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PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCL17
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
nikC
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
nikC
Search strains by all related name:
nikC b3478 ECK3462 hydC hydD JW3443 o277
|
General information (Go to Linear View: )
|
|
Gene Name
|
nikC
|
|
Alternative name
|
b3478,ECK3462,hydC,hydD,JW3443,o277
|
|
Location, Length
|
3,614,205 - 3,615,038
(
+
)
;
77.90
min
;
834
(bp) ,
277
(aa)
|
|
Product
|
nickel transporter subunit
|
|
Operon Name
|
nikABCDER
|
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Note
|
transport of nickel, membrane protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
|
|
Function
|
transport; Transport of small molecules: Cations
|
|
Gene Ontology
|
GO:0005215
;
transporter activity ( nikC )
GO:0005886
;
plasma membrane ( nikC )
GO:0006810
;
transport ( nikC )
GO:0015675
;
nickel ion transport ( nikC )
GO:0016020
;
membrane ( nikC )
GO:0016021
;
integral to membrane ( nikC )
GO:0016151
;
nickel ion binding ( nikC )
|
|
PID
|
1789889
|
EC number
(KEGG Pathway)
|
|
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
NIKC_ECOLI
(
P33592
)
|
|
- Protein name
|
Nickel transport system permease protein nikC.
|
|
- Synonyms
|
|
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- Gene name
|
Name=nikC; OrderedLocusNames=b3478, z4870, ECs4345;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
nikC
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Structural Basis Of The Multiple Binding Capacity Of The Acrb Multidrug Efflux Pump
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Nickel transport system permease protein nikC
|
|
PSI-BLAST
|
Dipeptide transport system permease protein dppC
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
transport of nickel, membrane protein [Escherichia coli O157:H7 EDL933]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
MYRISTYL
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|
MMBR References
|
Mol Microbiol. 1993;9(6):1181-91.
The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.
Navarro C, Wu LF, Mandrand-Berthelot MA.
(
7934931
)
|
Gene. 1991;107(1):37-42.
The hydC region contains a multi-cistronic operon (nik) involved in nickel transport in Escherichia coli.
Wu LF, Navarro C, Mandrand-Berthelot MA.
(
1743519
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MNFFLSSRWS VRLALIIIAL LALIALTSQW WLPYDPQAID LPSRLLSPDA QHWLGTDHLG RDIFSRLMAA
0071 TRVSLGSVMA CLLLVLTLGL VIGGSAGLIG GRVDQATMRV ADMFMTFPTS ILSFFMVGVL GTGLTNVIIA
0141 IALSHWAWYA RMVRSLVISL RQREFVLASR LSGAGHVRVF VDHLAGAVIP SLLVLATLDI GHMMLHVAGM
0211 SFLGLGVTAP TAEWGVMIND ARQYIWTQPL QMFWPGLALF ISVMAFNLVG DALRDHLDPH LVTEHAH
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGCTGATGAT GGTGGTGGTT TTTGTGGTCT
-070 GTAATTTGAT TGTCGATTTG CTCAACGCCG CGCTGGACCC GCGCATTCGT CGTCATGAAG GAGCGCACGC
0001 gtgaactttt tcctctcttc ccgctggtcg gtacgcctgg cgctgatcat tatcgccctg ctggcgctga
0071 ttgcgctcac cagccagtgg tggctgccgt atgacccaca ggcgattgat ttgccgtcgc gcctgctttc
0141 gccggatgcg cagcactggc tgggcaccga tcacttaggt cgcgatattt tctcgcggct gatggcagcg
0211 acccgcgtgt cgctcggttc ggtaatggcc tgcctgctgc tggtgctgac attagggctg gttattggcg
0281 gcagcgccgg gttgattggc gggcgcgttg atcaggccac catgcgcgtc gccgatatgt ttatgacctt
0351 cccgacctcg attctgtcgt tctttatggt tggcgtgctc ggcaccgggc tgaccaacgt aattatcgcc
0421 atcgccctgt cgcactgggc gtggtatgca cgcatggtgc gcagcctggt gatttcacta cgccaacgcg
0491 agtttgtgct ggcgtcacgg ctttccggtg cgggccatgt gcgggtgttt gtcgatcatc tggcaggcgc
0561 ggtgatccct tcgctgctgg tgctggcaac gctggatatc ggccatatga tgctgcacgt cgcggggatg
0631 tctttccttg gcctcggtgt gaccgcgccg accgccgaat ggggcgtgat gattaacgac gcgcgccagt
0701 atatctggac ccagccgctg caaatgttct ggccggggct ggcgctgttt atcagcgtga tggcctttaa
0771 cctggtgggt gacgcactgc gcgatcatct ggaccctcat ctggtgacgg agcacgcaca ctaaTGCCGC
0841 AACAGATTGA ACTACGTAAT ATCGCGCTAC AGGCCGCGCA GCCGCTGGTA CACGGTGTAT CGTTAACCCT
0911 GCAACGCGGG CGCGTGCTGG CGTT
|
