MG1655
W3110
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Gene Report : exoX
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Biol Chem. 1999;274(42):30094-100.
Exonuclease X of Escherichia coli. A novel 3'-5' DNase and Dnaq superfamily member involved in DNA repair.
Viswanathan M, Lovett ST. ( 10514496 )
     Deletion  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  exoX
Related strains
     Strains Search Search strains by gene name:  exoX   Search strains by all related name:  exoX b1844 ECK1845 JW1833 o220 yobC

General information  (Go to Linear View:)
 Gene Name exoX  
 Alternative name b1844,ECK1845,JW1833,o220,yobC  
 Location, Length 1,924,144 - 1,924,806 (  +  ) ;   41.47 min ; 663 (bp) ,   220 (aa) Go to Linear View
 Product exodeoxyribonuclease 10; DNA exonuclease X  
 Operon Name yobB-exoX  
 Note GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006308 - DNA catabolic process; GO_process: GO:0006281 - DNA repair  
 Function  
 Gene Ontology GO:0000287 ; magnesium ion binding ( exoX )
GO:0003676 ; nucleic acid binding ( exoX )
GO:0004518 ; nuclease activity ( exoX )
GO:0004527 ; exonuclease activity ( exoX )
GO:0005622 ; intracellular ( exoX )
GO:0006281 ; DNA repair ( exoX )
GO:0006974 ; response to DNA damage stimulus ( exoX )
GO:0016787 ; hydrolase activity ( exoX )
 PID 1788149  
 EC number
  (KEGG Pathway)   		3.1.11.-  
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) EXOX_ECOLI ( P76281 )
    -  Protein name Exodeoxyribonuclease X  
    -  Synonyms EC 3.1.11.-, Exonuclease X, Exo X  
    -  Gene name Name=exoX; OrderedLocusNames=b1844, c2254;  

 Linear View (Whole Mode)
View Location
   1915.0  –  1940.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP exoX (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The N-Terminal Exonuclease Domain Of The Epsilon Subunit Of E.Coli Dna Polymerase Iii At Ph 8.5  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Exodeoxyribonuclease 10 (Exodeoxyribonuclease X) (Exonuclease X) (Exo X)  
         PSI-BLAST DNA polymerase III polC-type
    nr     (database updated : 2007.02.20 )
         BLAST exodeoxyribonuclease X [Escherichia coli CFT073]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    COG COG0847L 
    EcoCyc exoX 

Sequences
Amino acid
FASTA format 
0001 MLRIIDTETC GLQGGIVEIA SVDVIDGKIV NPMSHLVRPD RPISPQAMAI HRITEAMVAD KPWIEDVIPH 
0071 YYGSEWYVAH NASFDRRVLP EMPGEWICTM KLARRLWPGI KYSNMALYKT RKLNVQTPPG LHHHRALYDC 
0141 YITAALLIDI MNTSGWTAEQ MADITGRPSL MTTFTFGKYR GKAVSDVAER DPGYLRWLFN NLDSMSPELR 
0211 LTLKHYLENT
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             CCGATCGTGG TTCATTATTG TTAGTCGGTC 
-070 AGCGTTCATC ACAGGGTTGG CAAGGCGATA TCATTCCATT ACGCTAGGCT TTTTCGGCCT GGAGCATGCC 
0001 atgttgcgca ttatcgatac agaaacctgc ggtttgcagg gagggatcgt tgagattgcc tctgttgatg 
0071 tcattgacgg aaaaatcgtc aaccccatga gccacctggt gcgccccgat cgtcctatta gtccacaagc 
0141 gatggcgatt catcgcatca ccgaagccat ggtcgccgat aaaccgtgga ttgaagatgt gatcccacac 
0211 tattacggta gtgaatggta tgtcgcgcat aacgccagct ttgaccgccg cgtactgcct gagatgcccg 
0281 gtgagtggat ttgcactatg aaactggccc gtcgtttgtg gcctgggatc aagtacagca atatggcgtt 
0351 atataaaaca cgcaagctca atgtacagac gccgccgggc ctgcatcatc accgcgcgtt gtatgactgt 
0421 tatatcaccg ccgcgttgct tatcgatatt atgaacacct ccggctggac ggcagaacag atggccgata 
0491 tcaccggacg tccgtcgttg atgacgacct tcacctttgg caaataccgt ggcaaagcgg tttccgacgt 
0561 tgccgaacgc gatccgggct atctgcgctg gttatttaat aacctggaca gcatgagccc ggagctgcgt 
0631 ttaacactga aacattatct ggaaaatact tagTCCGCAG GCGTAGCGGG TAATGTTCCC TGCGCCAGCG 
0701 CGACCAGAAA AGCATATTCC ATCGCTACGC CTTCGTACGA TTTAAAGCGA CCAGATTTAC CGC