|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Microbiol Mol Biol Rev. 1998;62(3):814-984
Linkage map of Escherichia coli K-12, edition 10: the traditional map.
Berlyn MK.
(
9729611
)
|
|
|
Deletion
|
4
(LD)
,
OCR13,15-3 (LD 4E_CRS)
(D)
,
OCR13,15-4 (LD 4E_P/O)
(D)
,
OCR14
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
phnC
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
phnC
Search strains by all related name:
phnC b4106 ECK4099 f262 JW4067
|
General information (Go to Linear View: )
|
|
Gene Name
|
phnC
|
|
Alternative name
|
b4106,ECK4099,f262,JW4067
|
|
Location, Length
|
4,322,400 - 4,323,188
(
-
)
;
93.16
min
;
789
(bp) ,
262
(aa)
|
|
Product
|
phosphonate ABC transporter ATP-binding subunit
|
|
Operon Name
|
phnCDEEFGHIJKLMNOP
|
|
Note
|
ATP-binding component of phosphonate transport; ATP-binding component of ABC superfamily; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006793 - phosphorus metabolic process
|
|
Function
|
transport; Central intermediary metabolism: Phosphorus compounds
|
|
Gene Ontology
|
GO:0000166
;
nucleotide binding ( phnC )
GO:0005515
;
protein binding ( phnC )
GO:0005524
;
ATP binding ( phnC )
GO:0005886
;
plasma membrane ( phnC )
GO:0006810
;
transport ( phnC )
GO:0015416
;
phosphonate transmembrane-transporting ATPase activity ( phnC )
GO:0015716
;
phosphonate transport ( phnC )
GO:0016020
;
membrane ( phnC )
GO:0016787
;
hydrolase activity ( phnC )
GO:0016887
;
ATPase activity ( phnC )
GO:0017111
;
nucleoside-triphosphatase activity ( phnC )
|
|
PID
|
1790544
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
PHNC_ECOLI
(
P16677
)
|
|
- Protein name
|
Phosphonates transport ATP-binding protein phnC.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=phnC; OrderedLocusNames=b4106;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
phnC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain 1, Malk
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Phosphonates import ATP-binding protein phnC
|
|
PSI-BLAST
|
Phosphate import ATP-binding protein pstB
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
phosphonate/organophosphate ester transporter subunit [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ATP_GTP_A
ABC_TRANSPORTER
|
|
MMBR References
|
J Bacteriol. 1991;173(8):2665-72.
Molecular analysis of the cryptic and functional phn operons for phosphonate use in Escherichia coli K-12.
Makino K, Kim SK, Shinagawa H, Amemura M, Nakata A.
(
1840580
)
|
J Bacteriol. 1991;173(2):587-600.
Involvement of the Escherichia coli phn (psiD) gene cluster in assimilation of phosphorus in the form of phosphonates, phosphite, Pi esters, and Pi.
Metcalf WW, Wanner BL.
(
1846145
)
|
J Bacteriol. 1993;175:3430-3442
Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements.
Metcalf, W. W., and B. L. Wanner.
|
FEMS Microbiol Lett. 1992;79(1-3):133-9.
Molecular genetic studies of a 10.9-kb operon in Escherichia coli for phosphonate uptake and biodegradation.
Wanner BL, Metcalf WW.
(
1335942
)
|
J Biol Chem. 1990;265:4461-4471
Molecular biology of carbon-phosphorus bond cleavage. Cloning and sequencing of the phn (psiD) genes involved in alkylphosphonate uptake and C-P lyase activity in Escherichia coli B.
Chen, C. M., Q. Z. Ye, Z. M. Zhu, B. L. Wanner, and C. T. Walsh.
|
| Sequences |
Amino acid
FASTA format
|
0001 MQTIIRVEKL AKTFNQHQAL HAVDLNIHHG EMVALLGPSG SGKSTLLRHL SGLITGDKSV GSHIELLGRT
0071 VQREGRLARD IRKSRAHTGY IFQQFNLVNR LSVLENVLIG ALGSTPFWRT CFSWFTGEQK QRALQALTRV
0141 GMVHFAHQRV STLSGGQQQR VAIARALMQQ AKVILADEPI ASLDPESARI VMDTLRDINQ NDGITVVVTL
0211 HQVDYALRYC ERIVALRQGH VFYDGSSQQF DNERFDHLYR SINRVEENAK AA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tcgaattccc gttaactctt catctgttag
-070 tcacttttaa ttaaccaaat cgtcacaata atccgccacg atggagccac ttttttaggg aggctgcatc
0001 atgcaaacga ttatccgtgt cgagaagctc gccaaaacct tcaatcagca tcaggcgctg catgcggttg
0071 atctgaacat tcatcacggt gaaatggtgg ctctgcttgg gccgtcgggt tccggaaaat ccaccctttt
0141 acgtcactta agcggtttga ttaccggcga taaatctgtc ggtagccata tcgagctgct gggccgcaca
0211 gtccagcgcg aaggccgcct ggcccgcgat atccgcaaaa gccgcgccca taccggctac atattccaac
0281 aattcaacct ggtgaaccgc ctgagcgtac tggagaacgt gctgattggc gcgctcggca gcacgccgtt
0351 ctggcgcacc tgttttagct ggttcaccgg cgagcagaaa cagcgcgcgt tacaggcgct gacccgcgtt
0421 ggcatggtgc attttgccca tcagcgcgtt tccaccctct ccggcggcca gcagcaacgt gtggcgattg
0491 cccgtgcgct gatgcagcag gcgaaagtga ttctggccga tgaacccatc gcctcgctgg acccagaatc
0561 agcgcgcatc gtgatggaca ccctgcgcga catcaaccag aacgacggca tcaccgtggt cgtcacgctg
0631 catcaggtgg attacgccct gcgctactgc gaacgcatcg tcgccctgcg ccaggggcac gtcttctacg
0701 acggcagcag ccaacagttt gataacgaac gttttgacca tctctaccgc agcattaacc gcgtcgaaga
0771 gaacgcgaaa gctgcctgac atccccatca ttgaggaaaa cgaatgaacg ctaagataat tgcctcgctg
0841 gccttcacca gcatgttcag cctcagcacc ctgttaagcc cggcgcacg
|
