MG1655
W3110
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Gene Report : treB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR19 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  treB
Related strains
     Strains Search Search strains by gene name:  treB   Search strains by all related name:  treB b4240 ECK4235 JW4199

General information  (Go to Linear View:)
 Gene Name treB  
 Alternative name b4240,ECK4235,JW4199  
 Location, Length 4,462,782 - 4,464,203 (  -  ) ;   96.19 min ; 1422 (bp) ,   473 (aa) Go to Linear View
 Product fused trehalose(maltose)-specific PTS enzyme:IIB component/IIC component  
 Operon Name treBC  
 Note PTS system enzyme II, trehalose specific; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006006 - glucose metabolic process  
 Function transport; Transport of small molecules: Carbohydrates, organic acids, alcohols  
 Gene Ontology GO:0005351 ; sugar:hydrogen ion symporter activity ( treB )
GO:0005886 ; plasma membrane ( treB )
GO:0006810 ; transport ( treB )
GO:0008643 ; carbohydrate transport ( treB )
GO:0008982 ; protein-N(PI)-phosphohistidine-sugar phosphotransferase activity ( treB )
GO:0009276 ; 1-2nm peptidoglycan-based cell wall ( treB )
GO:0009401 ; phosphoenolpyruvate-dependent sugar phosphotransferase system ( treB )
GO:0015574 ; trehalose transmembrane transporter activity ( treB )
GO:0015771 ; trehalose transport ( treB )
GO:0016020 ; membrane ( treB )
GO:0016021 ; integral to membrane ( treB )
GO:0016740 ; transferase activity ( treB )
 PID 2367362  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) PTTB_ECOLI ( P36672 )
    -  Protein name PTS system, trehalose-specific IIBC component  
    -  Synonyms EIIBC-Tre, Trehalose- permease IIBC component, Phosphotransferase enzyme II, BC component, EC 2.7.1.69, EII-Tre  
    -  Gene name Name=treB; OrderedLocusNames=b4240;  

 Linear View (Whole Mode)
View Location
   4450.0  –  4475.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP treB (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Ph0066 From Pyrococcus Horikoshii  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST PTS system trehalose-specific EIIBC component  
         PSI-BLAST PTS system sucrose-specific EIIBC component
    nr     (database updated : 2007.02.20 )
         BLAST fused trehalose(maltose)-specific PTS enzyme: IIB component/IIC component [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    MULTICOPPER_OXIDASE1    PTS_EIIB_CYS     

Other Cross-Reference
    COG COG1263G 
    EcoCyc treB 

MMBR References
Mol Microbiol. 1993;8(2):205-10.
Trehalose metabolism in Escherichia coli: stress protection and stress regulation of gene expression.
Strom AR, Kaasen I. ( 8391102 )
J Bacteriol. 1990;172(6):3450-61.
Trehalose transport and metabolism in Escherichia coli.
Boos W, Ehmann U, Forkl H, Klein W, Rimmele M, Postma PW. ( 2160944 )

Sequences
Amino acid
FASTA format 
0001 MMSKINQTDI DRLIELVGGR GNIATVSHCI TRLRFVLNQP ANARPKEIEQ LPMVKGCFTN AGQFQVVIGT 
0071 NVGDYYQALI ASTGQAQVDK EQVKKAARHN MKWHEQLISH FAVIFFPLLP ALISGGLILG FRNVIGDLPM 
0141 SNGQTLAQMY PSLQTIYDFL WLIGEAIFFY LPVGICWSAV KKMGGTPILG IVLGVTLVSP QLMNAYLLGQ 
0211 QLPEVWDFGM FSIAKVGYQA QVIPALLAGL ALGVIETRLK RIVPDYLYLV VVPVCSLILA VFLAHALIGP 
0281 FGRMIGDGVA FAVRHLMTGS FAPIGAALFG FLYAPLVITG VHQTTLAIDL QMIQSMGGTP VWPLIALSNI 
0351 AQGSAVIGII ISSRKHNERE ISVPAAISAW LGVTEPAMYG INLKYRFPML CAMIGSGLAG LLCGLNGVMA 
0421 NGIGVGGLPG ILSIQPSYWQ VFALAMAIAI IIPIVLTSFI YQRKYRLGTL DIV
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             attgtgatct tcgctgcgtt tcgggaacgt 
-070 tcccgttttt aaatttttcc gcgcaatata ttctgcagcc aaccaaaaat gtcatctgcc atggggcttt 
0001 atgatgagca aaataaacca aacggatatc gatcggttga ttgaactggt cggcgggcgc ggcaatattg 
0071 cgacggtgag ccactgtatt actcgcctac gctttgtcct caaccaaccg gccaatgcca gaccgaaaga 
0141 aattgagcaa ctccctatgg tgaaaggctg tttcaccaat gccgggcaat ttcaggtggt gattggcacc 
0211 aacgtgggtg attactatca agcactgatt gcgtcaaccg gacaggcgca ggttgataaa gagcaggtaa 
0281 aaaaagccgc ccggcataat atgaaatggc atgagcagtt gatctctcat ttcgcggtga tcttcttccc 
0351 gttgctgccc gcgttgatta gcggcggttt gatcctcggt tttcgcaatg tgatcggcga tttgcccatg 
0421 agcaacggtc agacgctggc gcaaatgtac ccttccctgc aaacgatcta cgattttctg tggttgatcg 
0491 gtgaagcgat cttcttctac ctgccggtcg gtatttgctg gtcagcggtg aaaaaaatgg gcggcacgcc 
0561 gatccttggt atcgtgcttg gcgtgacact ggtttctcca cagctgatga acgcttatct gctcgggcag 
0631 cagctgccgg aagtgtggga ctttggcatg ttcagcatcg ccaaagtagg ctatcaggcg caggtgatcc 
0701 cggcactgtt agccggactg gcgctgggcg ttattgaaac tcgccttaaa cgcatcgtgc cggattacct 
0771 ctatctggtg gtggtacccg tctgttcgct gatcctcgcg gtgttcctcg cccatgcgct gattggtccg 
0841 tttggtcgca tgattggcga tggcgttgcc tttgcggtac gtcacctgat gaccggcagc tttgctccga 
0911 ttggcgcagc attgtttggc ttcctgtacg ccccgctggt gatcaccggt gtacaccaga ccacgcttgc 
0981 tattgatttg cagatgattc aaagcatggg tggtacgcca gtgtggccgc tgattgcgct gtcgaatatc 
1051 gctcagggct ccgccgtgat aggcattatc atttccagcc gcaagcacaa tgaacgcgag atctccgtgc 
1121 ctgccgctat ctccgcctgg cttggggtca ctgagcctgc aatgtacggc atcaacctga aatatcgctt 
1191 cccgatgctg tgcgcgatga ttggttctgg tctggcagga ttgctatgcg gcctgaacgg cgttatggcg 
1261 aatggcatcg gcgtaggcgg cctgccggga attctctcga ttcaaccgag ctactggcag gtgtttgcgc 
1331 tggcaatggc tatcgccatc atcatcccga ttgtactcac ctcgtttatc tatcagcgga aataccgcct 
1401 gggcacgctg gacattgttt aattttcttc ggggcgcaat tgcgccccct cgcattcgca ggaataacgt 
1471 aatgactcat cttccccact ggtggcaaaa cggcgttatc taccagattt at