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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Mol Gen Genet. 1998;258(1-2):156-65.
Transport activity of FhuA, FhuC, FhuD, and FhuB derivatives in a system free of polar effects, and stoichiometry of components involved in ferrichrome uptake.
Mademidis A, Koster W.
(
9613584
)
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Deletion
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OCR33-15
(D)
,
OCR33-3
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
fhuB
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Related strains
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Strains Search
|
Search strains by gene name:
fhuB
Search strains by all related name:
fhuB b0153 ECK0152 JW0149
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General information (Go to Linear View: )
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Gene Name
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fhuB
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Alternative name
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b0153,ECK0152,JW0149
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Location, Length
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171,462 - 173,444
(
+
)
;
3.70
min
;
1983
(bp) ,
660
(aa)
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Product
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fused iron-hydroxamate transporter subunits of ABC superfamily: membrane components
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Operon Name
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fhuACDB
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Note
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GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
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Function
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transport; Transport of small molecules: Cations
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Gene Ontology
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GO:0005215
;
transporter activity ( fhuB )
GO:0005506
;
iron ion binding ( fhuB )
GO:0005886
;
plasma membrane ( fhuB )
GO:0006810
;
transport ( fhuB )
GO:0006811
;
ion transport ( fhuB )
GO:0006826
;
iron ion transport ( fhuB )
GO:0006835
;
dicarboxylic acid transport ( fhuB )
GO:0016020
;
membrane ( fhuB )
GO:0016021
;
integral to membrane ( fhuB )
GO:0017153
;
sodium:dicarboxylate symporter activity ( fhuB )
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PID
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1786347
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EC number
(KEGG Pathway)
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|
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
FHUB_ECOLI
(
P06972
;
P77372
)
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- Protein name
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Ferrichrome transport system permease protein fhuB
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- Synonyms
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Ferrichrome uptake protein fhuB
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- Gene name
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Name=fhuB; OrderedLocusNames=b0153;
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MMBR References
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J Bacteriol. 1983;156(3):1301-14.
Cloning and expression of the fhu genes involved in iron(III)-hydroxamate uptake by Escherichia coli.
Fecker L, Braun V.
(
6315685
)
|
J Bacteriol. 1980;143(1):256-64.
Genetic control of hydroxamate-mediated iron uptake in Escherichia coli.
Kadner RJ, Heller K, Coulton JW, Braun V.
(
6249788
)
|
Mol Gen Genet. 1986;204(3):435-42.
Iron hydroxamate transport of Escherichia coli: nucleotide sequence of the fhuB gene and identification of the protein.
Koster W, Braun V.
(
3020380
)
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J Bacteriol. 1984;157(3):874-80.
Genetic and biochemical characterization of the Escherichia coli K-12 fhuB mutation.
Prody CA, Neilands JB.
(
6321441
)
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Mol Gen Genet. 1983;192(1-2):131-9.
Plasmid and chromosomal mutants in the iron(III)-aerobactin transport system of Escherichia coli. Use of streptonigrin for selection.
Braun V, Gross R, Koster W, Zimmermann L.
(
6316109
)
|
| Sequences |
Amino acid
FASTA format
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0001 MSKRIALFPA LLLALLVIVA TALTWMNFSQ ALPRSQWAQA AWSPDIDVIE QMIFHYSLLP RLAISLLVGA
0071 GLGLVGVLFQ QVLRNPLAEP TTLGVATGAQ LGITVTTLWA IPGAMASQFA AQAGACVVGL IVFGVAWGKR
0141 LSPVTLILAG LVVSLYCGAI NQLLVIFHHD QLQSMFLWST GTLTQTDWGG VERLWPQLLG GVMLTLLLLR
0211 PLTLMGLDDG VARNLGLALS LARLAALSLA IVISALLVNA VGIIGFIGLF APLLAKMLGA RRLLPRLMLA
0281 SLIGALILWL SDQIILWLTR VWMEVSTGSV TALIGAPLLL WLLPRLRSIS APDMKVNDRV AAERQHVLAF
0351 ALAGGVLLLM AVVVALSFGR DAHGWTWASG ALLEDLMPWR WPRIMAALFA GVMLAVAGCI IQRLTGNPMA
0421 SPEVLGISSG AAFGVVLMLF LVPGNAFGWL LPAGSLGAAV TLLIIMIAAG RGGFSPHRML LAGMALSTAF
0491 TMLLMMLQAS GDPRMAQVLT WISGSTYNAT DAQVWRTGIV MVILLAITPL CRRWLTILPL GGDTARAVGM
0561 ALTPTRIALL LLAACLTATA TMTIGPLSFV GLMAPHIARM MGFRRTMPHI VISALVGGLL LVFADWCGRM
0631 VLFPFQIPAG LLSTFIGAPY FIYLLRKQSR
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CCGGACGCTT TCAGCGCGTA CCTGCAGTCT
-070 GGTTTTATGG TGCGACGCTC TCGGCAATGC ACTTTGTGCG CGTTCTGGAT AACGCCATCG GAGGTAAAGC
0001 gtgagtaaac gaattgcgct tttcccggcg ttattgctgg cgctgttagt gattgtcgct acggcgctca
0071 cctggatgaa cttctcgcag gcgctgccgc gtagccagtg ggcgcaggct gcctggtcgc cggatattga
0141 cgtcatcgag cagatgattt ttcactacag cttgttgccg cgtctggcga tttcgctgct ggtgggcgcg
0211 ggtctggggc tggtgggcgt gctgtttcag caagtgctgc gtaacccgct ggcggagccg acgacgcttg
0281 gcgttgctac aggcgcgcaa ctggggatta ccgtcactac gctctgggcg atccctggtg cgatggcgag
0351 ccagtttgct gcgcaggcag gggcttgtgt tgttggctta attgtctttg gcgtcgcgtg ggggaaacgg
0421 ctgtcgccgg taacgctgat tctcgcgggg ttggtagtga gcctttattg cggcgcaatc aatcagttac
0491 tggttatctt ccatcatgac caactgcaaa gcatgtttct gtggagcact ggaacgctga cgcaaaccga
0561 ctggggcggc gttgagcgtt tatggccgca gctgctgggc ggtgtgatgc tgacgttgct gctacttcgt
0631 ccgttaaccc tgatggggct tgatgatggc gtggcgcgca atctcgggct ggccttgtcg cttgcgcgtc
0701 tggcagcgct gtcgctggcg attgtcatca gtgcgctgct ggtgaacgct gtggggatta tcggctttat
0771 cgggttgttc gcgccgctgc tggcaaaaat gctgggggcg cggcgtctgc tgccacgact gatgctggcg
0841 tcgttgattg gtgcgctgat cctctggctt tccgatcaaa tcatcctctg gctgactcgc gtgtggatgg
0911 aagtgtccac cggttcggtc actgcgttga tcggtgcgcc gctgctactg tggctgttgc cgcgtttacg
0981 cagcattagc gcgccggata tgaaggtcaa cgatcgtgtc gcggctgaac gccaacatgt gctggcgttt
1051 gccctcgcgg gcggcgtgct gctgttgatg gctgtggtgg tggcgctgtc gtttggtcgt gatgcgcacg
1121 gctggacgtg ggcgagcggg gcgttgctcg aggatttaat gccctggcgc tggccgcgaa ttatggcggc
1191 gctgtttgcg ggcgtcatgc tggcggtggc gggctgtatt attcagcgac tgaccggaaa cccgatggca
1261 agcccggaag tgctggggat tagctccggc gcggcgtttg gcgtggtgtt gatgctgttt ctggtgccgg
1331 gtaatgcctt tggctggctg ttacctgcag gcagtctcgg cgcggcggtg acgctgttga tcattatgat
1401 cgccgccggc cgcggtggat tttccccaca ccgtatgtta ctggcgggga tggcgttaag caccgcgttc
1471 accatgcttt tgatgatgtt gcaggcaagt ggtgacccgc gaatggcgca agtgctgacc tggatttccg
1541 gttcgaccta caacgcgacc gatgcgcagg tctggcgcac cggaattgtg atggtgattt tgctggcgat
1611 taccccgctg tgccgccgct ggctgaccat tttaccgctg ggtggtgata ccgcccgagc cgtaggaatg
1681 gcgctgacgc cgacgcgaat tgcgctgctg ctgttagcgg cttgcctgac ggcgaccgcg acgatgacta
1751 ttggaccgtt gagttttgtt ggtttaatgg caccgcatat tgcgcggatg atgggctttc gacggacgat
1821 gccacacatc gtaatttcgg cgctggtggg tggtttactg ctggtgttcg ctgactggtg tgggcggatg
1891 gtgctgtttc cattccagat cccggcgggg ctgctgtcaa cctttatcgg cgcgccatat tttatctatt
1961 tgttgagaaa gcagagccgt taaTTTTTCC ATATAACGGC CCTGTACGCC TGGACGGATA AAGCGTTTAC
2031 GCGACAACGG ATGCCCGATG CGACGCTGGC GCGTCTTATC GGGCCTACAA ACG
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