MG1655
W3110
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Gene Report : livG
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL18 (D)  ,  OCL18-2 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  livG
Related strains
     Strains Search Search strains by gene name:  livG   Search strains by all related name:  livG b3455 ECK3439 hrbB hrbC hrbD JW3420

General information  (Go to Linear View:)
 Gene Name livG  
 Alternative name b3455,ECK3439,hrbB,hrbC,hrbD,JW3420  
 Location, Length 3,591,462 - 3,592,229 (  -  ) ;   77.41 min ; 768 (bp) ,   255 (aa) Go to Linear View
 Product leucine/isoleucine/valine transporter subunit  
 Operon Name livKHMGF  
 Note ATP-binding component of high-affinity branched-chain amino acid transport system; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009063 - cellular amino acid catabolic process; GO_process: GO:0009098 - leucine biosynthetic process  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0000166 ; nucleotide binding ( livG )
GO:0005524 ; ATP binding ( livG )
GO:0006810 ; transport ( livG )
GO:0006865 ; amino acid transport ( livG )
GO:0016887 ; ATPase activity ( livG )
GO:0017111 ; nucleoside-triphosphatase activity ( livG )
 PID 1789864  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) LIVG_ECOLI ( P22730 )
    -  Protein name High-affinity branched-chain amino acid transport ATP-binding protein livG  
    -  Synonyms LIV-I protein G  
    -  Gene name Name=livG; OrderedLocusNames=b3455, z4825, ECs4302, SF3473, S4290;  

 Linear View (Whole Mode)
View Location
   3580.0  –  3605.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP livG (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The Atpase Subunit Cysa Of The Putative Sulfate Atp-Binding Cassette (Abc) Transporter From Alicyclobacillus Acidocaldarius  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST High-affinity branched-chain amino acid transport ATP-binding protein livG (LIV-I protein G)  
         PSI-BLAST Phosphate import ATP-binding protein pstB
    nr     (database updated : 2007.02.20 )
         BLAST ATP-binding component of high-affinity branched-chain amino acid transport system [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    ATP_GTP_A    ABC_TRANSPORTER     

Other Cross-Reference
    COG COG0411E 
    EcoCyc livG 

MMBR References
J Biol Chem. 1990;265:11436-11443
Nucleotide sequence and genetic characterization reveal six essential genes for the LIV-I and LS transport systems of Escherichia coli.
Adams, M. D., L. M. Wagner, T. J. Graddis, R. Landick, T. K. Antonucci, A. L. Gibson, and D. L. Oxender.
J Bacteriol. 1975;122(3):957-65.
Transport of L-4-azaleucine in Escherichia coli.
Harrison LI, Christensen HN, Handlogten ME, Oxender DL, Quay SC. ( 238951 )
J Bacteriol. 1985;163(3):1196-202.
Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli.
Nazos PM, Mayo MM, Su TZ, Anderson JJ, Oxender DL. ( 2993238 )
Proc Natl Acad Sci U S A. 1980;77:1412-1416
Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli.
Oxender, D. L., J. J. Anderson, C. J. Daniels, R. Landick, R. P. Gunsalus, G. Zurawski, E. Selker, and C. Yanofsky.
J Bacteriol. 1980;144(1):36-44.
Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli K-12: isolation and properties of mutants defective in leucine-repressible transport activities.
Yamato I, Anraku Y. ( 6998958 )

Sequences
Amino acid
FASTA format 
0001 MSQPLLSVNG LMMRFGGLLA VNNVNLELYP QEIVSLIGPN GAGKTTVFNC LTGFYKPTGG TILLRDQHLE 
0071 GLPGQQIARM GVVRTFQHVR LFREMTVIEN LLVAQHQQLK TGLFSGLLKT PSFRRAQSEA LDRAATWLER 
0141 IGLLEHANRQ ASNLAYGDQR RLEIARCMVT QPEILMLDEP AAGLNPKETK ELDELIAELR NHHNTTILLI 
0211 EHDMKLVMGI SDRIYVVNQG TPLANGTPEQ IRNNPDVIRA YLGEA
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             gtttgatggt gctgatgatg atctggcgtc 
-070 cgcagggctt gctgcccatg acgcgcccgc aactgaagct gaaaaacggc gcagcgaaag gagagcaggc 
0001 atgagtcagc cattattatc tgttaacggc ctgatgatgc gcttcggcgg cctgctggcg gtgaacaacg 
0071 tcaatcttga actgtacccg caggagatcg tctcgttaat cggccctaac ggtgccggaa aaaccacggt 
0141 ttttaactgt ctgaccggat tctacaaacc caccggcggc accattttac tgcgcgatca gcacctggaa 
0211 ggtttaccgg ggcagcaaat tgcccgcatg ggcgtggtgc gcaccttcca gcatgtgcgt ctgttccgtg 
0281 aaatgacggt aattgaaaac ctgctggtgg cgcagcatca gcaactgaaa accgggctgt tctctggcct 
0351 gttgaaaacg ccatccttcc gtcgcgccca gagcgaagcg ctcgaccgcg ccgcgacctg gcttgagcgc 
0421 attggtttgc tggaacacgc caaccgtcag gcgagtaacc tggcctatgg tgaccagcgc cgtcttgaga 
0491 ttgcccgctg catggtgacg cagccggaga ttttaatgct cgacgaacct gcggcaggtc ttaacccgaa 
0561 agagacgaaa gagctggatg agctgattgc cgaactgcgc aatcatcaca acaccactat cttgttgatt 
0631 gaacacgata tgaagctggt gatgggaatt tcggaccgaa tttacgtggt caatcagggg acgccgctgg 
0701 caaacggtac gccggagcag atccgtaata acccggacgt gatccgtgcc tatttaggtg aggcataaga 
0771 tggaaaaagt catgttgtcc tttgacaaag tcagcgccca ctacggcaaa atccaggcgc tgcatgaggt 
0841 gagcctgcat atcaatcagg gcgagatt