|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
16-1-2
(LD)
,
DE(sbcB-rfb)202
,
DE(his-dcd)453
,
OCL74-2,75-5 (LD 16-1-2_CRS)
(D)
,
OCL74-2,75-6 (LD 16-1-2_P/O)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
cpsG
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
cpsG
Search strains by all related name:
cpsG b2048 ECK2042 JW2033 manB rfbK
|
General information (Go to Linear View: )
|
|
Gene Name
|
cpsG
|
|
Alternative name
|
b2048,ECK2042,JW2033,manB,rfbK
|
|
Location, Length
|
2,119,633 - 2,121,003
(
-
)
;
45.68
min
;
1371
(bp) ,
456
(aa)
|
|
Product
|
phosphomannomutase
|
|
Operon Name
|
wcaCDEF-gmd-fcl-gmm-wcaI-cpsBG-wcaJ-wzxC
|
|
Note
|
GO_function: GO:0042280 - cell surface antigen activity, host-interacting; GO_process: GO:0009226 - nucleotide-sugar biosynthetic process; GO_process: GO:0009242 - colanic acid biosynthetic process; GO_process: GO:0009269 - response to desiccation
|
|
Function
|
enzyme; Central intermediary metabolism: Pool, multipurpose conversions
|
|
Gene Ontology
|
GO:0000287
;
magnesium ion binding ( manB )
GO:0004615
;
phosphomannomutase activity ( manB )
GO:0005975
;
carbohydrate metabolic process ( manB )
GO:0009103
;
lipopolysaccharide biosynthetic process ( manB )
GO:0016853
;
isomerase activity ( manB )
GO:0016868
;
intramolecular transferase activity, phosphotransferases ( manB )
GO:0046872
;
metal ion binding ( manB )
|
|
PID
|
1788361
|
EC number
(KEGG Pathway)
|
5.4.2.8
|
|
SWISS-PROT
(
Show details
[
4
more]
)
|
Entry name(Acc.no)
|
MANB_ECO57
(
O85343
)
|
|
- Protein name
|
Phosphomannomutase
|
|
- Synonyms
|
EC 5.4.2.8, PMM
|
|
- Gene name
|
Name=manB; OrderedLocusNames=z3194, ECs2835;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
cpsG
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Pyrococcus Horikoshii PhosphomannomutasePHOSPHOGLUCOMUTASE COMPLEXED WITH MG2+
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Phosphomannomutase
|
|
PSI-BLAST
|
Phosphoglucosamine mutase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
phosphomannomutase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
GLYCOSAMINOGLYCAN
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
RGD
PGM_PMM
|
|
MMBR References
|
J Bacteriol. 1994;176:3126-3139
Cloning and analysis of duplicated rfbM and rfbK genes involved in the formation of GDP-mannose in Escherichia coli 09:K30 and participation of rfb genes in the synthesis of the group I K30 capsular polysaccharide.
Jayaratne, P., D. Bronner, P. R. MacLachlan, C. Dodgson, N. Kido, and C. Whitfield.
|
| Sequences |
Amino acid
FASTA format
|
0001 MKKLTCFKAY DIRGKLGEEL NEDIAWRIGR AYGEFLKPKT IVLGGDVRLT SETLKLALAK GLQDAGVDVL
0071 DIGMSGTEEI YFATFHLGVD GGIEVTASHN PMDYNGMKLV REGARPISGD TGLRDVQRLA EANDFPPVDE
0141 TKRGRYQQIN LRDAYVDHLF GYINVKNLTP LKLVINSGNG AAGPVVDAIE ARFKALGAPV ELIKVHNTPD
0211 GNFPNGIPNP LLPECRDDTR NAVIKHGADM GIAFDGDFDR CFLFDEKGQF IEGYYIVGLL AEAFLEKNPG
0281 AKIIHDPRLS WNTVDVVTAA GGTPVMSKTG HAFIKERMRK EDAIYGGEMS AHHYFRDFAY CDSGMIPWLL
0351 VAELVCLKDK TLGELVRDRM AAFPASGEIN SKLAQPVEAI NRVEQHFSRE ALAVDRTDGI SMTFADWRFN
0421 LRTSNTEPVV RLNVESRGDV PLMEARTRTL LTLLNE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgcatcaggc aatgaatgcg aaaccgcggt
-070 gtaaataacg acaaaaataa aattggccgc ttcggtcagg gccaactatt gcctgaaaaa gggtaacgat
0001 atgaaaaaat taacctgctt taaagcctat gatattcgcg ggaaattagg cgaagaactg aatgaagata
0071 tcgcctggcg cattggtcgc gcctatggcg aatttctcaa accgaaaacc attgtgttag gcggtgatgt
0141 ccgcctcacc agcgaaacct taaaactggc gctggcgaaa ggtttacagg atgcgggcgt tgacgtgctg
0211 gatattggta tgtccggcac cgaagagatc tatttcgcca cgttccatct cggcgtggat ggcggcattg
0281 aagttaccgc cagccataat ccgatggatt ataacggcat gaagctggtt cgcgaggggg ctcgcccgat
0351 cagcggagat accggactgc gcgacgtcca gcgtctggct gaagccaacg actttcctcc cgtcgatgaa
0421 accaaacgcg gtcgctatca gcaaatcaac ctgcgtgacg cttacgttga tcacctgttc ggttatatca
0491 atgtcaaaaa cctcacgccg ctcaagctgg tgatcaactc cgggaacggc gcagcgggtc cggtggtgga
0561 cgccattgaa gcccgcttta aagccctcgg cgcgcccgtg gaattaatca aagtgcacaa cacgccggac
0631 ggcaatttcc ccaacggtat tcctaaccca ctactgccgg aatgccgcga cgacacccgc aatgcggtca
0701 tcaaacacgg cgcggatatg ggcattgctt ttgatggcga ttttgaccgc tgtttcctgt ttgacgaaaa
0771 agggcagttt attgagggct actacattgt cggcctgttg gcagaagcat tcctcgaaaa aaatcccggc
0841 gcgaagatca tccacgatcc acgtctctcc tggaacaccg ttgatgtggt gactgccgca ggtggcacgc
0911 cggtaatgtc gaaaaccgga cacgccttta ttaaagaacg tatgcgcaag gaagacgcca tctatggtgg
0981 cgaaatgagc gcccaccatt acttccgtga tttcgcttac tgcgacagcg gcatgatccc gtggctgctg
1051 gtcgccgaac tggtgtgcct gaaagataaa acgctgggcg aactggtacg cgaccggatg gcggcgtttc
1121 cggcaagcgg tgagatcaac agcaaactgg cgcaacccgt tgaggcgatt aaccgcgtgg aacagcattt
1191 tagccgtgag gcgctggcgg tggatcgcac cgatggcatc agcatgacct ttgccgactg gcgctttaac
1261 ctgcgcacct ccaataccga accggtggtg cgcctgaatg tggaatcgcg cggtgatgtg ccgctgatgg
1331 aagcgcgaac gcgaactctg ctgacgttgc tgaacgagta atgtcggatc ttcccttacc ccactgcggg
1401 taaggggcta ataacaggaa caacgatgac aaatctaaaa aagcgcgagc gagcgaaaac caatgcatcg
1471 t
|
