcg 
0701 ccatgacatc taccggcgtg gccgcctgcg gcccgattag ctttattggt ctcgtggtgc cgcatatgat 
0771 gcgtagcatc accggtggac gtcaccgcag actgctgcct gtttcggccc tgacaggtgc gttgctgttg 
0841 gtggttgccg atctgctggc gagaattatt catcccccac tggagctccc ggttggcgtg ctgaccgcca 
0911 ttatcggtgc gccgtggttt gtctggttgc ttgtgagaat gcgataaatg actttacgaa ctgaaaatct 
0981 gacggtcagt tacgggacag acaaggtact taacgacgtt tcactctcac tgccaacggg gaagatcacc 
1051 gccctga