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PEC Original Annotations
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|
Essentiality
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Class
|
non-essential
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References (PMID)
|
|
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Deletion
|
OCL83
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
dmlA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
dmlA
Search strains by all related name:
dmlA b1800 ECK1798 JW1789 o361 yeaU
|
General information (Go to Linear View: )
|
|
Gene Name
|
dmlA
|
|
Alternative name
|
b1800,ECK1798,JW1789,o361,yeaU
|
|
Location, Length
|
1,879,936 - 1,881,021
(
+
)
;
40.52
min
;
1086
(bp) ,
361
(aa)
|
|
Product
|
D-malate oxidase, NAD-dependent; probable tartrate dehydrogenase
|
|
Operon Name
|
dmlA
|
|
Note
|
putative tartrate dehydrogenase; GO_process: GO:0006113 - fermentation
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Function
|
putative enzyme; Not classified
|
|
Gene Ontology
|
GO:0005515
;
protein binding ( yeaU )
GO:0005737
;
cytoplasm ( yeaU )
GO:0008152
;
metabolic process ( yeaU )
GO:0009027
;
tartrate dehydrogenase activity ( yeaU )
GO:0016491
;
oxidoreductase activity ( yeaU )
GO:0016616
;
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ( yeaU )
GO:0016829
;
lyase activity ( yeaU )
GO:0046553
;
D-malate dehydrogenase (decarboxylating) activity ( yeaU )
GO:0050319
;
tartrate decarboxylase activity ( yeaU )
GO:0051287
;
NAD binding ( yeaU )
|
|
PID
|
1788101
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
TTUC_ECOLI
(
P76251
;
O08474; O08475
)
|
|
- Protein name
|
Probable tartrate dehydrogenase
|
|
- Synonyms
|
EC 1.1.1.93, TDH
|
|
- Gene name
|
Name=yeaU; OrderedLocusNames=b1800;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
yeaU
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, 3-Isopropylmalate Dehydrogenase From Escherichia Coli
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Probable tartrate dehydrogenase/decarboxylase
|
|
PSI-BLAST
|
3-isopropylmalate dehydrogenase
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
predicted dehydrogenase [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
IDH_IMDH
|
| Sequences |
Amino acid
FASTA format
|
0001 MMKTMRIAAI PGDGIGKEVL PEGIRVLQAA AERWGFALSF EQMEWASCEY YSHHGKMMPD DWHEQLSRFD
0071 AIYFGAVGWP DTVPDHISLW GSLLKFRREF DQYVNLRPVR LFPGVPCPLA GKQPGDIDFY VVRENTEGEY
0141 SSLGGRVNEG TEHEVVIQES VFTRRGVDRI LRYAFELAQS RPRKTLTSAT KSNGLAISMP YWDERVEAMA
0211 ENYPEIRWDK QHIDILCARF VMQPERFDVV VASNLFGDIL SDLGPACTGT IGIAPSANLN PERTFPSLFE
0281 PVHGSAPDIY GKNIANPIAT IWAGAMMLDF LGNGDERFQQ AHNGILAAIE EVIAHGPKTP DMKGNATTPQ
0351 VADAICKIIL R
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 TTCGTGTTTT ATGTTTCACC AGTTACGGGG
-070 ATTAATTCCT TTTCAGTCAA TTATAGGATG GTGATGTTGT CAATTTTGAT GGTCAGGAAG TGAGAACCCA
0001 atgatgaaaa cgatgcgtat tgctgcgatc ccgggagacg ggattggcaa agaagtcctt cctgaaggga
0071 ttcgcgtgtt acaggctgcc gctgagcgct ggggcttcgc cttgagtttt gagcaaatgg agtgggcgag
0141 ctgcgagtat tacagccatc acggtaaaat gatgccggac gactggcatg agcaacttag ccgtttcgac
0211 gccatctatt ttggtgccgt cggctggccg gataccgttc cggaccatat ttcgttgtgg ggttcgctgc
0281 tgaaatttcg tcgtgaattc gaccagtacg tcaacctgcg cccggttcgt ctctttcctg gcgttccctg
0351 cccgctggcg ggaaaacagc ctggcgacat cgatttttac gtggtcaggg aaaacaccga aggcgaatat
0421 tcctcgctcg gcggtagagt gaatgaaggt acagagcatg aagtcgtcat tcaggaatcg gtatttaccc
0491 gccgtggtgt cgatcgcatt ttgcgttatg ccttcgaact tgcgcaaagc cgtccacgta agacactaac
0561 ttctgccact aaatcgaacg gtttagccat cagcatgccg tactgggatg agcgagtgga agcaatggcc
0631 gagaattacc cggagatccg ctgggacaag cagcatattg atattctctg cgcgcgtttt gtgatgcagc
0701 cggaacgatt cgatgtggtg gtggcgtcca atttgtttgg cgatatcctt tccgatcttg gcccggcctg
0771 caccggcacc attggcattg ccccatccgc caacctgaat ccggaacgca ctttcccgtc gctcttcgag
0841 cctgtccacg gttccgcgcc ggatatctac gggaaaaata ttgctaaccc tatcgccacg atttgggccg
0911 gggcaatgat gctcgatttt ctcggcaatg gcgatgagcg tttccagcaa gcgcataacg gtattctggc
0981 agcaattgaa gaagtgattg ctcacgggcc gaaaacacct gatatgaaag gcaatgccac cacgccacag
1051 gttgccgacg cgatttgcaa aattattttg cgttaaGGTC AAACCAGTTT ATTTGAACCG CGTCACTGAC
1121 GCGGTTTTTT TATTCGTTCT TTGCAGTAAA TAACCTGCGT CATTTCACCT TTTATTGTTT CCGTTT
|
