MG1655
W3110
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Gene Report : fucA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion LD3-18-1 (LD)  ,  DE(relA-argA)216  ,  OCL44,45-4 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fucA
Related strains
     Strains Search Search strains by gene name:  fucA   Search strains by all related name:  fucA b2800 ECK2795 fucC JW2771 prd

General information  (Go to Linear View:)
 Gene Name fucA  
 Alternative name b2800,ECK2795,fucC,JW2771,prd  
 Location, Length 2,931,063 - 2,931,710 (  -  ) ;   63.17 min ; 648 (bp) ,   215 (aa) Go to Linear View
 Product L-fuculose-1-phosphate aldolase  
 Operon Name fucAO  
 Note GO_process: GO:0016052 - carbohydrate catabolic process  
 Function enzyme; Degradation of small molecules: Carbon compounds  
 Gene Ontology GO:0005515 ; protein binding ( fucA )
GO:0005975 ; carbohydrate metabolic process ( fucA )
GO:0006004 ; fucose metabolic process ( fucA )
GO:0008270 ; zinc ion binding ( fucA )
GO:0008738 ; L-fuculose-phosphate aldolase activity ( fucA )
GO:0016829 ; lyase activity ( fucA )
GO:0046872 ; metal ion binding ( fucA )
 PID 1789164  
 EC number
  (KEGG Pathway)
 
4.1.2.17  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) FUCA_ECOLI ( P11550 )
    -  Protein name L-fuculose phosphate aldolase  
    -  Synonyms EC 4.1.2.17, L-fuculose-1-phosphate aldolase  
    -  Gene name Name=fucA; Synonyms=fucC, prd; OrderedLocusNames=b2800, SF2814, S3009;  

 Linear View (Whole Mode)
View Location
   2920.0  –  2945.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fucA (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain P, L-Fuculose 1-Phosphate Aldolase From Escherichia Coli Mutant E73q  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST L-fuculose phosphate aldolase (L-fuculose-1-phosphate aldolase)  
         PSI-BLAST L-fuculose phosphate aldolase
    nr     (database updated : 2007.02.20 )
         BLAST L-fuculose phosphate aldolase [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    PROKAR_LIPOPROTEIN     

Other Cross-Reference
    COG COG0235G 
    EcoCyc fucA 

MMBR References
Nucleic Acids Res. 1989;17(12):4883-4.
The nucleotide sequence of Escherichia coli genes for L-fucose dissimilation.
Lu Z, Lin EC. ( 2664711 )
J Bacteriol. 1982;152(1):120-5.
Analysis of lambda insertions in the fucose utilization region of Escherichia coli K-12: use of lambda fuc and lambda argA transducing bacteriophages to partially order the fucose utilization genes.
Skjold AC, Ezekiel DH. ( 6214544 )
J Bacteriol. 1988;170(5):2352-8.
A mutant crp allele that differentially activates the operons of the fuc regulon in Escherichia coli.
Zhu Y, Lin EC. ( 2834341 )
J Bacteriol. 1984;157(3):984-6.
Clustering of genes for L-fucose dissimilation by Escherichia coli.
Chakrabarti T, Chen YM, Lin ECC. ( 6321453 )
Mol Gen Genet. 1987;210(2):331-7.
The organization of the fuc regulon specifying L-fucose dissimilation in Escherichia coli K12 as determined by gene cloning.
Chen YM, Zhu Y, Lin ECC. ( 3325779 )
J Bacteriol. 1989;171(11):6097-105.
Constitutive activation of the fucAO operon and silencing of the divergently transcribed fucPIK operon by an IS5 element in Escherichia coli mutants selected for growth on L-1,2-propanediol.
Chen YM, Lu Z, Lin ECC. ( 2553671 )

Sequences
Amino acid
FASTA format
0001 MERNKLARQI IDTCLEMTRL GLNQGTAGNV SVRYQDGMLI TPTGIPYEKL TESHIVFIDG NGKHEEGKLP 
0071 SSEWRFHMAA YQSRPDANAV VHNHAVHCTA VSILNRSIPA IHYMIAAAGG NSIPCAPYAT FGTRELSEHV 
0141 ALALKNRKAT LLQHHGLIAC EVNLEKALWL AHEVEVLAQL YLTTLAITDP VPVLSDEEIA VVLEKFKTYG 
0211 LRIEE

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ttgttaatca ggaagaagat ggtgggtaat 
-070 taaacggcta attcaatagt gtgaaaggaa caacattatt gccctgtttt gaatcagaga gaggtagcta 
0001 atggaacgaa ataaacttgc tcgtcagatt attgacactt gcctggaaat gacccgcctg ggactgaacc 
0071 aggggacagc ggggaacgtc agtgtacgtt atcaggatgg gatgctgatt acgcctacag gcattccata 
0141 tgaaaaactg acggagtcgc atattgtctt tattgatggc aacggtaaac atgaggaagg aaagctcccc 
0211 tcaagcgaat ggcgtttcca tatggcagcc tatcaaagca gaccggatgc caacgcggtt gttcacaatc 
0281 atgccgttca ttgcacggca gtttccattc ttaaccgatc gatccccgct attcactaca tgattgcggc 
0351 ggctggcggt aattctattc cttgcgcgcc ttatgcgacc tttggaacac gcgaactttc tgaacatgtt 
0421 gcgctggctc tcaaaaatcg taaggcaact ttgttacaac atcatgggct tatcgcttgt gaggtgaatc 
0491 tggaaaaagc gttatggctg gcgcatgaag ttgaagtgct ggcgcaactt tacctgacga ccctggcgat 
0561 tacggacccg gtgccagtgc tgagcgatga agagattgcc gtagtgctgg agaaattcaa aacctatggg 
0631 ttacgaattg aagagtaatt tcgtaaagca acaaggagaa ggatgatggc taacagaatg attctgaacg 
0701 aaacggcatg gtttggtcgg ggtgctgttg gggctttaac cgatgagg