MG1655
W3110
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Gene Report : folM
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)  
     Deletion DE(PLK1608)  ,  OCL90-2 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  folM
Related strains
     Strains Search Search strains by gene name:  folM   Search strains by all related name:  folM b1606 ECK1601 JW1598 o240 ydgB

General information  (Go to Linear View:)
 Gene Name folM  
 Alternative name b1606,ECK1601,JW1598,o240,ydgB  
 Location, Length 1,679,000 - 1,679,722 (  +  ) ;   36.19 min ; 723 (bp) ,   240 (aa) Go to Linear View
 Product dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme  
 Operon Name ydgI-folM  
 Note putative oxidoreductase  
 Function enzyme; tetrahydromonapterin synthesis  
 Gene Ontology GO:0003824 ; catalytic activity ( ydgB )
GO:0005488 ; binding ( ydgB )
GO:0008152 ; metabolic process ( ydgB )
GO:0016491 ; oxidoreductase activity ( ydgB )
 PID 1787891  
 EC number
  (KEGG Pathway)   		1.5.1.3  
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) YDGB_ECOLI ( P52109 ; P77386 )
    -  Protein name Hypothetical oxidoreductase ydgB  
    -  Synonyms EC 1.-.-.-  
    -  Gene name Name=ydgB; OrderedLocusNames=b1606, z2606, ECs2312;  

 Linear View (Whole Mode)
View Location
   1670.0  –  1695.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP folM (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Orf 1438 A Putative GlucoseRIBITOL Dehydrogenase From Clostridium Thermocellum  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Hypothetical oxidoreductase ydgB  
         PSI-BLAST 3-oxoacyl-[acyl-carrier-protein] reductase
    nr     (database updated : 2007.02.20 )
         BLAST short chain dehydrogenase [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    ADH_SHORT     

Other Cross-Reference
    COG COG1028IQR 
    EcoCyc folM 

Sequences
Amino acid
FASTA format 
0001 MGKTQPLPIL ITGGGRRIGL ALAWHFINQK QPVIVSYRTH YPAIDGLINA GAQCIQADFS TNDGVMAFAD 
0071 EVLKSTHGLR AILHNASAWM AEKPGAPLAD VLACMMQIHV NTPYLLNHAL ERLLRGHGHA ASDIIHFTDY 
0141 VVERGSDKHI AYAASKAALD NMTRSFARKL APEVKVNSIA PSLILFNEHD DAEYRQQALN KSLMKTAPGE 
0211 KEVIDLVDYL LTSCFVTGRS FPLDGGRHLR
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             AATGGTGCTG ATTGGCATGC TGTTAATTGC 
-070 CTCAGTTCCG GCGACCTGGA TGCTGGTGGG ATAACGTTCA TCCCATCGTT GGATAGCAAA GGAGATAACG 
0001 atgggtaaaa cccagccctt gccaatatta attactggcg gaggtcgtcg catcggcctc gccctcgcat 
0071 ggcatttcat taatcaaaag caaccggtga ttgtcagcta tcggacacac tatccagcca ttgatggact 
0141 gattaatgca ggtgcgcagt gtattcaggc tgatttttcg accaacgacg gtgtgatggc gtttgccgat 
0211 gaagtactaa aaagcaccca tggtctgcgt gctattttgc ataacgccag tgcgtggatg gcggaaaaac 
0281 cgggtgcgcc actggccgac gtactggctt gcatgatgca gatccacgtt aataccccat acctgctcaa 
0351 ccatgcgctg gaaagattac tgcgtgggca cggacacgcc gccagcgata tcattcactt taccgattat 
0421 gtggtggagc gcggtagcga caaacatatt gcgtatgctg caagcaaagc ggcactggat aatatgaccc 
0491 gctcgtttgc ccgcaagctg gcaccggaag tgaaagtgaa ttctattgcg ccatcgctga tcctgtttaa 
0561 tgaacatgat gatgccgaat atcgacaaca ggcgctgaat aaatcactga tgaaaaccgc gcctggcgag 
0631 aaagaagtga tcgacctggt cgattactta cttaccagtt gctttgtcac cggacgcagt ttcccacttg 
0701 atggcggtcg tcatctgcgt taaTGCAGCT TTATCCAGCA TATAATCAAC ACCCATGCGC TTATCCCCCA 
0771 ACACGCAACA GAACCAACAA AAGCGGCGGG CAAGCGCATC ATTCCGGTGA AAT