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PEC Original Annotations
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|
Essentiality
|
|
Class
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non-essential
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|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
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Deletion
|
OCL17
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
nikB
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
nikB
Search strains by all related name:
nikB b3477 ECK3461 hydC hydD JW3442 o314
|
General information (Go to Linear View: )
|
|
Gene Name
|
nikB
|
|
Alternative name
|
b3477,ECK3461,hydC,hydD,JW3442,o314
|
|
Location, Length
|
3,613,264 - 3,614,208
(
+
)
;
77.88
min
;
945
(bp) ,
314
(aa)
|
|
Product
|
nickel transporter subunit
|
|
Operon Name
|
nikABCDER
|
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Note
|
transport of nickel, membrane protein; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
|
|
Function
|
transport; Transport of small molecules: Cations
|
|
Gene Ontology
|
GO:0005215
;
transporter activity ( nikB )
GO:0005886
;
plasma membrane ( nikB )
GO:0006810
;
transport ( nikB )
GO:0015675
;
nickel ion transport ( nikB )
GO:0016020
;
membrane ( nikB )
GO:0016021
;
integral to membrane ( nikB )
GO:0016151
;
nickel ion binding ( nikB )
|
|
PID
|
1789888
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
NIKB_ECOLI
(
P33591
)
|
|
- Protein name
|
Nickel transport system permease protein nikB.
|
|
- Synonyms
|
|
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- Gene name
|
Name=nikB; OrderedLocusNames=b3477;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
nikB
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Nickel transport system permease protein nikB
|
|
PSI-BLAST
|
Nickel transport system permease protein nikB
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
nickel transporter subunit [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
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PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
MICROBODIES_CTER
|
|
MMBR References
|
Mol Microbiol. 1993;9(6):1181-91.
The nik operon of Escherichia coli encodes a periplasmic binding-protein-dependent transport system for nickel.
Navarro C, Wu LF, Mandrand-Berthelot MA.
(
7934931
)
|
Gene. 1991;107(1):37-42.
The hydC region contains a multi-cistronic operon (nik) involved in nickel transport in Escherichia coli.
Wu LF, Navarro C, Mandrand-Berthelot MA.
(
1743519
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MLRYVLRRFL LLIPMVLAAS VIIFLMLRLG TGDPALDYLR LSNLPPTPEM LASTRTMLGL DQPLYVQYGT
0071 WLWKALHLDF GISFASQRPV LDDMLNFLPA TLELAGAALV LILLTSVPLG IWAARHRDRL PDFAVRFIAF
0141 LGVSMPNFWL AFLLVMAFSV YLQWLPAMGY GGWQHIILPA VSIAFMSLAI NARLLRASML DVAGQRHVTW
0211 ARLRGLNDKQ TERRHILRNA SLPMITAVGM HIGELIGGTM IIENIFAWPG VGRYAVSAIF NRDYPVIQCF
0281 TLMMVVVFVV CNLIVDLLNA ALDPRIRRHE GAHA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TCTCAATGAT GGTGGTATCA AAACCGGAGC
-070 TGGGTAACAT CCCCTACGCG CCGATCGCCA CCGAAATTCC GTTCGAACAG ATTAAACCGG TGAAACCTTA
0001 atgttgcgtt acgtattacg ccgctttctg ctgctgatcc cgatggtgct cgccgcctcg gtgatcattt
0071 ttctgatgct gcgcctcggt accggcgacc cggcgctcga ttatttgcgt ctgtctaacc tgccgccgac
0141 gccggagatg ctggcctcta cccgcaccat gctgggactg gatcagccgc tgtacgtcca gtacggcacc
0211 tggttgtgga aggcgctgca tcttgacttt ggtatctcat tcgccagcca acgcccggta ctggacgata
0281 tgctgaactt cctgcccgcc acgctggaac ttgcaggtgc ggcgctggta ttaattctgc tcacttccgt
0351 accgctcggt atctgggcgg cgcgccatcg cgaccgtctg ccggatttcg ccgtacgttt catcgcgttt
0421 cttggcgtgt cgatgcctaa cttctggctg gcgtttttac tggtgatggc gttttcggtg tatctgcaat
0491 ggctacccgc gatgggttac ggcggctggc agcacatcat tttgcctgcg gtttccattg cctttatgtc
0561 gctggcgatt aacgcgcgtt tactgcgcgc cagtatgctg gacgtcgccg gtcagcgtca cgtcacctgg
0631 gcgcgtctgc gcggcctgaa cgacaaacag accgaacgtc gccacatcct gcgcaatgcc tcgctgccga
0701 tgatcaccgc cgtggggatg catatcggcg aactgattgg cgggacgatg attatcgaaa acatctttgc
0771 ctggccgggc gtcgggcgct atgcggtgtc ggcgattttt aaccgtgact atccggtgat ccagtgcttt
0841 acgctgatga tggtggtggt ttttgtggtc tgtaatttga ttgtcgattt gctcaacgcc gcgctggacc
0911 cgcgcattcg tcgtcatgaa ggagcgcacg cgtgaACTTT TTCCTCTCTT CCCGCTGGTC GGTACGCCTG
0981 GCGCTGATCA TTATCGCCCT GCTGGCGCTG ATTGCGCTCA CCAGCCAGTG GTGGCTGCCG TATGA
|
