MG1655
W3110
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Gene Report : nikD
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL17 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  nikD
Related strains
     Strains Search Search strains by gene name:  nikD   Search strains by all related name:  nikD b3479 ECK3463 hydC hydD JW3444 o254

General information  (Go to Linear View:)
 Gene Name nikD  
 Alternative name b3479,ECK3463,hydC,hydD,JW3444,o254  
 Location, Length 3,615,038 - 3,615,802 (  +  ) ;   77.92 min ; 765 (bp) ,   254 (aa) Go to Linear View
 Product nickel transporter subunit  
 Operon Name nikABCDER  
 Note ATP-binding protein of nickel transport system; ATP-binding component of ABC superfamily; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009060 - aerobic respiration; GO_process: GO:0009061 - anaerobic respiration  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0000166 ; nucleotide binding ( nikD )
GO:0005524 ; ATP binding ( nikD )
GO:0005886 ; plasma membrane ( nikD )
GO:0006810 ; transport ( nikD )
GO:0015413 ; nickel-transporting ATPase activity ( nikD )
GO:0015675 ; nickel ion transport ( nikD )
GO:0016020 ; membrane ( nikD )
GO:0016151 ; nickel ion binding ( nikD )
GO:0016787 ; hydrolase activity ( nikD )
GO:0016887 ; ATPase activity ( nikD )
GO:0017111 ; nucleoside-triphosphatase activity ( nikD )
 PID 1789890  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) NIKD_ECOLI ( P33593 )
    -  Protein name Nickel transport ATP-binding protein nikD.  
    -  Synonyms  
    -  Gene name Name=nikD; OrderedLocusNames=b3479;  

 Linear View (Whole Mode)
View Location
   3605.0  –  3630.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP nikD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The Atpase Subunit Cysa Of The Putative Sulfate Atp-Binding Cassette (Abc) Transporter From Alicyclobacillus Acidocaldarius  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Nickel import ATP-binding protein nikD  
         PSI-BLAST Phosphate import ATP-binding protein pstB
    nr     (database updated : 2007.02.20 )
         BLAST nickel transporter subunit [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE GLYCOSAMINOGLYCAN    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    ABC_TRANSPORTER     

Other Cross-Reference
    COG COG0444EP 
    EcoCyc nikD 

MMBR References
Mol Microbiol. 1993;9(6):1181-91.
The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.
Navarro C, Wu LF, Mandrand-Berthelot MA. ( 7934931 )
Gene. 1991;107(1):37-42.
The hydC region contains a multi-cistronic operon (nik) involved in nickel transport in Escherichia coli.
Wu LF, Navarro C, Mandrand-Berthelot MA. ( 1743519 )

Sequences
Amino acid
FASTA format
0001 MPQQIELRNI ALQAAQPLVH GVSLTLQRGR VLALVGGSGS GKSLTCAATL GILPAGVRQT AGEILADGKP 
0071 VSPCALRGIK IATIMQNPRS AFNPLHTMHT HARETCLALG KPADDATLTA AIEAVGLENA ARVLKLYPFE 
0141 MSGGMLQRMM IAMAVLCESP FIIADEPTTD LDVVAQARIL DLLESIMQKQ APGMLLVTHD MGVVARLADD 
0211 VAVMSDGKIV EQGDVETLFN APKHTVTRSL VSAHLALYGM ELAS

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             CGGGGCTGGC GCTGTTTATC AGCGTGATGG 
-070 CCTTTAACCT GGTGGGTGAC GCACTGCGCG ATCATCTGGA CCCTCATCTG GTGACGGAGC ACGCACACTA 
0001 atgccgcaac agattgaact acgtaatatc gcgctacagg ccgcgcagcc gctggtacac ggtgtatcgt 
0071 taaccctgca acgcgggcgc gtgctggcgt tagtcggcgg tagcggcagc gggaaatcat taacctgcgc 
0141 cgcaacgctg ggcattttgc ccgctggcgt tcgccagacg gcgggggaaa ttttagccga tggcaaaccg 
0211 gtttcgcctt gcgccctgcg cggcatcaaa attgccacca tcatgcagaa cccgcgcagc gcctttaatc 
0281 cactgcacac catgcacacc cacgcgcggg aaacctgcct ggcgttaggg aaacccgccg atgacgctac 
0351 gcttaccgct gccatagaag cggtggggct ggaaaacgcc gcgcgcgtgc tgaagctgta cccgttcgag 
0421 atgagcggcg gcatgttgca gcgcatgatg attgcgatgg cggtgctgtg tgaatcaccg tttatcatcg 
0491 ccgatgaacc gaccaccgac cttgacgtgg tagcacaggc gcgcatcctc gatctgctgg aaagcattat 
0561 gcaaaaacaa gcgccgggaa tgctgctggt gacccatgat atgggcgttg tggcgcgtct ggcggatgac 
0631 gtggcggtga tgtctgacgg taagattgtc gaacagggcg atgtagaaac gctgtttaac gcccccaaac 
0701 atacagtgac gcgcagcctg gtttccgctc atctcgccct ctacggtatg gagctggcat catgaCTTTA 
0771 CTTAACATCT CCGGCCTTTC CCATCACTAT GCGCACGGTG GATTTAACGG AAAACATCAA CATCAGGCGG 
0841 TGCTGAATAA CGTTTCCCTG ACCCT