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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCL02
(D)
,
DE(OC3)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
bglF
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Related strains
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Strains Search
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Search strains by gene name:
bglF
Search strains by all related name:
bglF b3722 bglC bglS ECK3715 f625 JW3700
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General information (Go to Linear View: )
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Gene Name
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bglF
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Alternative name
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b3722,bglC,bglS,ECK3715,f625,JW3700
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Location, Length
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3,901,743 - 3,903,620
(
-
)
;
84.10
min
;
1878
(bp) ,
625
(aa)
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Product
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fused beta-glucoside-specific PTS enzymes: IIAcomponent/IIB component/IIC component
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Operon Name
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bglGFB
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Note
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PTS system beta-glucosides, enzyme II, cryptic; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0016052 - carbohydrate catabolic process; GO_process: GO:0006464 - protein modification process
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Function
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enzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols
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Gene Ontology
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GO:0005351
;
sugar:hydrogen ion symporter activity ( bglF )
GO:0005886
;
plasma membrane ( bglF )
GO:0006810
;
transport ( bglF )
GO:0008643
;
carbohydrate transport ( bglF )
GO:0008982
;
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity ( bglF )
GO:0009401
;
phosphoenolpyruvate-dependent sugar phosphotransferase system ( bglF )
GO:0016020
;
membrane ( bglF )
GO:0016021
;
integral to membrane ( bglF )
GO:0016740
;
transferase activity ( bglF )
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PID
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1790159
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EC number
(KEGG Pathway)
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2.7.1.69
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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PTBA_ECOLI
(
P08722
)
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- Protein name
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PTS system, beta-glucoside-specific IIABC component
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- Synonyms
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EIIABC-Bgl, Beta-glucoside-permease IIABC component, Phosphotransferase enzyme II, ABC component, EC 2.7.1.69, EII-Bgl
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- Gene name
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Name=bglF; Synonyms=bglC, bglS; OrderedLocusNames=b3722;
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MMBR References
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J Bacteriol. 1987;169(6):2570-8.
Positive and negative regulation of the bgl operon in Escherichia coli.
Mahadevan S, Reynolds AE, Wright A.
(
3294798
)
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Proc Natl Acad Sci U S A. 1990;87:5074-5078
Beta-glucoside permease represses the bgl operon of Escherichia coli by phosphorylation of the antiterminator protein and also interacts with glucose-specific enzyme III, the key element in catabolite control.
Schnetz, K., and B. Rak.
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J Gen Microbiol. 1987;133(3):563-73.
Nucleotide sequence of bglC, the gene specifying enzymeIIbgl of the PEP:sugar phosphotransferase system in Escherichia coli K12, and overexpression of the gene product.
Bramley HF, Kornberg HL.
(
3309161
)
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EMBO J. 1997;16:4617-4627
BglF, the sensor of the E. coli bgl system, uses the same site to phosphorylate both a sugar and a regulatory protein.
Chen, Q., J. C. Arents, R. Bader, P. W. Postma, and O. Amster-Choder.
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| Sequences |
Amino acid
FASTA format
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0001 MTELARKIVA GVGGADNIVS LMHCATRLRF KLKDESKAQA EVLKKTPGII MVVESGGQFQ VVIGNHVADV
0071 FLAVNSVAGL DEKAQQAPEN DDKGNLLNRF VYVISGIFTP LIGLMAATGI LKGMLALALT FQWTTEQSGT
0141 YLILFSASDA LFWFFPIILG YTAGKRFGGN PFTAMVIGGA LVHPLILTAF ENGQKADALG LDFLGIPVTL
0211 LNYSSSVIPI IFSAWLCSIL ERRLNAWLPS AIKNFFTPLL CLMVITPVTF LLVGPLSTWI SELIAAGYLW
0281 LYQAVPAFAG AVMGGFWQIF VMFGLHWGLV PLCINNFTVL GYDTMIPLLM PAIMAQVGAA LGVFLCERDA
0351 QKKVVAGSAA LTSLFGITEP AVYGVNLPRK YPFVIACISG ALGATIIGYA QTKVYSFGLP SIFTFMQTIP
0421 STGIDFTVWA SVIGGVIAIG CAFVGTVMLH FITAKRQPAQ GAPQEKTPEV ITPPEQGGIC SPMTGEIVPL
0491 IHVADTTFAS GLLGKGIAIL PSVGEVRSPV AGRIASLFAT LHAIGIESDD GVEILIHVGI DTVKLDGKFF
0561 SAHVNVGDKV NTGDRLISFD IPAIREAGFD LTTPVLISNS DDFTDVLPHG TAQISAGEPL LSIIR
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 ctaagcgggc aaaacctgaa aaaaattgct
-070 tgattcacgt caggccgttt ttttcaggtt tttttttgga gttttgccgc aaagcggtag agggcaagtt
0001 atgacggagt tagccagaaa aatagtcgca ggagtcgggg gcgcagataa cattgtgagt ctgatgcatt
0071 gcgcaacgcg attacgtttt aaattaaagg atgaaagcaa agcgcaagca gaggtactga aaaagacccc
0141 cggtattatt atggtggtgg aaagcggtgg ccagtttcag gtggtcatag gtaaccatgt ggccgatgtc
0211 ttcctggcgg ttaacagtgt ggcaggcctt gacgaaaaag cgcaacaggc accggaaaat gatgataaag
0281 gtaatctgct aaaccgcttt gtttatgtta tttcaggtat ttttacgcct ctgatcggtt tgatggcggc
0351 aaccgggatc ttgaaaggta tgctggctct ggcgctcact tttcagtgga cgaccgaaca aagtggtact
0421 tatttaattt tattcagcgc cagtgatgcc ttgttttggt tcttcccgat aatcctggga tacaccgcgg
0491 ggaaacgctt cggcggtaat ccatttactg ccatggtgat tggtggagcg ttagtgcatc cattaattct
0561 gactgctttc gagaacgggc aaaaagcgga tgcgctgggg ctggatttcc tgggtattcc ggtcacattg
0631 ttgaattact cgtcatcggt tattcccatt attttttctg cctggttgtg cagcattctg gaacgccgac
0701 ttaatgcgtg gttaccgtcg gcaatcaaaa atttcttcac accattgcta tgtctgatgg ttatcacacc
0771 cgtcaccttt ctgctggtgg ggccgctatc aacctggata agcgaactga ttgccgccgg ttatctctgg
0841 ctttatcagg cggttcctgc atttgcgggc gcggtaatgg gcggcttctg gcaaatcttc gtcatgttcg
0911 gactgcactg gggcctggtg ccgctgtgta tcaataactt caccgtgctg ggctacgaca ccatgatccc
0981 gctgttaatg cccgccatta tggcgcaggt cggggcggcg ctcggcgtct tcctctgcga acgcgatgcg
1051 cagaaaaaag tggtggcggg atcagcggcg ttgacgagtc tgtttggtat caccgaacca gcggtatatg
1121 gcgtcaacct gccgcgtaag tacccctttg ttatcgcctg tatcagtggg gctttggggg ccaccattat
1191 tggctacgcg caaacgaaag tctactcctt tggtttgcca agtattttca ccttcatgca aaccatcccg
1261 tcaacgggaa ttgatttcac cgtctgggcc agcgttattg gcggtgtcat tgccatcggt tgcgcatttg
1331 tcggtacggt gatgcttcat ttcatcaccg ctaaacgtca gccagcgcag ggtgccccgc aagagaaaac
1401 accagaggtt attacaccac ctgagcaggg cggtatctgt tcaccgatga cgggagagat tgtgccgctc
1471 attcacgtcg ctgataccac gtttgccagt ggcctgttgg gtaaaggtat tgccattctg ccctcggttg
1541 gtgaagtgcg ttctccggtt gcgggtcgaa ttgcttcgtt gttcgccaca ttacacgcca ttggcattga
1611 gtcagatgat ggtgtggaga tcctgattca tgtcggtatc gacaccgtaa aactggacgg caaattcttt
1681 tccgctcacg tcaacgtggg tgacaaggtc aatacaggcg atcggctgat ttcttttgat atccctgcta
1751 ttcgcgaggc cggatttgat ctgacgacgc cggtattaat cagtaatagc gatgatttta cggacgtatt
1821 accccacggc acggcgcaga taagcgcagg tgaaccgctg ttatccatca ttcgctaacg ataaaaggag
1891 ttaattatga aagcatttcc agaaacattt ctttggggtg gcgcaacagc tgccaatcag gtggaaggtg
1961 cctggcagga agatggca
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