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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCL60-21
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
cysA
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Related strains
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Strains Search
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Search strains by gene name:
cysA
Search strains by all related name:
cysA b2422 ECK2417 JW2415
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General information (Go to Linear View: )
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Gene Name
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cysA
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Alternative name
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b2422,ECK2417,JW2415
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Location, Length
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2,537,739 - 2,538,836
(
-
)
;
54.70
min
;
1098
(bp) ,
365
(aa)
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Product
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sulfate/thiosulfate transporter subunit
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Operon Name
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cysPUWAM
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Note
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ATP-binding component of sulfate permease A protein; chromate resistance; ATP-binding component of ABC superfamily; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0015419 - sulfate transmembrane-transporting ATPase activity; GO_process: GO:0006790 - sulfur metabolic process; GO_process: GO:0042493 - response to drug
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Function
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transport; Transport of small molecules: Anions
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Gene Ontology
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GO:0000166
;
nucleotide binding ( cysA )
GO:0005215
;
transporter activity ( cysA )
GO:0005524
;
ATP binding ( cysA )
GO:0005886
;
plasma membrane ( cysA )
GO:0006810
;
transport ( cysA )
GO:0008272
;
sulfate transport ( cysA )
GO:0015419
;
sulfate transmembrane-transporting ATPase activity ( cysA )
GO:0016020
;
membrane ( cysA )
GO:0016787
;
hydrolase activity ( cysA )
GO:0016820
;
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ( cysA )
GO:0016887
;
ATPase activity ( cysA )
GO:0017111
;
nucleoside-triphosphatase activity ( cysA )
GO:0042626
;
ATPase activity, coupled to transmembrane movement of substances ( cysA )
GO:0043190
;
ATP-binding cassette (ABC) transporter complex ( cysA )
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PID
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1788761
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EC number
(KEGG Pathway)
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3.6.3.25
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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CYSA_ECOLI
(
P16676
;
P77693
)
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- Protein name
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Sulfate/thiosulfate import ATP-binding protein cysA
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- Synonyms
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EC 3.6.3.25, Sulfate-transporting ATPase
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- Gene name
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Name=cysA; OrderedLocusNames=b2422;
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MMBR References
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J Biol Chem. 1987;262:16241-16253
Sugar transport by the bacterial phosphotransferase system. Molecular cloning and structural analysis of the Escherichia coli ptsH, ptsI and crr genes.
Saffen, D. W., K. A. Presper, T. L. Doering, and S. Roseman.
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J Gen Microbiol. 1987;133(10):2719-25.
Identification of the Escherichia coli cysM gene encoding O-acetylserine sulphydrylase B by cloning with mini-Mu-lac containing a plasmid replicon.
Sirko AE, Zatyka M, Hulanicka MD.
(
3329675
)
|
Arch Biochem Biophys. 1973;156(2):595-603.
Sulfate and selenate uptake and transport in wild and in two selenate-tolerant strains of Escherichia coli K-12.
Springer SE, Huber RE.
(
4578122
)
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J Biol Chem. 1994;269:5225-5229
Involvement of FtsH in protein assembly into and through the membrane. II. Dominant mutations affecting FtsH functions.
Akiyama, Y., Y. Shirai, and K. Ito.
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J Mol Biol. 1990;214(4):825-43.
Precise mapping and comparison of two evolutionarily related regions of the Escherichia coli K-12 chromosome. Evolution of valU and lysT from an ancestral tRNA operon.
Brun YV, Breton R, Lanouette P, Lapointe J.
(
2201776
)
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| Sequences |
Amino acid
FASTA format
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0001 MSIEIANIKK SFGRTQVLND ISLDIPSGQM VALLGPSGSG KTTLLRIIAG LEHQTSGHIR FHGTDVSRLH
0071 ARDRKVGFVF QHYALFRHMT VFDNIAFGLT VLPRRERPNA AAIKAKVTKL LEMVQLAHLA DRYPAQLSGG
0141 QKQRVALARA LAVEPQILLL DEPFGALDAQ VRKELRRWLR QLHEELKFTS VFVTHDQEEA TEVADRVVVM
0211 SQGNIEQADA PDQVWREPAT RFVLEFMGEV NRLQGTIRGG QFHVGAHRWP LGYTPAYQGP VDLFLRPWEV
0281 DISRRTSLDS PLPVQVLEAS PKGHYTQLVV QPLGWYNEPL TVVMHGDDAP QRGERLFVGL QHARLYNGDE
0351 RIETRDEELA LAQSA
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gcgctgttaa cgctgatggc gattatcacc
-070 ctgtttttaa aaagtatgtt gcagtggcgc ctggagaatc aggaaaaacg cgcacagcag gaggaacatc
0001 atgagcattg agattgccaa tattaagaag tcgtttggtc gcacccaggt gctgaacgat atctcactgg
0071 atattccttc aggtcagatg gtcgcgttgc tggggccgtc cggttccggg aaaaccacgc tgctgcgcat
0141 tatcgccggg ctggagcatc aaaccagcgg gcatattcgc ttccacggca ccgacgtgag ccgcctgcac
0211 gcacgtgatc gtaaagtcgg tttcgtgttc cagcattacg cgctgttccg ccatatgacg gtgttcgaca
0281 atatcgcttt tggcctgacg gtgctgccgc gtcgcgagcg cccgaatgcc gcagccatca aagcgaaagt
0351 gacaaaattg ctggaaatgg tccagcttgc ccatctggcg gatcgttatc cggcgcagct ttccggcggc
0421 cagaaacagc gcgtggcgct ggcgcgcgcg ctggctgtgg aaccgcaaat tctgctgctt gatgaaccgt
0491 ttggcgcgct ggatgcgcag gtgcgtaaag agctgcgtcg ctggctgcgt caactccatg aagaactaaa
0561 attcaccagc gtttttgtga cccacgatca ggaagaagcg accgaagtag ctgatcgtgt agttgtgatg
0631 agccagggca atattgaaca ggctgacgcg ccggatcagg tatggcgcga accggcgacc cgttttgtgc
0701 tcgaatttat gggcgaagtg aaccgcctgc agggaaccat tcgcggcggg cagttccatg ttggcgcgca
0771 tcgctggccg ctgggctaca cacctgcgta tcaggggccg gtggatctct tcctgcgccc ttgggaagtg
0841 gatatcagcc gccgtaccag cctcgattcg ccgctgccgg tacaggtact ggaagccagc ccgaaaggtc
0911 actacaccca attagtggtg cagccgctgg ggtggtacaa cgaaccgctg acggtcgtga tgcatggcga
0981 cgatgccccg cagcgtggcg agcgtttatt cgttggtctg caacatgcgc ggctgtataa cggcgacgag
1051 cgtatcgaaa cccgcgatga ggaacttgct ctcgcacaaa gcgcctgata ggttgagtga atgttaaacg
1121 cccggaggcg cttcccgcga tccgggcttt ttaatggcaa ggtttgtaac ctgtagacct gataagacgc
1191 gcaagcgt
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