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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
|
J Bacteriol. 1998;180(11):2915-23.
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
Diaz E, Ferrandez A, Garcia JL.
(
9603882
)
|
|
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Deletion
|
OCL55
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
hcaB
|
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Related strains
|
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Strains Search
|
Search strains by gene name:
hcaB
Search strains by all related name:
hcaB b2541 ECK2538 JW2525 o270 phdD yfhX
|
General information (Go to Linear View: )
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Gene Name
|
hcaB
|
|
Alternative name
|
b2541,ECK2538,JW2525,o270,phdD,yfhX
|
|
Location, Length
|
2,669,247 - 2,670,059
(
+
)
;
57.53
min
;
813
(bp) ,
270
(aa)
|
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Product
|
2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
|
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Operon Name
|
hcaEFCBD
|
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Note
|
GO_process: GO:0016052 - carbohydrate catabolic process
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Function
|
enzyme; Degradation of small molecules: Carbon compounds
|
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( hcaB )
GO:0005488
;
binding ( hcaB )
GO:0008152
;
metabolic process ( hcaB )
GO:0016491
;
oxidoreductase activity ( hcaB )
GO:0019439
;
aromatic compound catabolic process ( hcaB )
|
|
PID
|
1788891
|
EC number
(KEGG Pathway)
|
1.3.1.-
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
HCAB_ECOLI
(
P77646
;
P76995
)
|
|
- Protein name
|
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase
|
|
- Synonyms
|
EC 1.3.1.-
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|
- Gene name
|
Name=hcaB; Synonyms=phdD; OrderedLocusNames=b2541;
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MMBR References
|
Ph.D. thesis. University of Minnesota, Minneapolis-St. Paul. 1983
The degradation of 3-phenylpropionic acid by Escherichia coli.
Burlingame, R. P.
|
J Bacteriol. 1986;168(1):55-64.
Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation.
Burlingame RP, Wyman L, Chapman PJ.
(
3531186
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MSDLHNESIF ITGGGSGLGL ALVERFIEEG AQVATLELSA AKVASLRQRF GEHILAVEGN VTCYADYQRA
0071 VDQILTRSGK LDCFIGNAGI WDHNASLVNT PAETLETGFH ELFNVNVLGY LLGAKACAPA LIASEGSMIF
0141 TLSNAAWYPG GGGPLYTASK HAATGLIRQL AYELAPKVRV NGVGPCGMAS DLRGPQALGQ SETSIMQSLT
0211 PEKIAAILPL QFFPQPADFT GPYVMLTSRR NNRALSGVMI NADAGLAIRG IRHVAAGLDL
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CGGGGAAAGC GTTATGCCTG CCCGCCACCG
-070 ATCCGCTCAC CACTTATCCA GTACACGTTG AAGGTGGTGA CATTTTCATC GACTTACCGG AGGCGCAGCC
0001 atgagcgatc tgcataacga gtccattttt attaccggcg gcggatcggg attagggctg gcgctggtcg
0071 agcgatttat cgaagaaggc gcgcaggttg ccacgctgga actgtcggcg gcaaaagtcg ccagtctgcg
0141 tcagcgattt ggcgaacata ttctggcggt ggaaggtaac gtgacctgtt atgccgatta tcaacgcgcg
0211 gtcgatcaga tcctgactcg ttccggcaag ctggattgtt ttatcggcaa tgcaggcatc tgggatcaca
0281 atgcctcact ggttaatact cccgcagaga cgctcgaaac cggcttccac gagctgttta acgtcaatgt
0351 tctcggttac ctgctgggcg caaaagcctg cgctccggcg ttaatcgcca gtgaaggcag catgattttc
0421 acactgtcaa atgccgcctg gtatcctggc ggcggtggcc cgctgtacac cgccagtaaa catgccgcaa
0491 ccggacttat tcgccaactg gcttatgaac tggcaccgaa agtgcgggtg aatggcgtcg gcccgtgtgg
0561 tatggccagc gacctgcgcg gcccacaggc gctcgggcaa agtgaaacct cgataatgca gtctctgacg
0631 ccggagaaaa ttgccgccat tttaccgctg caatttttcc cgcaaccggc ggattttacg gggccgtatg
0701 tgatgttgac atcgcggcgc aataatcgcg cattaagcgg tgtgatgatc aacgctgatg cgggtttagc
0771 gattcgcggc attcgccacg tagcggctgg gctggatctt taaGGAAGCA CGATGAAAGA AAAAACGATC
0841 ATTATTGTCG GTGGCGGGCA AGCGGCGGCA ATGGCTGCGG CCTCGCTACG CCAGCAAGGG TTCACCGGTG
0911 AGC
|
