MG1655
W3110
Search for
Japanese | English
Gene Report : livF
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL18 (D)  ,  OCL18-2 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  livF
Related strains
     Strains Search Search strains by gene name:  livF   Search strains by all related name:  livF b3454 ECK3438 f241 JW3419

General information  (Go to Linear View:)
 Gene Name livF  
 Alternative name b3454,ECK3438,f241,JW3419  
 Location, Length 3,590,747 - 3,591,460 (  -  ) ;   77.39 min ; 714 (bp) ,   237 (aa) Go to Linear View
 Product leucine/isoleucine/valine transporter subunit  
 Operon Name livKHMGF  
 Note ATP-binding component of leucine transport; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009063 - cellular amino acid catabolic process; GO_process: GO:0009098 - leucine biosynthetic process  
 Function transport; Transport of small molecules: Amino acids, amines  
 Gene Ontology GO:0000166 ; nucleotide binding ( livF )
GO:0005515 ; protein binding ( livF )
GO:0005524 ; ATP binding ( livF )
GO:0006810 ; transport ( livF )
GO:0006865 ; amino acid transport ( livF )
GO:0016887 ; ATPase activity ( livF )
GO:0017111 ; nucleoside-triphosphatase activity ( livF )
 PID 87082268  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) LIVF_ECOLI ( P22731 ; P76697 )
    -  Protein name High-affinity branched-chain amino acid transport ATP-binding protein livF  
    -  Synonyms LIV-I protein F  
    -  Gene name Name=livF; OrderedLocusNames=b3454;  

 Linear View (Whole Mode)
View Location
   3580.0  –  3605.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP livF (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Atp-Binding Cassette Of Multisugar Transporter From Pyrococcus Horikoshii Ot3 Complexed With Atp  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST High-affinity branched-chain amino acid transport ATP-binding protein livF  
         PSI-BLAST Phosphate import ATP-binding protein pstB
    nr     (database updated : 2007.02.20 )
         BLAST livF [Escherichia coli]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    ATP_GTP_A    LEUCINE_ZIPPER    ABC_TRANSPORTER     

Other Cross-Reference
    COG COG0410E 
    EcoCyc livF 

MMBR References
J Biol Chem. 1990;265:11436-11443
Nucleotide sequence and genetic characterization reveal six essential genes for the LIV-I and LS transport systems of Escherichia coli.
Adams, M. D., L. M. Wagner, T. J. Graddis, R. Landick, T. K. Antonucci, A. L. Gibson, and D. L. Oxender.

Sequences
Amino acid
FASTA format
0001 MEKVMLSFDK VSAHYGKIQA LHEVSLHINQ GEIVTLIGAN GAGKTTLLGT LCGDPRATSG RIVFDDKDIT 
0071 DWQTAKIMRE AVAIVPEGRR VFSRMTVEEN LAMGGFFAER DQFQERIKWV YELFPRLHER RIQRAGTMSG 
0141 GEQQMLAIGR ALMSNPRLLL LDEPSLGLAP IIIQQIFDTI EQLREQGMTI FLVEQNANQA LKLADRGYVL 
0211 ENGHVVLSDT GDALLANEAV RSAYLGG

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             atttacgtgg tcaatcaggg gacgccgctg 
-070 gcaaacggta cgccggagca gatccgtaat aacccggacg tgatccgtgc ctatttaggt gaggcataag 
0001 atggaaaaag tcatgttgtc ctttgacaaa gtcagcgccc actacggcaa aatccaggcg ctgcatgagg 
0071 tgagcctgca tatcaatcag ggcgagattg tcacgctgat tggcgcgaac ggggcgggga aaaccacctt 
0141 gctcggcacg ttatgcggcg atccgcgtgc caccagcggg cgaattgtgt ttgatgataa agacattacc 
0211 gactggcaga cagcgaaaat catgcgcgaa gcggtggcga ttgtcccgga agggcgtcgc gtcttctcgc 
0281 ggatgacggt ggaagagaac ctggcgatgg gcggtttttt tgctgaacgc gaccagttcc aggagcgcat 
0351 aaagtgggtg tatgagctgt ttccacgtct gcatgagcgc cgtattcagc gggcgggcac catgtccggc 
0421 ggtgaacagc agatgctggc gattggtcgt gcgctgatga gcaacccgcg tttgctactg cttgatgagc 
0491 catcgctcgg tcttgcgccg attatcatcc agcaaatttt cgacaccatc gagcagctgc gcgagcaggg 
0561 gatgactatc tttctcgtcg agcagaacgc caaccaggcg ctaaagctgg cggatcgcgg ctacgtgctg 
0631 gaaaacggcc atgtagtgct ttccgatact ggtgatgcgc tgctggcgaa tgaagcggtg agaagtgcgt 
0701 atttaggcgg gtaataacac gttgattgat agggagtcaa aagactcctt tgagacaggt gacaaatgta 
0771 aaattgcctg atgcgctgcg cttatcaggc ctactgggtg agtg