|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
OCL42
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
guaD
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
guaD
Search strains by all related name:
guaD b2883 ECK2879 JW5466 o439 o439b ygfP
|
General information (Go to Linear View: )
|
|
Gene Name
|
guaD
|
|
Alternative name
|
b2883,ECK2879,JW5466,o439,o439b,ygfP
|
|
Location, Length
|
3,023,788 - 3,025,107
(
+
)
;
65.17
min
;
1320
(bp) ,
439
(aa)
|
|
Product
|
guanine deaminase
|
|
Operon Name
|
xanQ-guaD-ygfQ
|
|
Note
|
|
|
Function
|
|
|
Gene Ontology
|
GO:0008270
;
zinc ion binding ( guaD )
GO:0008892
;
guanine deaminase activity ( guaD )
GO:0016787
;
hydrolase activity ( guaD )
GO:0016810
;
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ( guaD )
GO:0046872
;
metal ion binding ( guaD )
|
|
PID
|
1789249
|
EC number
(KEGG Pathway)
|
3.5.4.3
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
GUAD_ECOLI
(
P76641
;
Q46816
)
|
|
- Protein name
|
Guanine deaminase
|
|
- Synonyms
|
EC 3.5.4.3, Guanase, Guanine aminase, Guanine aminohydrolase, GAH
|
|
- Gene name
|
Name=guaD; OrderedLocusNames=b2883;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
guaD
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Guanine Deaminase From C. Acetobutylicum With Bound Guanine In The Active Site
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Guanine deaminase
|
|
PSI-BLAST
|
Urease alpha subunit
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
guanine deaminase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
|
| Sequences |
Amino acid
FASTA format
|
0001 MMSGEHTLKA VRGSFIDVTR TIDNPEEIAS ALRFIEDGLL LIKQGKVEWF GEWENGKHQI PDTIRVRDYR
0071 GKLIVPGFVD THIHYPQSEM VGAYGEQLLE WLNKHTFPTE RRYEDLEYAR EMSAFFIKQL LRNGTTTALV
0141 FGTVHPQSVD ALFEAASHIN MRMIAGKVMM DRNAPDYLLD TAESSYHQSK ELIERWHKNG RLLYAITPRF
0211 APTSSPEQMA MAQRLKEEYP DTWVHTHLCE NKDEIAWVKS LYPDHDGYLD VYHQYGLTGK NCVFAHCVHL
0281 EEKEWDRLSE TKSSIAFCPT SNLYLGSGLF NLKKAWQKKV KVGMGTDIGA GTTFNMLQTL NEAYKVLQLQ
0351 GYRLSAYEAF YLATLGGAKS LGLDDLIGNF LPGKEADFVV MEPTATPLQQ LRYDNSVSLV DKLFVMMTLG
0421 DDRSIYRTYV DGRLVYERN
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGATTTTATT AAATATTATC CTCCCTGGTG
-070 GCTACCGACA GGAAAACGTT CTGCCTGGTA TTACCTCAGC GGAAGAGATG GATTAACAGT AAAGGAGTCA
0001 atgatgtcag gagaacacac gttaaaagcg gtacgaggca gttttattga tgtcacccgt acgatcgata
0071 acccggaaga gattgcctct gcgctgcggt ttattgagga tggtttatta ctcattaaac agggaaaagt
0141 ggaatggttt ggcgaatggg aaaacggaaa gcatcaaatt cctgacacca ttcgcgtgcg cgactatcgc
0211 ggcaaactga tagtaccggg ctttgtcgat acacatatcc attatccgca aagtgaaatg gtgggggcct
0281 atggtgagca attgctggag tggttgaata aacacacctt ccctactgaa cgtcgttatg aggatttaga
0351 gtacgcccgc gaaatgtcgg cgttcttcat caagcagctt ttacgtaacg gaaccaccac ggcgctggtg
0421 tttggcactg ttcatccgca atctgttgat gcgctgtttg aagccgccag tcatatcaat atgcgtatga
0491 ttgccggtaa ggtgatgatg gaccgcaacg caccggatta tctgctcgac actgccgaaa gcagctatca
0561 ccaaagcaaa gaactgatcg aacgctggca caaaaatggt cgtctgctat atgcgattac gccacgcttc
0631 gccccgacct catctcctga acagatggcg atggcgcaac gcctgaaaga agaatatccg gatacgtggg
0701 tacataccca tctctgtgaa aacaaagatg aaattgcctg ggtgaaatcg ctttatcctg accatgatgg
0771 ttatctggat gtttaccatc agtacggcct gaccggtaaa aactgtgtct ttgctcactg cgtccatctc
0841 gaagaaaaag agtgggatcg tctcagcgaa accaaatcca gcattgcttt ctgtccgacc tccaaccttt
0911 acctcggcag cggcttattc aacttgaaaa aagcatggca gaagaaagtt aaagtgggca tgggaacgga
0981 tatcggtgcc ggaaccactt tcaacatgct gcaaacgctg aacgaagcct acaaagtatt gcaattacaa
1051 ggctatcgcc tctcggcata tgaagcgttt tacctggcca cgctcggcgg agcgaaatct ctgggccttg
1121 acgatttgat tggcaacttt ttacctggca aagaggctga tttcgtggtg atggaaccca ccgccactcc
1191 gctacagcag ctgcgctatg acaactctgt ttctttagtc gacaaattgt tcgtgatgat gacgttgggc
1261 gatgaccgtt cgatctaccg cacctacgtt gatggtcgtc tggtgtacga acgcaactaa TAATAAAACT
1331 TTAACATCCT CGTGAGGACA TCATTATGTC TGGAGACATC CTACAAACAC CGGACGCACC AAAGCCACAG
1401 GGCGCGCTGG ATAATTATTT
|
